Thu, 26 Oct 2023

12:00 - 13:00
L1

Adjoint-accelerated Bayesian Inference for joint reconstruction and segmentation of Flow-MRI images

Matthew Juniper
(University of Cambridge)
Abstract

We formulate and solve a generalized inverse Navier–Stokes boundary value problem for velocity field reconstruction and simultaneous boundary segmentation of noisy Flow-MRI velocity images. We use a Bayesian framework that combines CFD, Gaussian processes, adjoint methods, and shape optimization in a unified and rigorous manner.
With this framework, we find the velocity field and flow boundaries (i.e. the digital twin) that are most likely to have produced a given noisy image. We also calculate the posterior covariances of the unknown parameters and thereby deduce the uncertainty in the reconstructed flow. First, we verify this method on synthetic noisy images of flows. Then we apply it to experimental phase contrast magnetic resonance (PC-MRI) images of an axisymmetric flow at low and high SNRs. We show that this method successfully reconstructs and segments the low SNR images, producing noiseless velocity fields that match the high SNR images, using 30 times less data.
This framework also provides additional flow information, such as the pressure field and wall shear stress, accurately and with known error bounds. We demonstrate this further on a 3-D in-vitro flow through a 3D-printed aorta and 3-D in-vivo flow through a carotid artery.

Wed, 25 Oct 2023
17:00
Lecture Theatre 1

Does Life know about quantum mechanics? - Jim Al-Khalili

Jim Al-Khalili
(University of Surrey)
Further Information

Oxford Mathematics Roger Penrose Public Lecture

Does Life know about quantum mechanics? Jim Al-Khalili

Physicists and chemists are used to dealing with quantum mechanics, but biologists have thus far got away without having to worry about this strange yet powerful theory of the subatomic world. However, times are changing. There is now solid evidence that enzymes use quantum tunnelling to accelerate chemical reactions, while plants and bacteria use a quantum trick in photosynthesis – sending lumps of sunlight energy in multiple directions at once. It even appears that some animals have the ability to use quantum entanglement – what Einstein called “spooky action at a distance” – as a compass to ‘see’ the earth’s magnetic field. In our research at the University of Surrey we are discovering that life may even have evolved mechanisms to control genetic mutations caused by quantum tunnelling of protons between strands of DNA. Welcome to the exciting new field of quantum biology.

Jim Al-Khalili CBE FRS is an academic, author and broadcaster. He holds a Distinguished Chair in Theoretical Physics at the University of Surrey where he conducts research in quantum physics. He has written fifteen books on popular science, between them translated into over twenty-six languages. He is a regular presenter of TV science documentaries and the long-running BBC Radio 4 programme, The Life Scientific.

Please email @email to register to attend in person.

The lecture will be broadcast on the Oxford Mathematics YouTube Channel on Wednesday 15 November at 5pm and any time after (no need to register for the online version).

The Oxford Mathematics Public Lectures are generously supported by XTX Markets.

Wed, 25 Oct 2023

16:00 - 17:00
L6

Alternating knots and branched double covers

Soheil Azarpendar
(University of Oxford)
Abstract

An old and challenging conjecture proposed by R.H. Fox in 1962 states that the absolute values of the coefficients of the Alexander polynomial of an alternating knot are trapezoidal i.e. strictly increase, possibly plateau, then strictly decrease. We give a survey of the known results and use them to motivate the study of branched double covers. The second part of the talk focuses on the properties of the branched double covers of alternating knots.

Tue, 24 Oct 2023

16:00 - 17:00
L6

Correlations of the Riemann zeta function

Michael Curran
(University of Oxford)
Abstract

Abstract: Shifted moments of the Riemann zeta function, introduced by Chandee, are natural generalizations of the moments of zeta. While the moments of zeta capture large values of zeta, the shifted moments also capture how the values of zeta are correlated along the half line. I will describe recent work giving sharp bounds for shifted moments assuming the Riemann hypothesis, improving previous work of Chandee and Ng, Shen, and Wong. I will also discuss some unconditional results about shifted moments with small exponents.

