14:15
Closed Ricci Flows with Singularities Modeled on Asymptotically Conical Shrinkers
Abstract
Shrinking Ricci solitons are Ricci flow solutions that self-similarly shrink under the flow. Their significance comes from the fact that finite-time Ricci flow singularities are typically modeled on gradient shrinking Ricci solitons. Here, we shall address a certain converse question, namely, “Given a complete, noncompact gradient shrinking Ricci soliton, does there exist a Ricci flow on a closed manifold that forms a finite-time singularity modeled on the given soliton?” We’ll discuss work that shows the answer is yes when the soliton is asymptotically conical. No symmetry or Kahler assumption is required, and so the proof involves an analysis of the Ricci flow as a nonlinear degenerate parabolic PDE system in its full complexity. We’ll also discuss applications to the (non-)uniqueness of weak Ricci flows through singularities.
14:00
Stochastic methods for derivative free optimization
Abstract
Numerical optimization is an indispensable tool of modern data analysis, and there are many optimization problems where it is difficult or impossible to compute the full gradient of the objective function. The field of derivative free optimization (DFO) addresses these cases by using only function evaluations, and has wide-ranging applications from hyper-parameter tuning in machine learning to PDE-constrained optimization.
We present two projects that attempt to scale DFO techniques to higher dimensions. The first method converges slowly but works in very high dimensions, while the second method converges quickly but doesn't scale quite as well with dimension. The first-method is a family of algorithms called "stochastic subspace descent" that uses a few directional derivatives at every step (i.e. projections of the gradient onto a random subspace). In special cases it is related to Spall's SPSA, Gaussian smoothing of Nesterov, and block-coordinate descent. We provide convergence analysis and discuss Johnson-Lindenstrauss style concentration. The second method uses conventional interpolation-based trust region methods which require large ill-conditioned linear algebra operations. We use randomized linear algebra techniques to ameliorate the issues and scale to larger dimensions; we also use a matrix-free approach that reduces memory issues. These projects are in collaboration with David Kozak, Luis Tenorio, Alireza Doostan, Kevin Doherty and Katya Scheinberg.
13:00
Holomorphic twist and Confinement
Abstract
I will describe a procedure, known as holomorphic twist, to isolate protected quantities in supersymmetric quantum field theories. The resulting theories are holomorphic, interacting and have infinite dimensional symmetries, analogous to the holomorphic half of a 2D CFT. I will explain how to study quantum corrections to these symmetries and other higher operations.
As a surprise, we find a novel UV manifestation of
confinement, dubbed "holomorphic confinement," in the example of pure
SU(N) super Yang-Mills.
North Meets South
Abstract
Ilia Smilga
Margulis spacetimes and crooked planes
We are interested in the following problem: which groups can act
properly on R^n by affine transformations, or in other terms, can occur
as a symmetry group of a "regular affine tiling"? If we additionally
require that they preserve a Euclidean metric (i.e. act by affine
isometries), then these groups are well-known: they all contain a
finite-index abelian subgroup. If we remove this requirement, a
surprising result due to Margulis is that the free group can act
properly on R^3. I shall explain how to construct such an action.
Charles Parker
Unexpected Behavior in Finite Elements for Linear Elasticity
One of the first problems that finite elements were designed to approximate is the small deformations of a linear elastic body; i.e. the 2D/3D version of Hooke's law for springs from elementary physics. However, for nearly incompressible materials, such as rubber, certain finite elements seemingly lose their approximation power. After briefly reviewing the equations of linear elasticity and the basics of finite element methods, we will spend most of the time looking at a few examples that highlight this unexpected behavior. We conclude with a theoretical result that (mostly) explains these findings.
Topological Data Analytic Frameworks for Discovering Biophysical Signatures in 3D Shapes and Images
Lorin Crawford is the RGSS Assistant Professor of Biostatistics at Brown University. He is affiliated with the Center for Statistical Sciences, Center for Computational Molecular Biology, and the Robert J. and Nancy D. Carney Institute for Brain Science.
