Contacting Members

Aaron Lim

Aaron Lim

Aaron Lim

MSc Applied Mathematics (U of A), BSc Mathematics (Honours) (U of A)

  • DPhil Student in the Centre for Mathematical Biology

eMail: Aaron [dot] Lim [-at-] maths [dot] ox [dot] ac [dot] uk
Contact Form

Phone Number(s):

Reception/Secretary: +44 1865 273525
Direct: +44 1865 283878

Office: DH56

Preferred Address:

Wolfson College,
Linton Road
Oxford OX2 6UD
England

Departmental Address:

Mathematical Institute
24-29 St Giles'
Oxford
OX1 3LB
England

Research Interests: 

I am interested in mathematical modelling of the within-host dynamics of virus infection, specifically that of the human T-cell lymphotropic virus type 1 (HTLV-I).

My research focus is on the unresolved issues of viral persistence and pathogenesis:  How is the virus able to persist and avoid viral clearance despite the presence of vigorous positive selection by host immunity? What are the key factors that determine HTLV-I-associated disease progression?

Formulating and analysing mathematical models could help offer insights into the complex mechanisms underlying HTLV-I infection and persistence. A deeper understanding of these issues is a crucial step to developing effective ways to disrupt the virus life-cycle and may help identify promising new treatment strategies to reduce the severity of HTLV-I infection and associated disease.

Keywords: HTLV-I, mathematical modelling in immunology, differential equations and dynamical systems.

Prizes, Awards and Scholarships: 
  • 2012 - 2013 TMX Montreal Exchange CCSF Scholarship, Canadian Centennial Scholarship Fund UK
  • 2011 - 2012 Sir James Lougheed Award of Distinction, Alberta Scholarships Program
  • 2011 & 2012 Conference Travel Grant, Wolfson College
  • 2010 - 2012 NSERC Postgraduate Scholarship - Doctoral, Natural Sciences and Engineering Research Council of Canada
Major/Recent Publications: 

M. Y. Li and A. G. Lim (2011) Modelling the Role of Tax Expression in HTLV-I Persistence in vivo. Bull. Math. Biol., 73(12):3008-29.

Teaching: 

OXFORD UNIVERSITY

  • Oct 2010 - Present: Teaching Assistant

Duties: Marking problem sheets, demonstrating problems to students

Classes: Mathematical Ecology and Biology, Applied Partial Differential Equations

Further Details: 

SELECTED PRESENTATIONS

  • May 2013 'Unravelling the host-virus interaction in HTLV-I infection'

Contributed Talk (20 minutes), Modelling Biological Evolution 2013 Conference, University of Leicester, Leicester, UK

  • Apr 2013 'A multi-locus approach to modelling HTLV-I infection'

Invited Research Talk (30 minutes), IRL, University of Alberta, Edmonton, Canada

  • Jul 2012 'HTLV-I infection: A dynamic struggle between viral persistence and host immunity'

Contributed Talk (20 minutes), 2012 Annual Meeting and Conference of the Society for Mathematical Biology, Knoxville, Tennessee, USA.

  • Jun 2012 'Modelling anti-viral host immunity in persistent HTLV-I infection'

Contributed Talk (20 minutes), 2012 Graduate Systems Biology Conference, Oxford University, Oxford, UK.

  • Jul 2011 'Modelling viral persistence in the presence of host immunity in chronic HTLV-I infection'

Contributed Talk (30 minutes), 5th G. J. Butler Memorial Conference on Differential Equations and Population Biology, University of Alberta, Edmonton, Canada.

  • Feb 2011 'Modelling HTLV-I Infection and Persistence'

Poster, 2011 Oxford SIAM Student Chapter Conference, St. Anne's College, Oxford University, Oxford, UK.
Last updated by on Wed, 08/05/2013 - 2:30am.
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