Tue, 24 Oct 2023
15:00

Measure doubling for small sets in SO(3,R).

Yifan Jing
Abstract

Let $SO(3,R)$ be the $3D$-rotation group equipped with the real-manifold topology and the normalized Haar measure $\mu$. Confirming a conjecture by Breuillard and Green, we show that if $A$ is an open subset of $SO(3,R)$ with sufficiently small measure, then $\mu(A^2) > 3.99 \mu(A)$. This is joint work with Chieu-Minh Tran (NUS) and Ruixiang Zhang (Berkeley). 

Tue, 24 Oct 2023

14:30 - 15:00
VC

Redefining the finite element

India Marsden
(Oxford)
Abstract

The Ciarlet definition of a finite element has been used for many years to describe the requisite parts of a finite element. In that time, finite element theory and implementation have both developed and improved, which has left scope for a redefinition of the concept of a finite element. In this redefinition, we look to encapsulate some of the assumptions that have historically been required to complete Ciarlet’s definition, as well as incorporate more information, in particular relating to the symmetries of finite elements, using concepts from Group Theory. This talk will present the machinery of the proposed new definition, discuss its features and provide some examples of commonly used elements.

Tue, 24 Oct 2023

14:00 - 15:00
L3

Monochromatic products and sums in N and Q

Matt Bowen
(University of Oxford)
Abstract

We show that every 2-coloring of the natural numbers and any finite coloring of the rationals contains monochromatic sets of the form $\{x, y, xy, x+y\}$. We also discuss generalizations and obstructions to extending this result to arbitrary finite coloring of the naturals. This is partially based on joint work with Marcin Sabok.

Tue, 24 Oct 2023

14:00 - 15:00
L5

Existence and rotatability of the two-colored Jones–Wenzl projector

Amit Hazi
(Leeds University)
Abstract

The two-colored Temperley-Lieb algebra is a generalization of the Temperley-Lieb algebra. The analogous two-colored Jones-Wenzl projector plays an important role in the Elias-Williamson construction of the diagrammatic Hecke category. In this talk, I will give conditions for the existence and rotatability of the two-colored Jones-Wenzl projector in terms of the invertibility and vanishing of certain two-colored quantum binomial coefficients. As a consequence, we prove that Abe’s category of Soergel bimodules is equivalent to the diagrammatic Hecke category in complete generality.

 

Tue, 24 Oct 2023

14:00 - 14:30
VC

Analysis and Numerical Approximation of Mean Field Game Partial Differential Inclusions

Yohance Osborne
(UCL)
Abstract

The PDE formulation of Mean Field Games (MFG) is described by nonlinear systems in which a Hamilton—Jacobi—Bellman (HJB) equation and a Kolmogorov—Fokker—Planck (KFP) equation are coupled. The advective term of the KFP equation involves a partial derivative of the Hamiltonian that is often assumed to be continuous. However, in many cases of practical interest, the underlying optimal control problem of the MFG may give rise to bang-bang controls, which typically lead to nondifferentiable Hamiltonians. In this talk we present results on the analysis and numerical approximation of second-order MFG systems for the general case of convex, Lipschitz, but possibly nondifferentiable Hamiltonians.
In particular, we propose a generalization of the MFG system as a Partial Differential Inclusion (PDI) based on interpreting the partial derivative of the Hamiltonian in terms of subdifferentials of convex functions.

We present theorems that guarantee the existence of unique weak solutions to MFG PDIs under a monotonicity condition similar to one that has been considered previously by Lasry & Lions. Moreover, we introduce a monotone finite element discretization of the weak formulation of MFG PDIs and prove the strong convergence of the approximations to the value function in the H1-norm and the strong convergence of the approximations to the density function in Lq-norms. We conclude the talk with some numerical experiments involving non-smooth solutions. 

This is joint work with my supervisor Iain Smears. 