14:30
CDT in Mathematics of Random Systems October Workshop 2022
Abstract
2:30 -3.00 Will Turner (CDT Student, Imperial College London)
Topologies on unparameterised path space
The signature of a path is a non-commutative exponential introduced by K.T. Chen in the 1950s, and appears as a central object in the theory of rough paths developed by T. Lyons in the 1990s. For continuous paths of bounded variation, the signature may be realised as a sequence of iterated integrals, which provides a succinct summary for multimodal, irregularly sampled, time-ordered data. The terms in the signature act as an analogue to monomials for finite dimensional data: linear functionals on the signature uniformly approximate any compactly supported continuous function on unparameterised path space (Levin, Lyons, Ni 2013). Selection of a suitable topology on the space of unparameterised paths is then key to the practical use of this approximation theory. We present new results on the properties of several candidate topologies for this space. If time permits, we will relate these results to two classical models: the fixed-time solution of a controlled differential equation, and the expected signature model of Levin, Lyons, and Ni. This is joint work with Thomas Cass.
3.05 -3.35 Ross Zhang (CDT Student, University of Oxford)
Random vortex dynamics via functional stochastic differential equations
The talk focuses on the representation of the three-dimensional (3D) Navier-Stokes equations by a random vortex system. This new system could give us new numerical schemes to efficiently approximate the 3D incompressible fluid flows by Monte Carlo simulations. Compared with the 2D Navier-Stokes equation, the difficulty of the 3D Navier-Stokes equation lies in the stretching of vorticity. To handle the stretching term, a system of stochastic differential equations is coupled with a functional ordinary differential equation in the 3D random vortex system. Two main tools are developed to derive the new system: the first is the investigation of pinned diffusion measure, which describes the conditional distribution of a time reversal diffusion, and the second is a forward-type Feynman Kac formula for nonlinear PDEs, which utilizes the pinned diffusion measure to delicately overcome the time reversal issue in PDE. Although the main focus of the research is the Navier-stokes equation, the tools developed in this research are quite general. They could be applied to other nonlinear PDEs as well, thereby providing respective numerical schemes.
3.40 - 4.25pm Dr Cris Salvi (Imperial College London)
Signature kernel methods
Kernel methods provide a rich and elegant framework for a variety of learning tasks including supervised learning, hypothesis testing, Bayesian inference, generative modelling and scientific computing. Sequentially ordered information often arrives in the form of complex streams taking values in non-trivial ambient spaces (e.g. a video is a sequence of images). In these situations, the design of appropriate kernels is a notably challenging task. In this talk, I will outline how rough path theory, a modern mathematical framework for describing complex evolving systems, allows to construct a family of characteristic kernels on pathspace known as signature kernels. I will then present how signature kernels can be used to develop a variety of algorithms such as two-sample hypothesis and (conditional) independence tests for stochastic processes, generative models for time series and numerical methods for path-dependent PDEs.
4.30 Refreshments
Emergent digital biocomputation through spatial diffusion and engineered bacteria
Abstract
Building computationally capable biological systems has long been an aim of synthetic biology. The potential utility of bio-computing devices ranges from biosafety and environmental applications to diagnosis and personalised medicine. Here we present work on the design of bacterial computers which use spatial patterning to process information. A computer is composed of a number of bacterial colonies which, inspired by patterning in embryo development, communicate using diffusible morphogen-like signals. A computation is programmed into the overall physical arrangement of the system by arranging colonies such that the resulting diffusion field encodes the desired function, and the output is represented in the spatial pattern displayed by the colonies. We first mathematically demonstrate the simple digital logic capability of single bacterial colonies and show how additional structure is required to build complex functions. Secondly, inspired by electronic design automation, an algorithm for designing optimal spatial circuits computing two-level digital logic functions is presented, extending the capability of our system to complex digital functions without significantly increasing the biological complexity. We implement experimentally a proof-of-principle system using engineered Escherichia coli interpreting diffusion fields formed from droplets of an inducer molecule. Our approach will open up new ways to perform biological computation, with applications in synthetic biology, bioengineering and biosensing. Ultimately, these computational bacterial communities will help us explore information processing in natural biological systems.
Growth of Mod p Representations of p-adic Lie Groups
Abstract
The canonical dimension is a fundamental integer-valued invariant that is attached to mod p representations of p-adic Lie groups. I will explain why it is both an asymptotic measure of growth, and an algebraic quantity strongly related to Krull dimension. We will survey algebraic tools that can be applied in its calculation, and describe results spanning the last twenty years. I'll present a new theorem and suggest its possible significance for the mod p local Langlands programme.
InFoMM CDT Group Meeting
10:00
Dynamical ticket pricing for movies
Note: we would recommend to join the meeting using the Teams client for best user experience.
