+44 1865 283876
University of Oxford
Andrew Wiles Building
Radcliffe Observatory Quarter
The influence of receptor-mediated interactions on reaction-diffusion mechanisms of cellular self-organisation.
Bull Math Biol issue 4 volume 74 page 935-957 (April 2012) Full text available
Nonlinear instability in flagellar dynamics: a novel modulation mechanism in sperm migration?
J R Soc Interface issue 53 volume 7 page 1689-1697 (6 December 2010) Full text available
Modelling bacterial behaviour close to a no-slip plane boundary: The influence of bacterial geometry
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences issue 2118 volume 466 page 1725-1748 (8 June 2010)
Human sperm accumulation near surfaces: A simulation study
Journal of Fluid Mechanics volume 621 page 289-320 (26 May 2009)
A mass action model of a Fibroblast Growth Factor signaling pathway and its simplification.
Bull Math Biol issue 8 volume 70 page 2229-2263 (November 2008) Full text available
Human sperm swimming in a high viscosity mucus analogue.
Journal of theoretical biology volume 446 page 1-10 (June 2018)
Theoretical Insights Into the Retinal Dynamics of VEGF in Patients Treated with Ranibizumab, Based on an Ocular Pharmacokinetic/Pharmacodynamic Model.
Mol Pharm (7 May 2018) Full text available
Changes in the retreatment radiation tolerance of the spinal cord with time after the initial treatment.
International journal of radiation biology page 1-17 (5 April 2018)
Predictive Mathematical Models for the Spread and Treatment of Hyperoxia-induced Photoreceptor Degeneration in Retinitis Pigmentosa.
Investigative ophthalmology & visual science issue 3 volume 59 page 1238-1249 (March 2018)
An in silico model of cytotoxic T-lymphocyte activation in the lymph node following short peptide vaccination
JOURNAL OF THE ROYAL SOCIETY INTERFACE issue 140 volume 15 (March 2018) Full text available
My research objectives are typically to extract the macroscale consequences of mechanisms operating at much smaller scales, usually the microbiological level, for instance how cells interact and signal, together with the associated biophysics of reaction, diffusion, deformation and flow. This requires detailed mathematical modelling, combined with mathematical analyses, asymptotics, computation and model interpretation within numerous application areas of the life and biomedical sciences. The application areas include cell motility, especially flagellated cell swimming, bacterial dynamics, ecological invasions and mechanisms of biological self-organisation together with the modelling of select processes in physiological transport and solid tumour development.