Tue, 24 Oct 2023
13:00
L1

Duality defects, anomalies and RG flows

Christian Copetti
(Oxford)
Abstract

We review the construction of non-invertible duality defects in various dimensions. We explain how they can be preserved along RG flows and how their realization on gapped phases contains their 't Hooft anomalies. We finally give a presentation of the anomalies from the Symmetry TFT. Time permitting I will discuss some possible future applications.

Tue, 24 Oct 2023
11:00
Lecture Room 4, Mathematical Institute

DPhil Presentations

Akshay Hegde, Julius Villar, Csaba Toth
(Mathematical Institute (University of Oxford))
Abstract

As part of the internal seminar schedule for Stochastic Analysis for this coming term, DPhil students have been invited to present on their works to date. Student talks are 20 minutes, which includes question and answer time. 

Students presenting are:

Akshay Hegde, supervisor Dmitry Beylaev

Julius Villar, supervisor Dmitry Beylaev

Csaba Toth, supervisor Harald Oberhauser 

Mon, 23 Oct 2023

16:30 - 17:30
L3

Graph Limit for Interacting Particle Systems on Weighted Random Graphs

Nastassia Pouradier Duteil
(Sorbonne Université)
Abstract

We study the large-population limit of interacting particle systems posed on weighted random graphs. In that aim, we introduce a general framework for the construction of weighted random graphs, generalizing the concept of graphons. We prove that as the number of particles tends to infinity, the finite-dimensional particle system converges in probability to the solution of a deterministic graph-limit equation, in which the graphon prescribing the interaction is given by the first moment of the weighted random graph law. We also study interacting particle systems posed on switching weighted random graphs, which are obtained by resetting the weighted random graph at regular time intervals. We show that these systems converge to the same graph-limit equation, in which the interaction is prescribed by a constant-in-time graphon.

Mon, 23 Oct 2023
15:30
Lecture Theatre 3, Mathematical Institute, Radcliffe Observatory Quarter, Woodstock Road, OX2 6G

PCF-GAN: generating sequential data via the characteristic function of measures on the path space

Prof Hao Ni
(Dept of Mathematics UCL)
Further Information

Please join us from 1500-1530 for tea and coffee outside the lecture theatre before the talk.

Abstract

Generating high-fidelity time series data using generative adversarial networks (GANs) remains a challenging task, as it is difficult to capture the temporal dependence of joint probability distributions induced by time-series data. To this end, a key step is the development of an effective discriminator to distinguish between time series distributions. In this talk, I will introduce the so-called PCF-GAN, a novel GAN that incorporates the path characteristic function (PCF) as the principled representation of time series distribution into the discriminator to enhance its generative performance.  On the one hand, we establish theoretical foundations of the PCF distance by proving its characteristicity, boundedness, differentiability with respect to generator parameters, and weak continuity, which ensure the stability and feasibility of training the PCF-GAN. On the other hand, we design efficient initialisation and optimisation schemes for PCFs to strengthen the discriminative power and accelerate training efficiency. To further boost the capabilities of complex time series generation, we integrate the auto-encoder structure via sequential embedding into the PCF-GAN, which provides additional reconstruction functionality. Extensive numerical experiments on various datasets demonstrate the consistently superior performance of PCF-GAN over state-of-the-art baselines, in both generation and reconstruction quality. Joint work with Dr. Siran Li (Shanghai Jiao Tong Uni) and Hang Lou (UCL). Paper: [https://arxiv.org/pdf/2305.12511.pdf].