Abstract
Movie Me would like offer dynamical pricing for movie tickets, considering consumer’s demand for the movie, showtime and lead time before the show begins, such that the overall quantity of tickets sold is maximized. We encourage all interested party to join us and especially those interested in data science, optimization and mathematical finance.
16:00
Counting rational points on conics, and on Del Pezzo surfaces of degree 5
Abstract
If $Q(x_0,x_1,x_2)$ is a quadratic form, how many solutions, of size at most $B$, does $Q=0$ have? How does this depend on $Q$? We apply the answers to the surface $y_0 Q_0 +y_1 Q_1 = 0$ in $P^1 x P^2$. (Joint work with Dan Loughran.)
Merton's optimal investment problem with jump signals
Abstract
This talk presents a new framework for Merton’s optimal investment problem which uses the theory of Meyer $\sigma$-fields to allow for signals that possibly warn the investor about impending jumps. With strategies no longer predictable, some care has to be taken to properly define wealth dynamics through stochastic integration. By means of dynamic programming, we solve the problem explicitly for power utilities. In a case study with Gaussian jumps, we find, for instance, that an investor may prefer to disinvest even after a mildly positive signal. Our setting also allows us to investigate whether, given the chance, it is better to improve signal quality or quantity and how much extra value can be generated from either choice.
This talk is based on joint work with Peter Bank.
Domain decomposition training strategies for physics-informed neural networks [talk hosted by Rutherford Appleton Lab]
Abstract
Physics-informed neural networks (PINNs) [2] are a solution method for solving boundary value problems based on differential equations (PDEs). The key idea of PINNs is to incorporate the residual of the PDE as well as boundary conditions into the loss function of the neural network. This provides a simple and mesh-free approach for solving problems relating to PDEs. However, a key limitation of PINNs is their lack of accuracy and efficiency when solving problems with larger domains and more complex, multi-scale solutions.
In a more recent approach, Finite Basis Physics-Informed Neural Networks (FBPINNs) [1], the authors use ideas from domain decomposition to accelerate the learning process of PINNs and improve their accuracy in this setting. In this talk, we show how Schwarz-like additive, multiplicative, and hybrid iteration methods for training FBPINNs can be developed. Furthermore, we will present numerical experiments on the influence on convergence and accuracy of these different variants.
This is joint work with Alexander Heinlein (Delft) and Benjamin Moseley (Oxford).
References
1. [1] B. Moseley, A. Markham, and T. Nissen-Meyer. Finite basis physics- informed neural networks (FBPINNs): a scalable domain decomposition approach for solving differential equations. arXiv:2107.07871, 2021.
2. [2] M. Raissi, P. Perdikaris, and G. E. Karniadakis. Physics-informed neural networks: A deep learning framework for solving forward and inverse problems involving nonlinear partial differential equations. Journal of Computational Physics, 378:686–707, 2019.
Mathematrix: Support in the Maths Institute
Abstract
We will be joined by Charlotte Turner-Smith to discuss issues surrounding harassment and mental health, and how the department is helping to tackle these.
Swimming in complex fluids
Abstract
Many microorganisms must navigate strange biological environments whose physics are unique and counter-intuitive, with wide-ranging consequences for evolutionary biology and human health. Mucus, for instance, behaves like both a fluid and an elastic solid. This can affect locomotion dramatically, which can be highly beneficial (e.g. for mammalian spermatozoa swimming through cervical fluid) or extremely problematic (e.g. the Lyme disease spirochete B. burgdorferi swimming through the extracellular matrix of human skin). Mathematical modeling and numerical simulations continue to provide new fundamental insights about the biological world in and around us and point toward new possibilities in biomedical engineering. These complex fluid phenomena can either enhance or retard a microorganism's swimming speed, and can even change the direction of swimming, depending on the body geometry and the properties of the fluid. We will discuss analytical and numerical insights into swimming through model viscoelastic (Oldroyd-B) and liquid-crystalline (Ericksen-Leslie) fluids, with a special focus on the important and in some cases dominant roles played by the presence of nearby boundaries.
16:00
$\ell^2$ and profinite invariants
Abstract
We review a few instances in which the first $\ell^2$ Betti number of a group is a profinite invariant and we discuss some applications and open problems.
