University of Southampton

The significance of the effects of non-healing wounds has been the topic of many research papers and lectures during the last 25 years. Efforts have been made to understand the effects of long-standing venous hypertension, diabetes, the prevalence of wounds in such conditions with as well as the difficulties faced in managing such wounds with some success. Successful efforts to define standard care regimes have also been made. However, attempts to introduce innovative therapy have been much less successful. Is this merely because we have not understood the intricacies of the problem? And would system based modelling be an untried technique?

Venous ulcers are the majority of lower extremity wounds, and a clinical challenge. A previously developed model of venous ulcers permits some understanding of why compression bandaging is successful but fails to accommodate complications such as exudate and infection. Could this experimental model be improved by system based modelling?

Chronic wounds need to be modelled however the needs for such models should be examined in order that the outcome permits advances in our thinking as well in clinical management.

In this talk I will look at a definition of the energy-momentum for the dynamical horizon of a black hole. The talk will begin by examining the role of a special class of observers at null infinity determined by Bramson's concept of frame alignment. It is shown how this is given in terms of asymptotically constant spinor fields and how this framework may be used together with the Nester-Witten two form to give a definition of the Bondi mass at null infinity.

After reviewing Ashtekar's concept of an isolated horizon we will look at the propagation of spinor fields and show how to introduce spinor fields for the horizon which play the role of the asymptotically constant spinor fields at null infinity, giving a concept of alignment of frames on the horizon. It turns out that the equations satisfied by these spinor fields give precisely the Dougan-Mason holomorphic condition on the cross sections of the horizon, together with a simple propagation equation along the generators. When combined with the Nester-Witten 2-form these equations give a quasi-local definition of the mass and momentum of the black hole, as well as a formula for the flux across the horizon. These ideas are then generalised to the case of a dynamical horizon and the results compared to those obtained by Ashtekar as well as to the known answers for a number of exact solutions.