Professor Colin Please works on the mathematical modelling of physical phenomena arising in practical problems and interpreting the results
into the original context His research takes place at the interface ofmathematics with other disciplines primarily engineering, and bio-science. He develops mathematical models primarily using partial differential equations employing asymptotic methods and numerical methods to understand the resulting behaviour.  He has a particular longstanding interest in Mathematics with Industry Study Groups which are very active in the UK with rapidly growing similar activities internationally.  These Study Groups bring academic mathematicians together with practitioners in
industry to identify methods for modelling their technical problems arising in industrial manufacturing processes. They are a fantastic method for training new applied mathematicians in the methods of mathematical modelling.

He is a director of the EPSRC Centre for Doctoral Training in Industrially Focussed Mathematical Modelling.