A tale of two balloons
Abstract
From each point of a Poisson point process start growing a balloon at rate 1. When two balloons touch, they pop and disappear. Will balloons reach the origin infinitely often or not? We answer this question for various underlying spaces. En route we find a new(ish) 0-1 law, and generalize bounds on independent sets that are factors of IID on trees. Joint work with Omer Angel and Gourab Ray.
Part of the Oxford Discrete Maths and Probability Seminar, held via Zoom. Please see the seminar website for details.
16:00
Chaotic tracial dynamics
Abstract
The classification by K-theory and traces of the category of simple, separable, nuclear, Z-stable C*-algebras satisfying the UCT is an extraordinary feat of mathematics. What's more, it provides powerful machinery for the analysis of the internal structure of these regular C*-algebras. In this talk, I will explain one such application of classification: In the subclass of classifiable C*-algebras consisting of those for which the simplex of tracial states is nonempty, with extremal boundary that is compact and has the structure of a connected topological manifold, automorphisms can be shown to be generically tracially chaotic. Using similar ideas, I will also show how certain stably projectionless C*-algebras can be described as crossed products.
Average degree and girth
Abstract
In 1983 Thomassen conjectured that every graph of sufficiently large average degree has a subgraph of large girth and large average degree. While this conjecture remains open, recent evidence suggests that something stronger might be true; perhaps the subgraph can be made induced when a clique and biclique are forbidden. We overview our proof for removing 4-cycles from $K_{t,t}$-free bipartite graphs. Moreover, we discuss consequences to tau-boundedness, which is an analog of chi-boundedness.
Part of the Oxford Discrete Maths and Probability Seminar, held via Zoom. Please see the seminar website for details.
On the asymptotic analysis of the Calogero-Painlevé systems and the Tracy-Widom$_\beta$ distribution for $\beta$=6
Abstract
The Calogero-Painlevé systems were introduced in 2001 by K. Takasaki as a natural generalization of the classical Painlevé equations to the case of the several Painlevé “particles” coupled via the Calogero type interactions. In 2014, I. Rumanov discovered a remarkable fact that a particular case of the Calogero– Painlevé II equation describes the Tracy-Widom distribution function for the general $\beta$-ensembles with the even values of parameter $\beta$. in 2017 work of M. Bertola, M. Cafasso , and V. Rubtsov, it was proven that all Calogero-Painlevé systems are Lax integrable, and hence their solutions admit a Riemann-Hilbert representation. This important observation has opened the door to rigorous asymptotic analysis of the Calogero-Painlevé equations which in turn yields the possibility of rigorous evaluation of the asymptotic behavior of the Tracy-Widom distributions for the values of $\beta$ beyond the classical $\beta =1, 2, 4$. In the talk these recent developments will be outlined with a special focus on the Calogero-Painlevé system corresponding to $\beta = 6$. This is a joint work with Andrei Prokhorov.
Seminar Cancelled
15:00
Rational curvature invariants of 2-dimensional complexes
Abstract
I will discuss some new invariants of 2-complexes. They are inspired by recent developments in the theory of one-relator groups, but also have the potential to unify the theories of many well-studied families including small-cancellation presentation complexes, CAT(0) 2-complexes and 3-manifold spines, in addition to the motivating examples of one-relator presentation complexes. The fundamental result is that these invariants are the extrema of explicit linear-programming problems, and in particular are rational, computable and realised. The definitions suggest a conjectural “map” of 2-complexes, which I will attempt to describe.
Some recent developments in high order finite element methods for incompressible flow
Abstract
14:00
Nonbacktracking spectral clustering of nonuniform hypergraphs
Note: we would recommend to join the meeting using the Zoom client for best user experience.
Abstract
Spectral methods offer a tractable, global framework for clustering in graphs via eigenvector computations on graph matrices. Hypergraph data, in which entities interact on edges of arbitrary size, poses challenges for matrix representations and therefore for spectral clustering. We study spectral clustering for arbitrary hypergraphs based on the hypergraph nonbacktracking operator. After reviewing the definition of this operator and its basic properties, we prove a theorem of Ihara-Bass type which allows eigenpair computations to take place on a smaller matrix, often enabling faster computation. We then propose an alternating algorithm for inference in a hypergraph stochastic blockmodel via linearized belief-propagation which involves a spectral clustering step, again using nonbacktracking operators. We provide proofs related to this algorithm that both formalize and extend several previous results. We pose several conjectures about the limits of spectral methods and detectability in hypergraph stochastic blockmodels in general, supporting these with in-expectation analysis of the eigeinpairs of our studied operators. We perform experiments with real and synthetic data that demonstrate the benefits of hypergraph methods over graph-based ones when interactions of different sizes carry different information about cluster structure.
