We shall explain how to give substance to an old dream of Tits, to invent exotic new zeta functions, and discover the skeleton of algebraic varieties (toric manifolds and tropical geometry).
An emerging set of methods enables an experimental dialogue with biological systems composed of many interacting cell types---in particular, with neural circuits in the brain. These methods are sometimes called “optogenetic” because they employ light-responsive proteins (“opto-“) encoded in DNA (“-genetic”). Optogenetic devices can be introduced into tissues or whole organisms by genetic manipulation and be expressed in anatomically or functionally defined groups of cells. Two kinds of devices perform complementary functions: light-driven actuators control electrochemical signals; light-emitting sensors report them. Actuators pose questions by delivering targeted perturbations; sensors (and other measurements) signal answers. These catechisms are beginning to yield previously unattainable insight into the organization of neural circuits, the regulation of their collective dynamics, and the causal relationships between cellular activity patterns and behavior.
We shall report on the use of algebraic geometry for the calculation of Feynman amplitudes (work of Bloch, Brown, Esnault and Kreimer). Or how to combine Grothendieck's motives with high energy physics in an unexpected way, radically distinct from string theory.
\ \ In 1939 Rademacher derived a conditionally convergent series expression for the modular j-invariant, and used this expression---the first Rademacher sum---to verify its modular invariance. We may attach Rademacher sums to other discrete groups of isometries of the hyperbolic plane, and we may ask how the automorphy of the resulting functions reflects the geometry of the group in question.
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\ \ In the case of a group that defines a genus zero quotient of the hyperbolic plane the relationship is particularly striking. On the other hand, of the common features of the groups that arise in monstrous moonshine, the genus zero property is perhaps the most elusive. We will illustrate how Rademacher sums elucidate this phenomena by using them to formulate a characterization of the discrete groups of monstrous moonshine.
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\ \ A physical interpretation of the Rademacher sums comes into view when we consider black holes in the context of three dimensional quantum gravity. This observation, together with the application of Rademacher sums to moonshine, amounts to a new connection between moonshine, number theory and physics, and furnishes applications in all three fields.
Many problems from combinatorics, number theory, quantum field theory and topology lead to power series of a special kind called q-hypergeometric series. Sometimes, like in the famous Rogers-Ramanujan identities, these q-series turn out to be modular functions or modular forms. A beautiful conjecture of W. Nahm, inspired by quantum theory, relates this phenomenon to algebraic K-theory.
In a different direction, quantum invariants of knots and 3-manifolds also sometimes seem to have modular or near-modular properties, leading to new objects called "quantum modular forms".