+44 1865 273935
University of Oxford
Andrew Wiles Building
Radcliffe Observatory Quarter
I am interested in the mechanics of tissue morphogenesis and how biological tissues integrate mechanical cues with subcellular biochemical information. To date, my work has been applied to the intestinal epithelium, the fastest self-renewing organ in the body and where colorectal cancer initiates. I combine individual-based and continuum-level models of gut tissue to investigate the influence of different biomechanical factors that are suspected to play a role in both health and disease.
2018 - 2019:
M5 Fourier Series and PDEs
2017 - 2018:
- M5 Fourier Series and PDEs
2016 - 2017:
- B5.1 Stochastic Modelling of Biological Processes
- B5.5 Further Mathematical Biology
Prizes, awards, and scholarships:
- Merton College Postgraduate Research Prize Scholarship 2018-19
- CRUK Oxford Centre DPhil Prize Studentship
- Mathematical Institute Studentship
Major / recent publications:
- A.A. Almet, H.M. Byrne, P.K. Maini, D.E. Moulton, Post-buckling behaviour of a growing elastic rod, Journal of Mathematical Biology 77 (4) (2018) pp. 1—38.
- D. Muraro, A. Parker, L. Vaux, S. Filippi, A.A. Almet, A.G. Fletcher, A.J.M. Watson, C. Pin, P.K. Maini, H.M. Byrne, Chronic TNFalpha-driven injury delays cell migration to villi in the intestinal epithelium, Journal of the Royal Society Interface 15 (145) (2018), p.20180037.
- A.A. Almet, B.D. Hughes. K.A. Landman, I.S. Näthke, J.M. Osborne, A multicellular model of intestinal crypt fission and buckling, Bulletin of Mathematical Biology 80 (2) (2018), pp. 335—359.
- A.J. Langlands, A.A. Almet, P.L. Appleton, I.P. Newton, J.M. Osborne, I.S. Näthke, Paneth cell-rich regions separated by a cluster of Lgr5+ cells initiate crypt fission in the intestinal stem cell niche, PLoS Biology, 14 (6): e1002491 (2016), 31 pp.
- A.A. Almet, M. Pan, B.D. Hughes, K.A. Landman, When push comes to shove: Exclusion processes with nonlocal consequences, Physica A 437 (2015) pp. 119—129.