Past

Biomedical research and clinical practice rely on complex and multimodality

datasets for the characterisation of human organs in health and disease. In

computational biomedicine, we often argue that multiscale computational

models are and will be increasingly required as tools for data integration,

for probing the established knowledge of physiological systems, and for

predictions of the effects of therapies and disease. But what has

computational biomedicine delivered so far? This presentation will describe

successes, failures and future directions of computational models in

cardiac research from basic to translational science.

I spent a number of years trading government bonds and interest-rate derivatives for Barclays Capital. This included the period of the financial crisis, and I was a colleague of some of the Barclays traders charged with fraud related to LIBOR rate manipulation. I will present a some examples of common trading scenarios, and some of the ethical issues these might raise for quants.
 

Let A be an abelian variety over the function field K of a curve over a finite field of characteristic p>0. We shall show that the group A(K^{p^{-\infty}}) is finitely generated, unless severe restrictions are put on the geometry of A. In particular, we shall show that if A is ordinary and has a point of bad reduction then A(K^{p^{-\infty}}) is finitely generated. This result can be used to give partial answers to questions of Scanlon, Ziegler, Esnault, Voloch and Poonen.

Conventional neutron reflection is a very powerful tool to characterise surfactants, polymers and other materials at the solid/liquid and air/liquid interfaces. Usually the analysis considers molecular layers with coherent addition of reflected waves that give the resultant reflected intensity. In this short workshop talk I will illustrate recent developments in this approach to address a wide variety of challenges of academic and commercial interest. Specifically I will introduce the challenges of using substrates that are thick on the coherence lengthscale of the radiation and the issues that brings in the structural analysis. I also invite the audience to consider if there may be some mathematical analysis that might lead us to exploit this incoherence to optimise our analysis. In particular, facilitating the removal of the 'background substrate contribution' to help us focus on the adsorbed layers of most interest.

I will review the notion of classifying topos of a first-order (geometric) theory and explain the central role enjoyed by theories of presheaf type (i.e. classified by a presheaf topos) in the context of the topos-theoretic investigation of the model theory of geometric theories. After presenting a few main results and characterizations for theories of presheaf type, I will illustrate the generality of the point of view provided by this class of theories by discussing a topos-theoretic framework unifying and generalizing Fraissé’s construction in model theory and topological Galois theory and leading to an approach to the problem of the independence from l of l-adic cohomology.

In 2016, Habegger and Pila published a proof of the Zilber-Pink conjecture for curves in abelian varieties (all defined over $\mathbb{Q}^{\rm alg}$). Their article also contained a proof of the same conjecture for a product of modular curves that was conditional on a strong arithmetic hypothesis. Both proofs were extensions of the Pila-Zannier strategy based in o-minimality that has yielded many results in this area. In this talk, we will explain our generalisation of the strategy to the Zilber-Pink conjecture for any Shimura variety. This is joint work with J. Ren.

Floer (co)homology, invariant which recovers periodic orbits of a Hamiltonian system, is the central topic of symplecic topology at present. Its analogue for open symplecic manifolds is called symplectic (co)homology. Our goal is to compute this invariant for big family of spaces called Nakajima's Quiver Varieties, spaces obtained as hyperkahler quotients of representation spaces of quivers.
 

Considerable attention has been recently focused on the study of muscle tissues viewed as prototypes of new materials that can actively generate stresses. The intriguing mechanical properties of such systems can be linked to hierarchical internal architecture. To complicate matters further, they are driven internally by endogenous mechanisms supplying energy and maintaining non-equilibrium.  In this talk we review the principal mechanisms of force generation in muscles and discuss the adequacy of the available mathematical models.

We  study  the  concept  of   financial  bubble  under model uncertainty.
We suppose the agent to be endowed with a family Q of local martingale measures for  the  underlying  discounted  asset  price. The priors are allowed to be mutually singular to each other.
One fundamental issue is the definition of a well-posed concept of robust fundamental value of a given  financial asset.
Since in this setting we have no linear pricing system, we choose to describe robust fundamental values through superreplication prices.
To this purpose, we investigate a dynamic version of robust superreplication, which we use
to  introduce  the  notions  of  bubble  and  robust  fundamental  value  in  a  consistent way with the existing literature in the classical case of one prior.

This talk is based on the works [1] and [2].

[1] Biagini, F. , Föllmer, H. and Nedelcu, S. Shifting martingale measures
and the slow birth of a bubble as a submartingale, Finance and
Stochastics: Volume 18, Issue 2, Page 297-326, 2014.

[2] Biagini, F., Mancin, J.,
Financial Asset Price Bubbles under Model 
Uncertainty, Preprint, 2016.

Structural optimization can be interpreted as the attempt to find the best mechanical structure to support specific load cases respecting some possible constraints. Within this context, topology optimization aims to obtain the connectivity, shape and location of voids inside a prescribed structural design domain. The methods for the design of stiff lightweight structures are well established and can already be used in a specific range of industries where such structures are important, e.g., in aerospace and automobile industries.

In this seminar, we will go through the basic engineering concepts used to quantify and analyze the computational models of mechanical structures. After presenting the motivation, the methods and mathematical tools used in structural topology optimization will be discussed. In our method, an implicit level set function is used to describe the structural boundaries. The optimization problem is approximated by linearization of the objective and constraint equations via Taylor’s expansion. Shape sensitivities are used to evaluate the change in the structural performance due to a shape movement and to feed the mathematical optimiser in an iterative procedure. Recent developments comprising multiscale and Multiphysics problems will be presented and a specific application proposal including acoustic-structure interaction will be discussed.

