OCCAM Group Meeting
Abstract
- Jean Charles Seguis - The fictitious domain method applied to hybrid simulations in biology
- Chris Farmer - Data assimilation and parameter estimation
- Mark Curtis - Stokes' flow, singularities and sperm
Successful navigation through a complicated and evolving environment is a fundamental task carried out by an enormous range of organisms, with migration paths staggering in their length and intricacy. Selecting a path requires the detection, processing and integration of a myriad of cues drawn from the surrounding environment and in many instances it is the intrinsic orientation of the environment that provides a valuable navigational aid.
In this talk I will describe the use of transport models to describe migration in oriented environments, and demonstrate the scaling approaches that allow us to derive macroscopic models for movement.
I will illustrate the methods through a number of apposite examples, including the migration of cells in the extracellular matrix, the macroscopic growth of brain tumours and the movement of wolves in boreal forest.
Models for invasions track the front of an expanding wave of population density. They take the form of parabolic partial differential equations and related integral formulations. These models can be used to address questions ranging from the rate of spread of introduced invaders and diseases to the ability of vegetation to shift in response to climate change.
In this talk I will focus on scientific questions that have led to new mathematics and on mathematics that have led to new biological insights. I will investigate the mathematical and empirical basis for multispecies invasions and for accelerating invasion waves.
We define a set of nonlocal operators and develop a nonlocal vector calculus that mimics the classical differential vector calculus. Included are the definitions of nonlocal divergence, gradient, and curl operators and the derivation of nonlocal integral theorems and identities. We indicate how, through certain limiting processes, the nonlocal operators are connected to their differential counterparts. The nonlocal operators are shown to appear in nonlocal models for diffusion and in the nonlocal, spatial derivative free, peridynamics continuum model for solid mechanics. We show, for example, that unlike elliptic partial differential equations, steady state versions of the nonlocal models do not necessary result in the smoothing of data. We also briefly consider finite element methods for nonlocal problems, focusing on solutions containing jump discontinuities; in this setting, nonlocal models can lead to optimally accurate approximations.