The use of hybrid cellular automaton models for improving cancer therapy

The Hybrid Cellular Automata (HCA) modelling framework can be an efficient approach to a number of biological problems, particularly those which involve the integration of multiple spatial and temporal scales. As such, HCA may become a key modelling tool in the development of the so-called integrative biology. In this paper, we first discuss HCA on a general level and then present results obtained when this approach was implemented in cancer research.