Inferring parameters for a lattice-free model of cell migration and proliferation using experimental data
Browning, A McCue, S Binny, R Plank, M Shah, E Simpson, M
Author response: Quantitative analysis of tumour spheroid structure
Browning, A Sharp, J Murphy, R Gunasingh, G Lawson, B Burrage, K Haass, N Simpson, M (19 Nov 2021)
Rapid Optical Clearing for High-Throughput Analysis of Tumour Spheroids
Gunasingh, G Browning, A Haass, N
Rapid Optical Clearing for High-Throughput Analysis of Tumour Spheroids
Gunasingh, G Browning, A Haass, N
Rapid Optical Clearing for Semi-High-Throughput Analysis of Tumor Spheroids
Gunasingh, G Browning, A Haass, N Journal of Visualized Experiments issue 186 (23 Aug 2022)
Mon, 19 May 2025
16:30
L4

Weak solutions for the Navier-Stokes system for a compressible fluid with non-isotropic viscous-stress tensor.

Cosmin Burtea
(Université Paris Cité)
Abstract

When dealing with PDEs arising in fluid mechanics, bounded-energy weaksolutions are, in many cases, the only type of solutions for which one can guarantee global existence without imposing any restrictions on the size of the initial data or forcing terms. Understanding how to construct such solutions is also crucial for designing stable numerical schemes.

In this talk, we will explain the strategy for contructing weak solutions for the Navier-Stokes system for viscous compressible flows, emphasizing the difficulties encountered in the case of non-isotropic viscous stress tensors. In particular, I will present some results obtained in collaboration with Didier Bresch and Maja Szlenk.

Mon, 12 May 2025
16:30
L4

Viscoelastic models for tumour growth

Dennis Trautwein
(Uni-Regensburg)
Abstract

In this talk, we present a mathematical model for tumour growth that incorporates viscoelastic effects. Starting from a basic system of PDEs, we gradually introduce the relevant biological and physical mechanisms and explain how they are integrated into the model. The resulting system features a Cahn--Hilliard type equation for the tumour cells coupled to a convection-reaction-diffusion equation for a nutrient species, and a viscoelastic subsystem for an internal velocity.
Key biological processes such as active transport, apoptosis, and proliferation are modeled via source and sink terms as well as cross-diffusion effects. The viscoelastic behaviour is described using the Oldroyd-B model, which is based on a multiplicative decomposition of the deformation gradient to account for elasticity alongside growth and relaxation effects.
We will highlight several of these effects through numerical simulations.
Moreover, we discuss the main analytical and numerical challenges. Particular focus will be given to the treatment of source and cross-diffusion terms, the elastic energy density, and the difficulties arising from the viscoelastic subsystem. The main analytical result is the global-in-time existence of weak solutions in two spatial dimensions, under the assumption of additional viscoelastic diffusion in the Oldroyd-B equation.
This work is based on joint work with Harald Garcke (University of Regensburg, Germany) and Balázs Kovács (University of Paderborn, Germany).

Mon, 28 Apr 2025
16:30
L4

Wave localization at subwavelength scales

Habib Amari
(ETH)
Abstract

Systems of high-contrast resonators can be used to control and manipulate wave-matter interactions at scales that are much smaller than the operating wavelengths. The aim of this talk is to review recent studies of ordered and disordered systems of subwavelength resonators and to explain some of their topologically protected localization properties. Both reciprocal and non-reciprocal systems will be considered.
 

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