Date
Thu, 20 Feb 2014
Time
16:00 - 17:00
Location
L3
Speaker
Rafal Bogacz
Organisation
University of Oxford (Neuroscience)

In Parkinson’s disease, increased power of oscillations in firing rate has been observed throughout the cortico-basal-ganglia circuit. In

particular, the excessive oscillations in the beta range (13-30Hz) have been shown to be associated with difficulty of movement initiation. However, on the basis of experimental data alone it is difficult to determine where these oscillations are generated, due to complex and recurrent structure of the cortico-basal-ganglia-thalamic circuit. This talk will describe a mathematical model of a subset of basal-ganglia that is able to reproduce experimentally observed patterns of activity. The analysis of the model suggests where and under which conditions the beta oscillations are produced.

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