Cell polarity in the rod-shaped bacterium Myxococcus xanthus is crucial for the direction of movement of individual cells. Polarity is governed by a regulatory system characterized by a dynamic spatiotemporal oscillation of proteins between the opposite cell poles. A mathematical framework for a minimal macroscopic model is presented which produces self-sustained regular oscillations of the protein concentrations. The mathematical model is based on a reaction-diffusion PDE system and is independent of external triggers. Necessary conditions on the reaction terms leading to oscillating solutions are derived theoretically. Possible scenarios for protein interaction are numerically tested for robustness against parameter variation. Finally, possible extensions of the model will be addressed.