Joint work with Nicole Eikmeier (Grinnell) and Jamie Haddock (Harvey Mudd).
14:00
Sums of squares in group algebras and vanishing of cohomology
Abstract
I will discuss algebraic conditions that for a given group guarantee or characterize the vanishing of cohomology in a given degree with coefficients in any unitary representation. These conditions will be expressed in terms positivity of certain elements over group algebras, where positivity is meant as being a sum of hermitian squares. I will explain how conditions like this can be used to give computer-assisted proofs of vanishing of cohomology.
16:00
Recasting Selmer Schemes
Abstract
The Chabauty-Kim method is an effective algorithm for finding the $S$-integral points of hyperbolic curves by directly using the hyperbolicity in group-cohomological arguments. Central objects in the theory are affine spaces known as a Selmer schemes. We'll introduce the CK method and Selmer schemes, and demonstrate some additional structures possessed by Selmer schemes which can aid in implementing the CK method.
15:30
Simple homotopy types of 4-manifolds
Abstract
Two CW-complexes are simple homotopy equivalent if they are related by a sequence of collapses and expansions of cells. It implies homotopy equivalent as is implied by homeomorphic. This notion proved extremely useful in manifold topology and is central to the classification of non-simply connected manifolds up to homeomorphism. I will present the first examples of two 4-manifolds which are homotopy equivalent but not simple homotopy equivalent, as well as in all higher even dimensions. The examples are constructed using surgery theory and the s-cobordism theorem, and are distinguished using methods from algebraic number theory and algebraic K-theory. I will also discuss a number of new directions including progress on classifying the possible fundamental groups for which examples exist. This is joint work with Csaba Nagy and Mark Powell.
Edwards-Wilkinson fluctuations for the Anisotropic KPZ in the weak coupling regime
Abstract
In this talk, we present recent results on an anisotropic variant of the Kardar-Parisi-Zhang equation, the Anisotropic KPZ equation (AKPZ), in the critical spatial dimension d=2. This is a singular SPDE which is conjectured to capture the behaviour of the fluctuations of a large family of random surface growth phenomena but whose analysis falls outside of the scope not only of classical stochastic calculus but also of the theory of Regularity Structures and paracontrolled calculus. We first consider a regularised version of the AKPZ equation which preserves the invariant measure and prove the conjecture made in [Cannizzaro, Erhard, Toninelli, "The AKPZ equation at stationarity: logarithmic superdiffusivity"], i.e. we show that, at large scales, the correlation length grows like t1/2 (log t)1/4 up to lower order correction. Second, we prove that in the so-called weak coupling regime, i.e. the equation regularised at scale N and the coefficient of the nonlinearity tuned down by a factor (log N)-1/2, the AKPZ equation converges to a linear stochastic heat equation with renormalised coefficients. Time allowing, we will comment on how some of the techniques introduced can be applied to other SPDEs and physical systems at and above criticality.
14:15
Hitchin representations and minimal surfaces in symmetric spaces
Abstract
Labourie proved that every Hitchin representation into PSL(n,R) gives rise to an equivariant minimal surface in the corresponding symmetric space. He conjectured that uniqueness holds as well (this was known for n=2,3), and explained that if true, then the Hitchin component admits a mapping class group equivariant parametrization as a holomorphic vector bundle over Teichmüller space.
In this talk, we will define Hitchin representations, Higgs bundles, and minimal surfaces, and give the background for the Labourie conjecture. We will then explain that the conjecture fails for n at least 4, and point to some future questions and conjectures.
Going All Round the Houses: Mathematics, Horoscopes and History before 1600
Abstract
To be a mathematicus in 15th- and 16th-century Europe often meant practising as an astrologer. Far from being an unwelcome obligation, or simply a means of paying the rent, astrology frequently represented a genuine form of mathematical engagement. This is most clearly seen by examining changing definitions of one of the key elements of horoscope construction: the astrological houses. These twelve houses are divisions of the zodiac circle and their character fundamentally affects the significance of the planets which occupy them at any particular moment in time. While there were a number of competing systems for defining the houses, one system was standard throughout medieval Europe. However, the 16th-century witnessed what John North referred to as a “minor revolution”, as a different technique first developed in the Islamic world but adopted and promoted by Johannes Regiomontanus became increasingly prevalent. My paper reviews this shift in astrological practice and investigates the mathematical values it represents – from aesthetics and geometrical representation to efficiency and computational convenience.
