Past

I will discuss algebraic conditions that for a given group guarantee or characterize the vanishing of cohomology in a given degree with coefficients in any unitary representation. These conditions will be expressed in terms positivity of certain elements over group algebras, where positivity is meant as being a sum of hermitian squares. I will explain how conditions like this can be used to give computer-assisted proofs of vanishing of cohomology. 

The Chabauty-Kim method is an effective algorithm for finding the $S$-integral points of hyperbolic curves by directly using the hyperbolicity in group-cohomological arguments. Central objects in the theory are affine spaces known as a Selmer schemes. We'll introduce the CK method and Selmer schemes, and demonstrate some additional structures possessed by Selmer schemes which can aid in implementing the CK method.
 

Two CW-complexes are simple homotopy equivalent if they are related by a sequence of collapses and expansions of cells. It implies homotopy equivalent as is implied by homeomorphic. This notion proved extremely useful in manifold topology and is central to the classification of non-simply connected manifolds up to homeomorphism. I will present the first examples of two 4-manifolds which are homotopy equivalent but not simple homotopy equivalent, as well as in all higher even dimensions. The examples are constructed using surgery theory and the s-cobordism theorem, and are distinguished using methods from algebraic number theory and algebraic K-theory. I will also discuss a number of new directions including progress on classifying the possible fundamental groups for which examples exist. This is joint work with Csaba Nagy and Mark Powell.

In this talk, we present recent results on an anisotropic variant of the Kardar-Parisi-Zhang equation, the Anisotropic KPZ equation (AKPZ), in the critical spatial dimension d=2. This is a singular SPDE which is conjectured to capture the behaviour of the fluctuations of a large family of random surface growth phenomena but whose analysis falls outside of the scope not only of classical stochastic calculus but also of the theory of Regularity Structures and paracontrolled calculus. We first consider a regularised version of the AKPZ equation which preserves the invariant measure and prove the conjecture made in [Cannizzaro, Erhard, Toninelli, "The AKPZ equation at stationarity: logarithmic superdiffusivity"], i.e. we show that, at large scales, the correlation length grows like t1/2 (log t)1/4 up to lower order correction. Second, we prove that in the so-called weak coupling regime, i.e. the equation regularised at scale N and the coefficient of the nonlinearity tuned down by a factor (log N)-1/2, the AKPZ equation converges to a linear stochastic heat equation with renormalised coefficients. Time allowing, we will comment on how some of the techniques introduced can be applied to other SPDEs and physical systems at and above criticality. 

Labourie proved that every Hitchin representation into PSL(n,R) gives rise to an equivariant minimal surface in the corresponding symmetric space. He conjectured that uniqueness holds as well (this was known for n=2,3), and explained that if true, then the Hitchin component admits a mapping class group equivariant parametrization as a holomorphic vector bundle over Teichmüller space.

In this talk, we will define Hitchin representations, Higgs bundles, and minimal surfaces, and give the background for the Labourie conjecture. We will then explain that the conjecture fails for n at least 4, and point to some future questions and conjectures.

To be a mathematicus in 15th- and 16th-century Europe often meant practising as an astrologer. Far from being an unwelcome obligation, or simply a means of paying the rent, astrology frequently represented a genuine form of mathematical engagement. This is most clearly seen by examining changing definitions of one of the key elements of horoscope construction: the astrological houses. These twelve houses are divisions of the zodiac circle and their character fundamentally affects the significance of the planets which occupy them at any particular moment in time. While there were a number of competing systems for defining the houses, one system was standard throughout medieval Europe. However, the 16th-century witnessed what John North referred to as a “minor revolution”, as a different technique first developed in the Islamic world but adopted and promoted by Johannes Regiomontanus became increasingly prevalent. My paper reviews this shift in astrological practice and investigates the mathematical values it represents – from aesthetics and geometrical representation to efficiency and computational convenience.

Quantum field theories (QFTs) in d dimensions that posses a (d-1)-form symmetry are conjectured to decompose into disjoint “universes”, each of which is itself a (local and unitary) QFT. I will give an overview of our current understanding of decomposition, and then discuss how this phenomenon occurs in the fusion of condensation defects of certain 3d QFTs. This gives a “microscopic” explanation of why in these instances, the fusion coefficient can be taken as an integer rather than a general TQFT.

