Abstract: This talk introduces the ZX-calculus, a powerful graphical language for reasoning about quantum computations. I will start with an overview of process theories, a general framework for describing how processes act upon different types of information. I then focus on the process theory of quantum circuits, where each function (or gate) is a unitary linear transformation acting upon qubits. The ZX-calculus simplifies the set of available gates in terms of two atomic operations: Z and X spiders, which generalize rotations around the Z and X axes of the Bloch sphere. I demonstrate how to translate quantum circuits into ZX-diagrams and how to simplify ZX diagrams using a set of seven equivalences. Through examples and illustrations, I hope to convey that the ZX-calculus provides an intuitive and powerful tool for reasoning about quantum computations, allowing for the derivation of equivalences between circuits. By the end of the talk listeners should be able to understand equations written in the ZX-calculus and potentially use them in their own work.

Six-functor formalisms are ubiquitous in mathematics, and I will start this talk by giving a quick introduction to them. A three-functor formalism is, as the name suggests, (the better) half of a six-functor formalism. I will discuss what it means for such a three-functor formalism to be unitary, and why commutative Von Neumann algebras (and hence, by the Gelfand-Naimark theorem, measure spaces) admit a unitary three-functor formalism that can be viewed as mixing sheaf theory with functional analysis. Based on joint work with André Henriques.

Blood vessels are among the most vital structures in the human body, forming intricate networks that connect and support various organ systems. Remarkably, during early embryonic development—before any blood vessels are visible—their precursor cells are arranged in stereotypical patterns throughout the embryo. We hypothesize that these patterns guide the directional growth and fusion of precursor cells into hollow tubes formed from initially solid clusters. Further analysis of cells within these clusters reveals unique organization that may influence their differentiation into endothelial and blood cells. In this work, I revisit the problem of pattern formation through the lens of active matter physics, using both developing embryonic systems and in vitro cell culture models where similar patterns are observed during tissue budding. These different systems exhibit similar patterning behavior, driven by changes in cellular activity, adhesion and motility.

Microbial communities contain many evolving and interacting bacteria, which makes them complex systems that are difficult to understand and predict. We use theory – including game theory, agent-based modelling, ecological network theory and metabolic modelling - and combine this with experimental work to understand what it takes for bacteria to succeed in diverse communities. One way is to actively kill and inhibit competitors and we study the strategies that bacteria use in toxin-mediated warfare. We are now also using our approaches to understand the human gut microbiome and its key properties including ecological stability and the ability to resist invasion by pathogens (colonization resistance). Our ultimate goal is to both stabilise microbiome communities and remove problem species without the use of antibiotics.