We describe a network model for the progression of Alzheimer's disease based on the underlying relationship to toxic proteins. From human patient data we construct a network of a typical brain, and simulate the concentration and build-up of toxic proteins, as well as the clearance, using reaction--diffusion equations. Our results suggest clearance plays an important role in delaying the onset of Alzheimer's disease, and provide a theoretical framework for the growing body of clinical results.

Holography, which reveals a specific correspondence between gravitational and quantum theories, is an ongoing area of research that has known a lot of interest these past decades. The duality of holography has many applications: it provides an interpretation for black hole entropy in terms of microstates, it helps our understanding of solid state properties such as superconductivity and strongly coupled quantum systems, and it even offers insight into the mysterious realm of quantum gravity. 

In this talk, I will first introduce the concept of holography and some of its applications. I will then discuss some notions of string theory and geometry that are commonly used in holography. Finally, if time permits, I will present some of our latest results, where we match the energy of membranes in supergravity to properties of the dual quantum models.

The resolvents of finite volume restricted Hamiltonians, G^(⍵), have long been used to describe the localization of quantum systems. More recently, projected Green's functions (pGfs) -- finite volume restrictions of the resolvent -- have been applied to translation invariant free fermion systems, and the pGf zero eigenvalues have been shown to determine topological edge modes in free-fermion systems with bulk-edge correspondence. In this talk, I will connect the pGfs to the G^(⍵) appearing in the transfer matrices of quasi-periodic systems and discuss what pGF zeros can tell us about the solutions to transfer matrix equations. Using these methods, we re-examine the critical almost-Matthieu operator and notice new guarantees on analytic regions of its resolvent for Liouville irrationals.