Academic research can be challenging and can bring with it difficulties in maintaining good mental health. This session will be led by Rebecca Reed, Mental Health First Aid (MHFA) Instructor, Meditation & Yoga Teacher and Personal Development Coach and owner of wellbeing company Siendo. Rebecca will talk about how we can maintain good mental fitness, recognizing good practices to ensure we avoid mental-health difficulties before they begin. We have deliberately set this session to be at the beginning of the academic year in this spirit. We will also talk about maintaining good mental health specifically in the academic community.   

 I will start this talk with a brief introduction and summary of the outcome of a joint work with James Gabe. An important special case of the main result is that for any countable discrete amenable group G, any two outer G-actions on stable Kirchberg algebras are cocycle conjugate precisely when they are equivariantly KK-equivalent. In the main body of the talk, I will outline the key arguments toward a special case of the 'uniqueness theorem', which is one of the fundamental ingredients in our theory: Suppose we have two G-actions on A and B such that B is a stable Kirchberg algebra and the action on B is outer and equivariantly O_2-absorbing. Then any two cocycle embeddings from A to B are approximately unitarily equivalent. If time permits, I will provide a (very rough) sketch of how this leads to the dynamical O_2-embedding theorem, which implies that such cocycle embeddings always exist in the first place.

A common problem in data science is "use this function defined over this small set to generate predictions over that larger set." Extrapolation, interpolation, statistical inference and forecasting all reduce to this problem. The Kan extension is a powerful tool in category theory that generalizes this notion. In this work we explore several applications of Kan extensions to data science. We begin by deriving simple classification and clustering algorithms as Kan extensions and experimenting with these algorithms on real data. Next, we build more complex and resilient algorithms from these simple parts.

We show that the category of vector bundles over the vertices of a locally finite $\tilde{A}_{n-1}$ building $\Delta$, $Vec(\Delta)$, has the structure of a $Tilt(SL_{2k+1})$ module category. This module category is the $q$-analogue of the $Tilt(SL_{2k+1})$ action on vector bundles over the $sl_n$ weight lattice.  Our construction of the $Tilt(SL_{2k+1})$ action on $Vec(\Delta)$ extends to $Vec(\Delta)^{G}$, its equivariantization, which gives us a class of non-standard $Tilt(SL_{2k+1})$ module categories. When $G$ acts simply transitively, this recovers the fiber functors of Jones.

Rivers choose their size and shape, and spontaneously organize into ramified networks. Yet, they are essentially a channelized flow of water that carries sediment. Based on laboratory experiments, field measurements and simple theory, we will investigate the basic mechanisms by which rivers form themselves, and carve the landscapes that surround us.

The overall goal of the Sherwood lab is to advance genomic and precision medicine applications through high-throughput, multi-disciplinary science. In this talk, I will review a suite of high-throughput genomic and cellular perturbation platforms using CRISPR-based genome editing that the lab has developed to improve our understanding of genetic disease, gene regulation, and genome editing outcomes.

This talk will focus on recent efforts using combined analysis of rare coding variants from the UK Biobank and genome-scale CRISPR-Cas9 knockout and activation screening to improve the identification of genes, coding variants, and non-coding variants whose alteration impacts serum LDL cholesterol (LDL-C) levels. Through these efforts, we show that dysfunction of the RAB10 vesicle transport pathway leads to hypercholesterolemia in humans and mice by impairing surface LDL receptor levels. Further, we demonstrate that loss of function of OTX2 leads to robust reduction in serum LDL-C levels in mice and humans by increasing cellular LDL-C uptake. Finally, we unveil an activity-normalized base editing screening framework to better understand the impacts of coding and non-coding variation on serum LDL-C levels, altogether providing a roadmap for further efforts to dissect complex human disease genetics.

Classical ramification theory deals with complete discrete valuation fields k((X)) with perfect residue fields k. Invariants such as the Swan conductor capture important information about extensions of these fields. Many fascinating complications arise when we allow non-discrete valuations and imperfect residue fields k. Particularly in positive residue characteristic, we encounter the mysterious phenomenon of the defect (or ramification deficiency). The occurrence of a non-trivial defect is one of the main obstacles to long-standing problems, such as obtaining resolution of singularities in positive characteristic.

Degree p extensions of valuation fields are building blocks of the general case. In this talk, we will present a generalization of ramification invariants for such extensions and discuss how this leads to a better understanding of the defect. If time permits, we will briefly discuss their connection with some recent work (joint with K. Kato) on upper ramification groups.

