+44 1865 273935
University of Oxford
Andrew Wiles Building
Radcliffe Observatory Quarter
Generally, I am interested in the ways mathematical instabilities can serve as analogues for the development of disease in biological systems. My DPhil primarily focusses on using mathematical and computational models to elucidate different mechanisms that are known to play a role in gut tissue formation. The nature of my current projects range from the biochemical to the biomechanical, and require the use of tools on both the individual-based and continuum level.
Current projets include:
- The effect of mechanical heterogeneity in gut tissue formation, with applications to colorectal cancer and inflammatory bowel disease.
- The role of the circadian clock gating of cell cycles in the intestinal stem cell niche.
2016 - 2017:
- B5.1 Stochastic Modelling of Biological Processes
- B5.5 Further Mathematical Biology
Prizes, Awards, and Scholarships:
- CRUK Oxford Centre DPhil Prize Studentship
- Mathematical Institute Studentship
Major / Recent Publications:
- A.J. Langlands, A.A. Almet, P.L. Appleton, I.P. Newton, J.M. Osborne, I.S. Näthke, Paneth cell-rich regions separated by a cluster of Lgr5+ cells initiate crypt fission in the intestinal stem cell niche, PLoS Biology, 14 (6): e1002491 (2016), 31 pp.
- A.A. Almet, M. Pan, B.D. Hughes, K.A. Landman, When push comes to shove: Exclusion processes with nonlocal consequences, Physica A 437 (2015) pp. 119—129