Thu, 16 Mar 2017

12:00 - 13:00
L5

"Analytic geometry over the field with one element"

Yakov Kremnitzer
(Oxford)
Abstract

1.Kremnitzer. I will explain an approach to constructing geometries relative to a symmetric monoidal 
category. I will then introduce the category of normed sets as a possible analytic geometry over 
the field with one element. I will show that the Fargues-Fontaine curve from p-adic Hodge theory and 
the Connes-Bost system are naturally interpreted in this geometry. This is joint work with Federico Bambozzi and 
Oren Ben-Bassat.
 

Thu, 04 May 2017
16:00
L6

Joint Number Theory/Logic Seminar: On the Hilbert Property and the fundamental group of algebraic varieties

Umberto Zannier
(Scuola Normale Superiore di Pisa)
Abstract

This  concerns recent work with P. Corvaja in which we relate the Hilbert Property for an algebraic variety (a kind of axiom linked with Hilbert Irreducibility, relevant e.g. for the Inverse Galois Problem)  with the fundamental group of the variety.
 In particular, this leads to new examples (of surfaces) of  failure of the Hilbert Property. We also prove the Hilbert Property for a non-rational surface (whereas all previous examples involved rational varieties).

Thu, 25 May 2017
16:00
L6

Reduction of dynatomic curves

Holly Krieger
(Cambridge)
Abstract

Dynatomic curves parametrize n-periodic orbits of a one-parameter family of polynomial dynamical systems. These curves lack the structure of their arithmetic-geometric analogues (modular curves of level n) but can be studied dynamically.  Morton and Silverman conjectured a dynamical analogue of the uniform boundedness conjecture (theorems of Mazur, Merel), asserting uniform bounds for the number of rational periodic points for such a family.  I will discuss recent work towards the function field version of their conjecture, including results on the reduction mod p of dynatomic curves for the quadratic polynomial family z^2+c.

Oxford Mathematician Neave O’Clery recently moved to Oxford from the Center for International Development at Harvard University where she worked on the development of mathematical models to describe the processes behind industrial diversification and economic growth. Here she discusses how network science can help us understand the success of cities, and provide practical tools for policy-makers. 

Fri, 09 Jun 2017

14:00 - 15:00
L3

From estimating motion to monitoring complex behaviour in cellular systems

Professor Jens Rittscher
(Dept of Engineering Science University of Oxford)
Abstract

Building on advancements in computer vision we now have an array of visual tracking methods that allow the reliable estimation of cellular motion in high-throughput settings as well as more complex biological specimens. In many cases the underlying assumptions of these methods are still not well defined and result in failures when analysing large scale experiments.

Using organotypic co-culture systems we can now mimic more physiologically relevant microenvironments in vitro.  The robust analysis of cellular dynamics in such complex biological systems remains an open challenge. I will attempt to outline some of these challenges and provide some very preliminary results on analysing more complex cellular behaviours.

Fri, 02 Jun 2017

14:00 - 15:00
L3

Cell cycle regulation by systems-level feedback control

Prof Bela Novak
(Dept of Biochemistry University of Oxford)
Abstract

In the first part of my presentation, I will briefly summarize a dynamic view of the cell cycle created in collaboration with Prof John Tyson over the past 25 years. 
In our view, the decisions a cell must make during DNA synthesis and mitosis are controlled by bistable switches, which provide abrupt and irreversible transition 
between successive cell cycle phases. In addition, bistability provides the foundation for 'checkpoints' that can stop cell proliferation if problems arise 
(e.g., DNA damage by UV irradiation). In the second part of my talk, I will highlight a few representative examples from our ongoing BBSRC Strategic LoLa grant 
(http://cellcycle.org.uk/) in which we are testing the predictions of our theoretical ideas in human cells in collaboration with four experimental groups.

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