Mon, 23 Oct 2023
15:30
L4

Khovanov homology and the Fukaya category of the three-punctured sphere

Claudius Zibrowius
(Durham University)
Abstract

About 20 years ago, Dror Bar-Natan described an elegant generalisation
of Khovanov homology to tangles with any number of endpoints, by
considering certain quotients of two-dimensional relative cobordism
categories.  I claim that these categories are in general not
well-understood (not by me in any case).  However, if we restrict to
tangles with four endpoints, things simplify and Bar-Natan's category
turns out to be closely related to the wrapped Fukaya category of the
four-punctured sphere.  This relationship gives rise to a symplectic
interpretation of Khovanov homology that is useful both for doing
calculations and for proving theorems.  I will discuss joint work in
progress with Artem Kotelskiy and Liam Watson where we investigate what
happens when we fill in one of the punctures.
 

Mon, 23 Oct 2023
14:15
L4

Einstein metrics on the Ten-Sphere

Matthias Wink
(Münster)
Abstract

In this talk we give an introduction to the topic of Einstein metrics on spheres. In particular, we prove the existence of three non-round Einstein metrics with positive scalar curvature on $S^{10}.$ Previously, the only even-dimensional spheres known to admit non-round Einstein metrics were $S^6$ and $S^8.$ This talk is based on joint work with Jan Nienhaus.

Mon, 23 Oct 2023

14:00 - 15:00
Lecture Room 6

Tractable Riemannian Optimization via Randomized Preconditioning and Manifold Learning

Boris Shustin
(Mathematical Institute University of Oxford)
Abstract

Optimization problems constrained on manifolds are prevalent across science and engineering. For example, they arise in (generalized) eigenvalue problems, principal component analysis, and low-rank matrix completion, to name a few problems. Riemannian optimization is a principled framework for solving optimization problems where the desired optimum is constrained to a (Riemannian) manifold.  Algorithms designed in this framework usually require some geometrical description of the manifold, i.e., tangent spaces, retractions, Riemannian gradients, and Riemannian Hessians of the cost function. However, in some cases, some of the aforementioned geometric components cannot be accessed due to intractability or lack of information.


 

In this talk, we present methods that allow for overcoming cases of intractability and lack of information. We demonstrate the case of intractability on canonical correlation analysis (CCA) and on Fisher linear discriminant analysis (FDA). Using Riemannian optimization to solve CCA or FDA with the standard geometric components is as expensive as solving them via a direct solver. We address this shortcoming using a technique called Riemannian preconditioning, which amounts to changing the Riemannian metric on the constraining manifold. We use randomized numerical linear algebra to form efficient preconditioners that balance the computational costs of the geometric components and the asymptotic convergence of the iterative methods. If time permits, we also show the case of lack of information, e.g., the constraining manifold can be accessed only via samples of it. We propose a novel approach that allows approximate Riemannian optimization using a manifold learning technique.

 

Mon, 23 Oct 2023

13:00 - 14:00
N3.12

Mathematrix: Careers Panel

Abstract

We will have a Q&A with a panel of academics and industry experts on applying to jobs both in and out of academia.

Fri, 20 Oct 2023

16:00 - 17:00
L1

Generalized Tensor Decomposition: Utility for Data Analysis and Mathematical Challenges

Tamara Kolda
( MathSci.ai)
Further Information

Tamara Kolda is an independent mathematical consultant under the auspices of her company MathSci.ai based in California. From 1999-2021, she was a researcher at Sandia National Laboratories in Livermore, California. She specializes in mathematical algorithms and computation methods for tensor decompositions, tensor eigenvalues, graph algorithms, randomized algorithms, machine learning, network science, numerical optimization, and distributed and parallel computing.

From the website: https://www.mathsci.ai/

Abstract

Tensor decomposition is an unsupervised learning methodology that has applications in a wide variety of domains, including chemometrics, criminology, and neuroscience. We focus on low-rank tensor decomposition using  canonical polyadic or CANDECOMP/PARAFAC format. A low-rank tensor decomposition is the minimizer according to some nonlinear program. The usual objective function is the sum of squares error (SSE) comparing the data tensor and the low-rank model tensor. This leads to a nicely-structured problem with subproblems that are linear least squares problems which can be solved efficiently in closed form. However, the SSE metric is not always ideal. Thus, we consider using other objective functions. For instance, KL divergence is an alternative metric is useful for count data and results in a nonnegative factorization. In the context of nonnegative matrix factorization, for instance, KL divergence was popularized by Lee and Seung (1999). We can also consider various objectives such as logistic odds for binary data, beta-divergence for nonnegative data, and so on. We show the benefits of alternative objective functions on real-world data sets. We consider the computational of generalized tensor decomposition based on other objective functions, summarize the work that has been done thus far, and illuminate open problems and challenges. This talk includes joint work with David Hong and Jed Duersch.

