+44 1865 273522
University of Oxford
Andrew Wiles Building
Radcliffe Observatory Quarter
I work in the Wolfson Centre for Mathematical Biology on the modelling of tumour-immune interactions, specifically focussing on macrophages. Macrophages are a type of immune cell which ordinarily attack invaders like bacteria when you're injured. But in cancer, macrophages are tricked by the tumour into pumping out growth factors which help blood vessels grow and bring oxygen to the tumour rather than attacking it. I aim to use mathematical modelling to understand the mechanisms through which tumours prevent macrophages from attacking them, and to propose circumstances where drugs targeting these mechanisms will be most effective.
A large part of my work involves analysing image data provided by my industrial collaborators at Roche. These are histological images of tumours, but due to the size of the files I use "superpixels" to help reduce the complexity of the data. This basically involves merging nearby pixels into blobs according to their colour while trying to leave the picture looking as close to how it did before as possible. Don't be deceived, the picture of me on this page isn't just a bit blurry - I couldn't resist running it through the superpixellation algorithm which I use! You can find some more examples of superpixels on this really, really high tech web page.