We determine the hydrodynamic limit of some kinetic equations with either stochastic Vlasov force term or stochastic collision kernel. We obtain stochastic second-order parabolic equations at the limit. In the regime we consider, we also observe (or do not observe) some phenomena of enhanced diffusion. Joint works with Nils Caillerie, Arnaud Debussche, Martina Hofmanová.
 

We discuss a recent preprint by Aschenbrenner, Khélif, Naziazeno and
Scanlon, giving a positive solution to the ring-analogue of Pop's
problem on elementary equivalence vs isomorphism. 

For every $\epsilon>0$ does there exist some $n\in\mathbb{N}$ and a bijection $f:\mathbb{Z}_n\to\mathbb{Z}_n$ such that $f(x+1)=2f(x)$ for at least $(1-\epsilon)n$ elements of $\mathbb{Z}_n$ and $f(f(f(f(x))))=(x)$ for all $x\in\mathbb{Z}_n$? I will discuss this question and its relation to an important open problem in the theory of countable discrete groups.

Coisotropic submanifolds arise naturally in symplectic geometry as level sets of moment maps and in algebraic geometry in the context of normal crossing divisors. In examples, the Marsden-Weinstein quotient or (Fano) complete intersections are often uniruled. 
We show that under natural geometric assumptions on a coisotropic submanifold, the symplectic quotient of the coisotropic is always geometrically uniruled. 
I will explain how to assign a Lagrangian and a hypersurface to a fibered, stable coisotropic C. The Lagrangian inherits a fibre bundle structure from C, the hypersurface captures the generalised Reeb dynamics on C. To derive the result, we then adapt and apply techniques from Lagrangian Floer theory and symplectic field theory.
This is joint work with Jonny Evans.
 

Many extremal results on cycles use what may be called BFS method, where a breath first search tree is used as a skeleton to build desired structures. A well-known example is the Bondy-Simonovits theorem that every n-vertex graph with more than 100kn^{1+1/k} edges contains an even cycle of length 2k. The standard BFS method, however, is not easily applicable for supersaturation problems where one wishes to show the existence of many copies of a given  subgraph. The method is also not easily applicable in the hypergraph setting.

In this talk, we focus on some variants of the standard BFS method. We use one of these in conjunction with some useful general reduction theorems that we develop to establish the supersaturation of loose (linear) even cycles in linear hypergraphs. This extends Simonovits' supersaturation theorem on even cycles in graphs. This is joint work with Liana Yepremyan.

If time allows, we will also discuss another variant (joint with Jie Ma) used in the study of Berge cycles of consecutive lengths in hypergraphs.

Heckman introduced N operators on the space of polynomials in N variables, such that these operators form a covariant set relative to permutations of the operators and variables, and such that Jack symmetric polynomials are eigenfunctions of the power sums of these operators. We introduce the analogues of these N operators for Macdonald symmetric polynomials, by using Cherednik operators. The latter operators pairwise commute, and Macdonald polynomials are eigenfunctions of their power sums. We compute the limits of our operators at N → ∞ . These limits yield a Lax operator for Macdonald symmetric functions. This is a joint work with Evgeny Sklyanin.

What's the continuous analog of randn?  In recent months I've been exploring such questions with Abdul-Lateef Haji-Ali and other members of the Chebfun team, and Chebfun now has commands randnfun, randnfun2, randnfunsphere, and randnfundisk.  These are based on finite Fourier series with random coefficients, and interesting questions arise in the "white noise" limit as the lengths of the series approaches infinity and as random ODEs become stochastic DEs.    This work is at an early stage and we are grateful for input from stochastic experts at Oxford and elsewhere.

Multi-agent systems in nature oftentimes exhibit emergent behaviour, i.e. the formation of patterns in the absence of a leader or external stimuli such as light or food sources. We present a non-local two species crossinteraction model with cross-diffusion and explore its long-time behaviour. We observe a rich zoology of behaviours exhibiting phenomena such as mixing and/or segregation of both species and the formation of travelling pulses.

 Locality is not expected to be a fundamental aspect of a full theory of quantum gravity; it should be emergent in an appropriate semiclassical limit.  In the context of general holography, I'll define a new construct - the causal state - which provides a necessary and sufficient condition for a boundary state to have a holographic semiclassical dual causal geometry (and thus be "local").  This definition illuminates some general features of holographic quantum gravity: for instance, I'll show that the emergence of locality is "all or nothing" in the sense that it exhibits features of quantum error correction and quantum secret sharing.  In the special case of AdS/CFT, I'll also argue that the causal state is the natural boundary dual to the so-called causal wedge of a region. 

Part of the series "What do historians of mathematics do?"  
In the last year of 14th century, a French mathematician/geometer Jean Mignot, was called from Paris to help with the construction of the Cathedral of Milan. Thus was created one of the most famous stories about how mathematics literally supports great works of art, helping them stand the test of time. This talk will look at some patterns that begin to become apparent in the investigations of the relationship between architecture and mathematics and the creativity that is common to the pursuit of both. I will present the case on how this may matter to someone who is interested in the history of mathematics. To make this more intelligible, I will partly talk also of my personal journey in investigating this relationship and the issues I have researched and written about, and how these in turn changed my view of the nature of mathematics education. 

Various concepts of weak solution have been suggested for the fundamental equations of fluid dynamics over the last few decades. However, such weak solutions may be non-unique, or at least their uniqueness is unknown. Nevertheless, a conditional notion of uniqueness, the so-called weak-strong uniqueness, can be established in various situations. We present some recent results, both positive and negative, on weak-strong uniqueness in the realm of incompressible and compressible fluid dynamics. Applications to the convergence of numerical schemes will be indicated.