Tensors in biological data and algebraic statistics

21 February 2020

Tensors are higher dimensional analogues of matrices, used to record data with multiple changing variables. Interpreting tensor data requires finding multi-linear stucture that depends on the application or context. I will describe a tensor-based clustering method for multi-dimensional data. The multi-linear structure is encoded as algebraic constraints in a linear program. I apply the method to a collection of experiments measuring the response of genetically diverse breast cancer cell lines to an array of ligands. In the second part of the talk, I will discuss low-rank decompositions of tensors that arise in statistics, focusing on two graphical models with hidden variables. I describe how the implicit semi-algebraic description of the statistical models can be used to obtain a closed form expression for the maximum likelihood estimate.

  • Mathematical Biology and Ecology Seminar