New faecal calprotectin cut-off points for remission and active disease defined by UCEIS and Nancy indices in ulcerative colitis (UC)

Disease activity assessment is an essential part of clinical management in UC, most accurately evaluated by endoscopy and biopsy, since patient symptoms may not reliably reflect activity. Published cut-offs for faecal calprotectin (FCal) in UC are largely based on prediction of relapse, rather than prediction of endoscopic or histopathologic activity.