The observations of the first traces of cosmic structure in the
Cosmic Microwave Background are in excellent agreement with the
predictions of Inflation. However as we shall see, that account
is not fully satisfactory, as it does not address the transition
from an homogeneous and isotropic early stage to a latter one
lacking those symmetries. We will argue that new physics along the
lines of the dynamical quantum state reduction theories is needed
to account for such transition and, motivated by Penrose's ideas
suggest that quantum gravity might be the place from where
this new physics emerges. Moreover we will show that observations
can be used to constrain the various phenomenological proposals
made in this regard.