The talk will begin with an introduction to the science of what determines the behaviour of a liquid on a on a surface and giving an overview of some of the different theories that can be used to describe the shape and structure of the liquid in the drop. These include microscopic density functional theory (DFT), which describes the liquid structure on the scale of the individual liquid molecules, and mesoscopic thin film equation (PDE) and kinetic Monte-Carlo models. A DFT based method for calculating the binding potential ?(h) for a film of liquid on a solid surface, where h is the thickness of the liquid film, will be presented. The form of ?(h) determines whether or not the liquid wets the surface. Calculating drop profiles using both DFT and also from inputting ?(h) into the mesoscopic theory and comparing quantities such as the contact angle and the shape of the drops, we find good agreement between the two methods, validating the coarse-graining. The talk will conclude with a discussion of some recent work on modelling evaporating drops with applications to inkjet printing.