13:00
Decomposition and condensation defects in 3d
Abstract
Quantum field theories (QFTs) in d dimensions that posses a (d-1)-form symmetry are conjectured to decompose into disjoint “universes”, each of which is itself a (local and unitary) QFT. I will give an overview of our current understanding of decomposition, and then discuss how this phenomenon occurs in the fusion of condensation defects of certain 3d QFTs. This gives a “microscopic” explanation of why in these instances, the fusion coefficient can be taken as an integer rather than a general TQFT.
Maintaining your mental fitness as a graduate student or postdoc
Abstract
Academic research can be challenging and can bring with it difficulties in maintaining good mental health. This session will be led by Rebecca Reed, Mental Health First Aid (MHFA) Instructor, Meditation & Yoga Teacher and Personal Development Coach and owner of wellbeing company Siendo. Rebecca will talk about how we can maintain good mental fitness, recognizing good practices to ensure we avoid mental-health difficulties before they begin. We have deliberately set this session to be at the beginning of the academic year in this spirit. We will also talk about maintaining good mental health specifically in the academic community.
16:00
Selected aspects of the dynamical Kirchberg-Phillips theorem
Abstract
I will start this talk with a brief introduction and summary of the outcome of a joint work with James Gabe. An important special case of the main result is that for any countable discrete amenable group G, any two outer G-actions on stable Kirchberg algebras are cocycle conjugate precisely when they are equivariantly KK-equivalent. In the main body of the talk, I will outline the key arguments toward a special case of the 'uniqueness theorem', which is one of the fundamental ingredients in our theory: Suppose we have two G-actions on A and B such that B is a stable Kirchberg algebra and the action on B is outer and equivariantly O_2-absorbing. Then any two cocycle embeddings from A to B are approximately unitarily equivalent. If time permits, I will provide a (very rough) sketch of how this leads to the dynamical O_2-embedding theorem, which implies that such cocycle embeddings always exist in the first place.
Kan Extensions and Kan Ensembles in Machine Learning
Abstract
A common problem in data science is "use this function defined over this small set to generate predictions over that larger set." Extrapolation, interpolation, statistical inference and forecasting all reduce to this problem. The Kan extension is a powerful tool in category theory that generalizes this notion. In this work we explore several applications of Kan extensions to data science. We begin by deriving simple classification and clustering algorithms as Kan extensions and experimenting with these algorithms on real data. Next, we build more complex and resilient algorithms from these simple parts.
Right now Dan works as the Head of Machine Learning at Abnormal Security. Previously. He led the Web Ads Machine Learning team at Twitter. Before that he worked as a Staff ML Engineer at Twitter Cortex and a Senior Data Scientist at TrueMotion.
His PhD research at the University of Oxford focused on applications of Category Theory to Machine Learning (advised by Jeremy Gibbons and Cezar Ionescu). Before that he worked as a Computer Vision Researcher at the Serre Lab.
You can find out more about Dan here: https://danshiebler.com/
Module categories for $\text{Tilt}(SL_{2k+1})$ from $\tilde{A}_{n-1}$-buildings
Abstract
We show that the category of vector bundles over the vertices of a locally finite $\tilde{A}_{n-1}$ building $\Delta$, $Vec(\Delta)$, has the structure of a $Tilt(SL_{2k+1})$ module category. This module category is the $q$-analogue of the $Tilt(SL_{2k+1})$ action on vector bundles over the $sl_n$ weight lattice. Our construction of the $Tilt(SL_{2k+1})$ action on $Vec(\Delta)$ extends to $Vec(\Delta)^{G}$, its equivariantization, which gives us a class of non-standard $Tilt(SL_{2k+1})$ module categories. When $G$ acts simply transitively, this recovers the fiber functors of Jones.
We will be streaming this seminar in L6 but feel free to join online.
The mechanics of alluvial rivers
Abstract
Rivers choose their size and shape, and spontaneously organize into ramified networks. Yet, they are essentially a channelized flow of water that carries sediment. Based on laboratory experiments, field measurements and simple theory, we will investigate the basic mechanisms by which rivers form themselves, and carve the landscapes that surround us.
