Linus Schumacher

Title 

From modelling cell migration to inferring cell state transition dynamics


Abstract 

In this talk I will tell the story of how my work with Philip Maini set me on a path to some of the projects I now pursue in my own group. I will briefly recap our work on modelling neural crest cell migration, and how this sparked an interest in cell population heterogeneity, its effect on collective behaviour, and how to detect this in data. I will highlight work on measuring heterogeneity in collective cell migration, and modelling with discrete vs. continuous cell states, before showing recent work on bayesian inference of cell state transition rates in populations of pluripotent stem cells.

 

Short bio

Linus obtained his D.Phil. at the Wolfson Centre for Mathematical Biology, Oxford, after which he held postdoctoral positions at Oxford and Imperial College London. For his undergraduate he read Natural Sciences at the University of Cambridge. In 2018, he moved to the Centre for Regenerative Medicine at the University of Edinburgh to start his own research group.

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