​Current research:

As part of my DPhil project, I am working in collaboration with AstraZeneca on mathematical modelling of immunotherapy treatments. Immunotherapies are new promising tools, which aim to stimulate the body's own immune system to attack cancer cells. Despite success of such treatments so far, clinical trials still show a large group of patients, who do not respond to immunotherapeutic drugs. In order to increase response rates, a better understanding of the complex interactions between tumour and immune cells is needed. We are looking at bifurcating/bistable ordinary differential equations models of tumour-immune interactions, and feasibilty of integration of such models with data from preclinical trials. This can shed more light into the mechanisms leading to no response to treatment.

Other areas of interest:

• Mathematical modelling in biology and medicine
• Parameter identifiability
• Data assimilation
• Stochastic processes
• Scientific computing
• Machine learning