Zarankiewicz's problem for hypergraphs asks for upper bounds on the number of edges of a hypergraph that has no complete sub-hypergraphs of a given size. Let M be an o-minimal structure. Basit-Chernikov-Starchenko-Tao-Tran (2021) proved that the following are equivalent:

(1) "linear Zarankiewicz's bounds" hold for hypergraphs whose edge relation is induced by a fixed relation definable in M

(2) M does not define an infinite field.

We prove that the following are equivalent:

(1') linear Zarankiewicz bounds hold for sufficiently "distant" hypergraphs whose edge relation is induced by a fixed relation definable in M

(2') M does not define a full field (that is, one whose domain is the whole universe of M).

This is joint work (in progress) with Aris Papadopoulos.

After a brief introduction, I elucidate a technique, dubbed "bootstrap'', which generates an infinite family of D_p(G) theories, where for a given arbitrary group G and a parameter b, each theory in the same family has the same number of mass parameters, same number of marginal deformations, same 1-form symmetry, and same 2-group structure. This technique is utilized to establish the presence or absence of the 2-group symmetries in several classes of D_p(G) theories. I, then, argue that we found the presence of 2-group symmetries in a class of Argyres-Douglas theories, called D_p(USp(2N)), which can be realized by Z_2-twisted compactification of the 6d N=(2,0) of the D-type on a sphere with an irregular twisted puncture and a regular twisted full puncture. I will also discuss the 3d mirror theories of general D_p(USp(2N)) theories that serve as an important tool to study their flavor symmetry and Higgs branch.

For the first time, a method has become available for fast computation of near-best rational approximations on arbitrary sets in the real line or complex plane: the AAA algorithm (Nakatsukasa-Sète-T. 2018).  After a brief presentation of the algorithm this talk will focus on twenty demonstrations of the kinds of things we can do, all across applied mathematics, with a black-box rational approximation tool.
 

The formulation of Mean Field Games (MFG) via partial differential equations typically requires continuous differentiability of the Hamiltonian in order to determine the advective term in the Kolmogorov--Fokker--Planck equation for the density of players. However, in many cases of practical interest, the underlying optimal control problem may exhibit bang-bang controls, which typically lead to nondifferentiable Hamiltonians. In this talk we will present results on the analysis and numerical approximation of stationary second-order MFG systems for the general case of convex, Lipschitz, but possibly nondifferentiable Hamiltonians. In particular, we will propose a generalization of the MFG system as a Partial Differential Inclusion (PDI) based on interpreting the derivative of the Hamiltonian in terms of subdifferentials of convex functions. We present results that guarantee the existence of unique weak solutions to the stationary MFG PDI under a monotonicity condition similar to one that has been considered previously by Lasry and Lions. Moreover, we will propose a monotone finite element discretization of the weak formulation of the MFG PDI, and present results that confirm the strong H^1-norm convergence of the approximations to the value function and strong L^q-norm convergence of the approximations to the density function. The performance of the numerical method will be illustrated in experiments featuring nonsmooth solutions. This talk is based on joint work with my supervisor Iain Smears.

In this talk I will discuss our recent work on two problems. The first problem concerns with capillary rise between rough structures, a fundamental wetting phenomenon that is functionalised in biological organisms and prevalent in geological or man-made materials. Predicting the liquid rise height is more complex than currently considered in the literature because it is necessary to couple two wetting phenomena: capillary rise and hemiwicking. Experiments, simulations and analytic theory demonstrate how this coupling challenges our conventional understanding and intuitions of wetting and roughness. For example, the critical contact angle for hemiwicking becomes separation-dependent so that hemiwicking can vanish for even highly wetting liquids. The rise heights for perfectly wetting liquids can also be different in smooth and rough systems. The second problem concerns with droplets (or condensates) formed via a liquid-liquid phase separation process in biological cells. Despite the widespread importance of surface tension for the interactions between these droplets and other cellular components, there is currently no reliable technique for their measurement in live cells. To address this, we develop a high-throughput flicker spectroscopy technique. Applying it to a class of cellular droplets known as stress granules, we find their interface fluctuations cannot be described by surface tension alone. It is necessary to consider elastic bending deformation and a non-spherical base shape, suggesting that stress granules are viscoelastic droplets with a structured interface, rather than simple Newtonian liquids. Moreover, given the broad distributions of surface tension and bending rigidity observed, different types of stress granules can only be differentiated via large-scale surveys, which was not possible previously and our technique now enables.

We survey the theory of $\ell^2$-invariants, their applications in group theory and topology, and introduce a positive characteristic version of $\ell^2$-theory. We also discuss the Atiyah and Lück approximation conjectures, two of the central problems in this area.