Fri, 20 Oct 2023
16:00
L1

Departmental Colloquium (Tamara Kolda) - Generalized Tensor Decomposition: Utility for Data Analysis and Mathematical Challenges

Tamara Kolda
Further Information
Tamara Kolda is an independent mathematical consultant under the auspices of her company MathSci.ai based in California. From 1999-2021, she was a researcher at Sandia National Laboratories in Livermore, California. She specializes in mathematical algorithms and computation methods for tensor decompositions, tensor eigenvalues, graph algorithms, randomized algorithms, machine learning, network science, numerical optimization, and distributed and parallel computing.
Abstract
Tensor decomposition is an unsupervised learning methodology that has applications in a wide variety of domains, including chemometrics, criminology, and neuroscience. We focus on low-rank tensor decomposition using canonical polyadic or CANDECOMP/PARAFAC format. A low-rank tensor decomposition is the minimizer according to some nonlinear program. The usual objective function is the sum of squares error (SSE) comparing the data tensor and the low-rank model tensor. This leads to a nicely-structured problem with subproblems that are linear least squares problems which can be solved efficiently in closed form. However, the SSE metric is not always ideal. Thus, we consider using other objective functions. For instance, KL divergence is an alternative metric is useful for count data and results in a nonnegative factorization. In the context of nonnegative matrix factorization, for instance, KL divergence was popularized by Lee and Seung (1999). We can also consider various objectives such as logistic odds for binary data, beta-divergence for nonnegative data, and so on. We show the benefits of alternative objective functions on real-world data sets. We consider the computational of generalized tensor decomposition based on other objective functions, summarize the work that has been done thus far, and illuminate open problems and challenges. This talk includes joint work with David Hong and Jed Duersch.
Fri, 20 Oct 2023

15:00 - 16:00
L5

Euler characteristic in topological persistence

Vadim Lebovici
(Mathematical Institute, University of Oxford)
Further Information

Vadim Lebovici is a post-doc in the Centre for Topological Data Anslysis. His research interests include: 

  • Multi-parameter persistent homology
  • Constructible functions and Euler calculus
  • Sheaf theory
  • Persistent magnitude
Abstract

In topological data analysis, persistence barcodes record the
persistence of homological generators in a one-parameter filtration
built on the data at hand. In contrast, computing the pointwise Euler
characteristic (EC) of the filtration merely records the alternating sum
of the dimensions of each homology vector space.

In this talk, we will show that despite losing the classical
"signal/noise" dichotomy, EC tools are powerful descriptors, especially
when combined with new integral transforms mixing EC techniques with
Lebesgue integration. Our motivation is fourfold: their applicability to
multi-parameter filtrations and time-varying data, their remarkable
performance in supervised and unsupervised tasks at a low computational
cost, their satisfactory properties as integral transforms (e.g.,
regularity and invertibility properties) and the expectation results on
the EC in random settings. Along the way, we will give an insight into
the information these descriptors record.

This talk is based on the work [https://arxiv.org/abs/2111.07829] and
the joint work with Olympio Hacquard [https://arxiv.org/abs/2303.14040].

