+44 1865 273935
University of Oxford
Andrew Wiles Building
Radcliffe Observatory Quarter
I am interested in the ways mathematical instabilities can serve as analogues for the development of disease in biological systems. More specifically, my work has been applied to the intestinal epithelium, the fastest self-renewing organ in the body and the source of colorectal cancer and inflammatory bowel disease. My DPhil primarily focusses on using both individual-based and continuum-level models to determine the influence of different biomechanical factors that are suspected to play a role in both healthy and diseased gut tissue formation.
2017 - 2018:
- M5 Fourier Series and PDEs
2016 - 2017:
- B5.1 Stochastic Modelling of Biological Processes
- B5.5 Further Mathematical Biology
Prizes, Awards, and Scholarships:
- Merton College Postgraduate Research Prize Scholarship 2018-19
- CRUK Oxford Centre DPhil Prize Studentship
- Mathematical Institute Studentship
Major / Recent Publications:
- D. Muraro, A. Parker, L. Vaux, S. Filippi, A.A. Almet, A.G. Fletcher, A.J.M. Watson, C. Pin, P.K. Maini, H.M. Byrne, Chronic TNFalpha-driven injury delays cell migration to villi in the intestinal epithelium, Journal of the Royal Society Interface (accepted).
- A.A. Almet, H.M. Byrne, P.K. Maini, D.E. Moulton, Post-buckling behaviour of a growing elastic rod, Journal of Mathematical Biology (accepted).
- A.A. Almet, B.D. Hughes. K.A. Landman, I.S. Näthke, J.M. Osborne, A multicellular model of intestinal crypt fission and buckling, Bulletin of Mathematical Biology (2017), 25pp.
- A.J. Langlands, A.A. Almet, P.L. Appleton, I.P. Newton, J.M. Osborne, I.S. Näthke, Paneth cell-rich regions separated by a cluster of Lgr5+ cells initiate crypt fission in the intestinal stem cell niche, PLoS Biology, 14 (6): e1002491 (2016), 31 pp.
- A.A. Almet, M. Pan, B.D. Hughes, K.A. Landman, When push comes to shove: Exclusion processes with nonlocal consequences, Physica A 437 (2015) pp. 119—129