Disease transmission and rumour spreading are ubiquitous in social and technological networks. In this talk, we will present our last results on the modelling of rumour and disease spreading in multilayer networks. We will derive analytical expressions for the epidemic threshold of the susceptible-infected-susceptible (SIS) and susceptible-infected-recovered dynamics, as well as upper and lower bounds for the disease prevalence in the steady state for the SIS scenario. Using the quasistationary state method, we numerically show the existence of disease localization and the emergence of two or more susceptibility peaks in a multiplex network. Moreover, we will introduce a model of epidemic spreading with awareness, where the disease and information are propagated in different layers with different time scales. We will show that the time scale determines whether the information awareness is beneficial or not to the disease spreading.