Jessica McGillen

 Jessica McGillen

Jessica McGillen

BS, MS Computational Biology, Carnegie Mellon University

  • 3rd year DPhil candidate

eMail: Jessica [dot] McGillen [-at-] maths [dot] ox [dot] ac [dot] uk
Contact Form

Phone Number(s):

Reception/Secretary: +44 1865 273525

Office: DH56

Departmental Address:

Mathematical Institute
24-29 St Giles'
Oxford
OX1 3LB
England

Research Interests: 

I am interested in altered energy metabolism in cancer, specifically in aspects of the glycolytic phenotype and related pH regulation. My work is motivated by viewing a tumour as a heterogeneous population evolving within the microenvironment of its host tissue, a framework which attempts to confront the true spatio-temporal complexity of cancer and enables the application of mathematical techniques originally used for studying ecosystems.

Prizes, Awards and Scholarships: 

Invited visitor to the Institute for Systems Theory and Automatic Control, University of Stuttgart, Germany to give a talk on modelling aspects of metabolism in avascular tumours (upcoming in June 2013).

Invited speaker in a cancer minisymposium at the Modelling Biological Evolution 2013 Conference, Leicester, UK (May 2013).

Overseas Graduate Scholarship from St. Catherine's College for academic achievement, Oxford University (October 2011-present).

Prize for best presentation at the Doctoral Training Centre 4th Year Conference, Oxford University (February 2013).

Invited visitor to the Universidad de Castilla-La Mancha in Ciudad Real, Spain for a month of collaborative work with the group of Prof. Victor M. Pérez García (September 2012).

Landahl Travel Grant to give a talk at the Society for Mathematical Biology Annual Conference, Knoxville, TN, USA (July 2012).

Invited speaker at the inaugural meeting of the St. Catherine's College Biomedical Society, Oxford University (November 2011).

ESMTB travel grant to present a poster at the 8th European Conference on Mathematical and Theoretical Biology, Krakow, Poland (June 2011).

Certificate of Merit for Outstanding Undergraduate Research in Biological Sciences, Carnegie Mellon University, PA, USA (May 2006).

Major/Recent Publications: 

McGillen JB, Gaffney EA, Martin NK, Maini PK. A general reaction-diffusion model of acidity in cancer invasion. Journal of Mathematical Biology. In press; published online 23 March 2013 (http://link.springer.com/article/10.1007/s00285-013-0665-7#page-1).

McGillen JB, Martin NK, Robey IF, Gaffney EA, Maini PK. Applications of mathematical analysis to tumour acidity modelling. Far-From-Equilibrium Dynamics, Proceedings of the Kyoto University Research Institute for Mathematical Sciences, B31: 31-59, 2012.

Teaching: 

Teaching Assistant for C6.3a Perturbation Methods, C8.1b Mathematical Physiology, and B8a Mathematical Ecology and Biology (2010-2012).

Further Details: 

Selected presentations

Talks:

'Acidity in the tumour-host microenvironment', Modelling Biological Evolution 2013 Conference, Leicester, UK (May 2013).

'The role of acidity in cancer', Doctoral Training Centre 4th Year Conference, Oxford University (February 2013).

'A generalised model of tumour acidity and invasion',

  • Society for Mathematical Biology Annual Conference, Knoxville, Tennessee, USA (July 2012)
  • Mathways Into Cancer Conference, Almagro, Spain (June 2012)
  • Systems Biology Student Conference, Oxford University (June 2012)

'Mathematical modelling of tumour acidity and invasion', inaugural meeting of the St. Catherine's College Biomedical Society, Oxford University (November 2011).

Poster:

'Mathematical modelling of cancer ecology', 8th European Conference on Mathematical and Theoretical Biology, Krakow, Poland (June 2011).