Systematic elucidation of genetic mechanisms underlying cholesterol uptake
Abstract
The overall goal of the Sherwood lab is to advance genomic and precision medicine applications through high-throughput, multi-disciplinary science. In this talk, I will review a suite of high-throughput genomic and cellular perturbation platforms using CRISPR-based genome editing that the lab has developed to improve our understanding of genetic disease, gene regulation, and genome editing outcomes.
This talk will focus on recent efforts using combined analysis of rare coding variants from the UK Biobank and genome-scale CRISPR-Cas9 knockout and activation screening to improve the identification of genes, coding variants, and non-coding variants whose alteration impacts serum LDL cholesterol (LDL-C) levels. Through these efforts, we show that dysfunction of the RAB10 vesicle transport pathway leads to hypercholesterolemia in humans and mice by impairing surface LDL receptor levels. Further, we demonstrate that loss of function of OTX2 leads to robust reduction in serum LDL-C levels in mice and humans by increasing cellular LDL-C uptake. Finally, we unveil an activity-normalized base editing screening framework to better understand the impacts of coding and non-coding variation on serum LDL-C levels, altogether providing a roadmap for further efforts to dissect complex human disease genetics.
16:00
Understanding the Defect via Ramification Theory
Abstract
Classical ramification theory deals with complete discrete valuation fields k((X)) with perfect residue fields k. Invariants such as the Swan conductor capture important information about extensions of these fields. Many fascinating complications arise when we allow non-discrete valuations and imperfect residue fields k. Particularly in positive residue characteristic, we encounter the mysterious phenomenon of the defect (or ramification deficiency). The occurrence of a non-trivial defect is one of the main obstacles to long-standing problems, such as obtaining resolution of singularities in positive characteristic.
Degree p extensions of valuation fields are building blocks of the general case. In this talk, we will present a generalization of ramification invariants for such extensions and discuss how this leads to a better understanding of the defect. If time permits, we will briefly discuss their connection with some recent work (joint with K. Kato) on upper ramification groups.
An unbounded version of Zarankiewicz's problem
Abstract
Zarankiewicz's problem for hypergraphs asks for upper bounds on the number of edges of a hypergraph that has no complete sub-hypergraphs of a given size. Let M be an o-minimal structure. Basit-Chernikov-Starchenko-Tao-Tran (2021) proved that the following are equivalent:
(1) "linear Zarankiewicz's bounds" hold for hypergraphs whose edge relation is induced by a fixed relation definable in M
(2) M does not define an infinite field.
We prove that the following are equivalent:
(1') linear Zarankiewicz bounds hold for sufficiently "distant" hypergraphs whose edge relation is induced by a fixed relation definable in M
(2') M does not define a full field (that is, one whose domain is the whole universe of M).
This is joint work (in progress) with Aris Papadopoulos.
14:00
A tale of 2-groups: Dp(USp(2N)) theories
Note: we would recommend to join the meeting using the Zoom client for best user experience.
Abstract
After a brief introduction, I elucidate a technique, dubbed "bootstrap'', which generates an infinite family of D_p(G) theories, where for a given arbitrary group G and a parameter b, each theory in the same family has the same number of mass parameters, same number of marginal deformations, same 1-form symmetry, and same 2-group structure. This technique is utilized to establish the presence or absence of the 2-group symmetries in several classes of D_p(G) theories. I, then, argue that we found the presence of 2-group symmetries in a class of Argyres-Douglas theories, called D_p(USp(2N)), which can be realized by Z_2-twisted compactification of the 6d N=(2,0) of the D-type on a sphere with an irregular twisted puncture and a regular twisted full puncture. I will also discuss the 3d mirror theories of general D_p(USp(2N)) theories that serve as an important tool to study their flavor symmetry and Higgs branch.
It is possible to join online via Zoom.
Twenty examples of AAA approximation
Abstract
For the first time, a method has become available for fast computation of near-best rational approximations on arbitrary sets in the real line or complex plane: the AAA algorithm (Nakatsukasa-Sète-T. 2018). After a brief presentation of the algorithm this talk will focus on twenty demonstrations of the kinds of things we can do, all across applied mathematics, with a black-box rational approximation tool.
