Provisional (A mathematical theory for aneurysm initiation)

When a rubber membrane tube is inflated, a localized bulge will initiate when the internal pressure reaches a certain value known as the initiation pressure. As inflation continues, the bulge will grow in diameter until it reaches a maximum size, after which the bulge will spread in both directions. This simple phenomenon has previously been studied both experimentally, numerically, and analytically, but surprisingly it is only recently that the character of the initiation pressure has been fully understood. In this talk, I shall first show how the entire inflation process can be described analytically, and then apply the ideas to the mathematical modelling of aneurysm initiation in human arteries.