Author
Prescott, T
Papachristodoulou, A
IEEE
Journal title
2016 EUROPEAN CONTROL CONFERENCE (ECC)
DOI
10.1109/ECC.2016.7810558
Last updated
2020-07-15T08:47:59.823+01:00
Page
1838-1843
Abstract
© 2016 EUCA. Synthetic biologists rely on mathematical modelling to predict and tune the behaviour of experimentally implementable biomolecular systems. In addition to electronic engineering and control/system theoretic ideas, other characteristic properties of biological systems can be used to achieve complex behaviours. This paper considers the use of timescale separation and layered architectures in synthetic biomolecular systems. We discuss how, by constructing a biomolecular reaction network on two timescales, we are able (a) to implement nonlinear, tunable constraints on a network's state independently of its slow-scale dynamics, and (b) to control the slow dynamics of a network's state in a constrained state space.
Symplectic ID
686641
Download URL
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000392695300305&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=4fd6f7d59a501f9b8bac2be37914c43e
Publication type
Conference Paper
ISBN-13
9781509025916
Publication date
2016
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