Analysis and Numerical Approximation of Stationary Second-order Mean Field Game Partial Differential Inclusions
Abstract
The formulation of Mean Field Games (MFG) via partial differential equations typically requires continuous differentiability of the Hamiltonian in order to determine the advective term in the Kolmogorov--Fokker--Planck equation for the density of players. However, in many cases of practical interest, the underlying optimal control problem may exhibit bang-bang controls, which typically lead to nondifferentiable Hamiltonians. In this talk we will present results on the analysis and numerical approximation of stationary second-order MFG systems for the general case of convex, Lipschitz, but possibly nondifferentiable Hamiltonians. In particular, we will propose a generalization of the MFG system as a Partial Differential Inclusion (PDI) based on interpreting the derivative of the Hamiltonian in terms of subdifferentials of convex functions. We present results that guarantee the existence of unique weak solutions to the stationary MFG PDI under a monotonicity condition similar to one that has been considered previously by Lasry and Lions. Moreover, we will propose a monotone finite element discretization of the weak formulation of the MFG PDI, and present results that confirm the strong H^1-norm convergence of the approximations to the value function and strong L^q-norm convergence of the approximations to the density function. The performance of the numerical method will be illustrated in experiments featuring nonsmooth solutions. This talk is based on joint work with my supervisor Iain Smears.
Revisiting Two Classic Surface Tension Problems: Rough Capillary Rise and Fluctuations of Cellular Droplets
Abstract
In this talk I will discuss our recent work on two problems. The first problem concerns with capillary rise between rough structures, a fundamental wetting phenomenon that is functionalised in biological organisms and prevalent in geological or man-made materials. Predicting the liquid rise height is more complex than currently considered in the literature because it is necessary to couple two wetting phenomena: capillary rise and hemiwicking. Experiments, simulations and analytic theory demonstrate how this coupling challenges our conventional understanding and intuitions of wetting and roughness. For example, the critical contact angle for hemiwicking becomes separation-dependent so that hemiwicking can vanish for even highly wetting liquids. The rise heights for perfectly wetting liquids can also be different in smooth and rough systems. The second problem concerns with droplets (or condensates) formed via a liquid-liquid phase separation process in biological cells. Despite the widespread importance of surface tension for the interactions between these droplets and other cellular components, there is currently no reliable technique for their measurement in live cells. To address this, we develop a high-throughput flicker spectroscopy technique. Applying it to a class of cellular droplets known as stress granules, we find their interface fluctuations cannot be described by surface tension alone. It is necessary to consider elastic bending deformation and a non-spherical base shape, suggesting that stress granules are viscoelastic droplets with a structured interface, rather than simple Newtonian liquids. Moreover, given the broad distributions of surface tension and bending rigidity observed, different types of stress granules can only be differentiated via large-scale surveys, which was not possible previously and our technique now enables.
Prof Halim Kusumaatmaja is currently a Professor of Physics at Durham University and he also holds an EPSRC Fellowship in Engineering. Prof Kusumaatmaja graduated with a Master of Physics from the University of Leicester in 2004 and a PhD in Physics from the University of Oxford in 2008. He worked as a Postdoctoral Research Associate at the Max Planck Institute of Colloids and Interfaces (2008-2011) and at the University of Cambridge (2011-2013), before moving to Durham University and rising through the ranks from Assistant Professor (2013-2017) to Associate Professor (2017-2020) and Full Professor (2020-now). Prof Kusumaatmaja leads an interdisciplinary research group in the area of Soft Matter and Biophysics. Current research interests include wetting and interfacial phenomena, bio-inspired materials, liquid-liquid phase separation in biology, multistable elastic structures, colloidal and molecular self-assembly, and high performance computing.
OMI: Artificial Intelligence and Financial Markets workshop - 20th & 21st October 2022
Schedule, titles, abstracts, and bios can be found here.
16:00
$\ell^2$-invariants and generalisations in positive characteristic
Abstract
We survey the theory of $\ell^2$-invariants, their applications in group theory and topology, and introduce a positive characteristic version of $\ell^2$-theory. We also discuss the Atiyah and Lück approximation conjectures, two of the central problems in this area.
16:00
Equivariant Jiang-Su stability
Abstract
Equivariant Jiang-Su stability is an important regularity property for group actions on C*-algebras. In this talk, I will explain this property and how it arises naturally in the context of the classification of C*-algebras and their actions. Depending on the time, I will then explain a bit more about the nature of equivariant Jiang- Su stability and the kind of techniques that are used to study it, including a recent result of Gábor Szabó and myself establishing an equivalence with equivariant property Gamma under certain conditions.