While many cubic fourfolds are known to be rational, it is expected that the very general cubic fourfold is irrational (although none have been
proven to be so). There is a conjecture for precisely which cubics are rational, which can be expressed in Hodge-theoretic terms (by work of Hassett)
or in terms of derived categories (by work of Kuznetsov). The conjecture can be phrased as saying that one can associate a `noncommutative K3 surface' to any cubic fourfold, and the rational ones are precisely those for which this noncommutative K3 is `geometric', i.e., equivalent to an honest K3 surface. It turns out that the noncommutative K3 associated to a cubic fourfold has a conjectural symplectic mirror (due to Batyrev-Borisov). In contrast to the algebraic side of the story, the mirror is always `geometric': i.e., it is always just an honest K3 surface equipped with an appropriate Kähler form. After explaining this background, I will state a theorem: homological mirror symmetry holds in this context (joint work with Ivan Smith).