 

 

Fri, 20 Oct 2023

15:00 - 16:00
Virtual

Machine learning for identifying translatable biomarkers and targets

Professor Daphne Koller
(Department of Computer Science Stanford University)
Abstract

Modern medicine has given us effective tools to treat some of the most significant and burdensome diseases. At the same time, it is becoming consistently more challenging and more expensive to develop new therapeutics. A key factor in this trend is that we simply don't understand the underlying biology of disease, and which interventions might meaningfully modulate clinical outcomes and in which patients. To achieve this goal, we are bringing together large amounts of high content data, taken both from humans and from human-derived cellular systems generated in our own lab. Those are then used to learn a meaningful representation of biological states via cutting edge machine learning methods, which enable us to make predictions about novel targets, coherent patient segments, and the clinical effect of molecules. Our ultimate goal is to develop a new approach to drug development that uses high-quality data and ML models to design novel, safe, and effective therapies that help more people, faster, and at a lower cost. 

Fri, 20 Oct 2023

12:00 - 13:00

The Artin-Schreier Theorem

James Taylor
(University of Oxford)
Abstract

Typically, the algebraic closure of a non-algebraically closed field F is an infinite extension of F. However, this doesn't always have to happen: for example consider $\mathbb{R}$ inside $\mathbb{C}$. Are there any other examples? Yes: for example you can consider the index two subfield of the algebraic numbers, defined by intersecting with $\mathbb{R}$. However this is still similar to the first example: the degree of the extension is two, and we extract a square root of $-1$ to obtain the algebraic closure. The Artin-Schreier Theorem tells us that amazingly this is always the case: if $F$ is a field for which the algebraic closure is a non trivial finite extension $L$, then this forces F to have characteristic 0, L is degree two over $F$, and $L = F(i)$ for some $i$ with $i^2 = -1$. I.e. all such extensions "look like" $\mathbb{C} / \mathbb{R}$. In this expository talk we will give an overview of the proof of this theorem, and try to get some feeling for why this result is true.

 

Thu, 19 Oct 2023
16:00
Lecture Room 4, Mathematical Institute

Detecting Lead-Lag Relationships in Stock Returns and Portfolio Strategies

Qi Jin
Abstract

We propose a method to detect linear and nonlinear lead-lag relationships in stock returns.  Our approach uses pairwise Lévy-area and cross-correlation of returns to rank the assets from leaders to followers. We use the rankings to construct a portfolio that longs or shorts the followers based on the previous returns of the leaders, and the stocks are ranked every time the portfolio is rebalanced. The portfolio also takes an offsetting position on the SPY ETF so that the initial value of the portfolio is zero. Our data spans from 1963 to 2022 and we use an average of over 500 stocks to construct portfolios for each trading day. The annualized returns of our lead-lag portfolios are over  20%, and the returns outperform all lead-lag benchmarks in the literature. There is little overlap between the leaders and the followers we find and those that are reported in previous studies based on market capitalization, volume traded, and intra-industry relationships. Our findings support the slow information diffusion hypothesis; i.e., portfolios rebalanced once a day consistently outperform the bidiurnal, weekly, bi-weekly, tri-weekly, and monthly rebalanced portfolios.

Thu, 19 Oct 2023
16:00
L5

Siegel modular forms and algebraic cycles

Aleksander Horawa
(Oxford University)
Abstract

(Joint work with Kartik Prasanna)

Siegel modular forms are higher-dimensional analogues of modular forms. While each rational elliptic curve corresponds to a single holomorphic modular form, each abelian surface is expected to correspond to a pair of Siegel modular forms: a holomorphic and a generic one. We propose a conjecture that explains the appearance of these two forms (in the cohomology of vector bundles on Siegel modular threefolds) in terms of certain higher algebraic cycles on the self-product of the abelian surface. We then prove three results:
(1) The conjecture is implied by Beilinson's conjecture on special values of L-functions. Amongst others, this uses a recent analytic result of Radzwill-Yang about non-vanishing of twists of L-functions for GL(4).
(2) The conjecture holds for abelian surfaces associated with elliptic curves over real quadratic fields.
(3) The conjecture implies a conjecture of Prasanna-Venkatesh for abelian surfaces associated with elliptic curves over imaginary quadratic fields.