Past Forthcoming Seminars

E.g., 2019-08-18
E.g., 2019-08-18
E.g., 2019-08-18
10 December 2019
17:00
Chris Budd

Further Information: 

Chris Budd is a British mathematician known especially for his contribution to non-linear differential equations and their applications in industry. He is currently Professor of Applied Mathematics at the University of Bath, and Professor of Geometry at Gresham College.

Chris is a passionate populariser of mathematics, reflected in his appointment as Chair of Mathematics of the Royal Institution of Great Britain in 2000. He works on a number of projects with schools and has written a book, "Mathematics Galore", based on his series of popular talks. He was awarded the Order of the British Empire (OBE) in the Queen's Birthday Honours List in 2015 for services to science and maths education.

Please email external-relations@maths.ox.ac.uk to register.

Watch live:

https://www.facebook.com/OxfordMathematics/
https://livestream.com/oxuni/Budd

The Oxford Mathematics Public Lectures are generously supported by XTX Markets.

2 December 2019
17:30
Carlo Rovelli

Further Information: 

Oxford Mathematics Public Lectures- The Roger Penrose Lecture

Carlo Rovelli  - Spin networks: the quantum structure of spacetime from Penrose's intuition to Loop Quantum Gravity

Monday 2 December 2019

In developing the mathematical description of quantum spacetime, Loop Quantum Gravity stumbled upon a curious mathematical structure: graphs labelled by spins. This turned out to be precisely the structure of quantum space suggested by Roger Penrose two decades earlier, just on the basis of his intuition. Today these graphs with spin, called "spin networks" have become a common tool to explore the quantum properties of gravity. In this talk Carlo will tell this beautiful story and illustrate the current role of spin networks in the efforts to understand quantum gravity.

Carlo Rovelli is a Professor in the Centre de Physique Théorique de Luminy of Aix-Marseille Université where he works mainly in the field of quantum gravity and  is a founder of loop quantum gravity theory. His popular-science book 'Seven Brief Lesson on Physics' has been translated into 41 languages and has sold over a million copies worldwide.

5.30pm-6.30pm, Mathematical Institute, Oxford

Please email external-relations@maths.ox.ac.uk to register.

Watch live:
https://facebook.com/OxfordMathematics
https://livestream.com/oxuni/rovelli

The Oxford Mathematics Public Lectures are generously supported by XTX Markets.

29 November 2019
14:00
Abstract

When cells migrate through constricting pores, there is an increase in DNA damage and mutations. Experimental observations show that this breakage is not due to mechanical stress. I present an elastic-fluid model of the cell nucleus, coupled to kinetics of DNA breakage and repair proposing a mechanism by which nuclear deformation can lead to DNA damage. I show that segregation of soluble repair factors from the chromatin during migration leads to a decrease in the repair rate and an accumulation of damage that is sufficient to account for the extent of DNA damage observed experimentally.

In the second part I will talk about how some types of cancer cells grow uncontrollably. Telomeres are DNA caps on the end of chromosomes and are shortened during each cell division. Tumour cells elongate their telomeres so that unlike healthy cells they do not undergo programmed death. I will show how some types of cancer cells can control microphase separation to form micelle-like structures with telomeres in the cores. This clustering of telomeres is a crucial step in the elongation process and understanding the physics involved can help us understand how this process could be disrupted.

  • Mathematical Biology and Ecology Seminar

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