Personal Website:
+44 1865 283876
Address
University of Oxford
Andrew Wiles Building
Radcliffe Observatory Quarter
Woodstock Road
Oxford
OX2 6GG
Highlighted Publications:
The influence of receptor-mediated interactions on reaction-diffusion mechanisms of cellular self-organisation.
Bull Math Biol
issue 4
volume 74
page 935-957
(April 2012)
Full text available
Nonlinear instability in flagellar dynamics: a novel modulation mechanism in sperm migration?
J R Soc Interface
issue 53
volume 7
page 1689-1697
(6 December 2010)
Full text available
Modelling bacterial behaviour close to a no-slip plane boundary: The influence of bacterial geometry
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences
issue 2118
volume 466
page 1725-1748
(8 June 2010)
Human sperm accumulation near surfaces: A simulation study
Journal of Fluid Mechanics
volume 621
page 289-320
(26 May 2009)
A mass action model of a Fibroblast Growth Factor signaling pathway and its simplification.
Bull Math Biol
issue 8
volume 70
page 2229-2263
(November 2008)
Full text available
Recent Publications:
Osmotic and electroosmotic fluid transport across the retinal pigment epithelium: A mathematical model.
Journal of theoretical biology
volume 456
page 233-248
(November 2018)
Hydrodynamic Clustering of Human Sperm in Viscoelastic Fluids.
Scientific reports
issue 1
volume 8
page 15600-
(22 October 2018)
Domain Size Driven Instability: Self-organisation in Systems with Advection
SIAM Journal on Applied Mathematics
(4 September 2018)
Applications of mechanistic modelling to clinical and experimental immunology: an emerging technology to accelerate immunotherapeutic discovery and development.
Clinical and experimental immunology
issue 3
volume 193
page 284-292
(September 2018)
An elastohydrodynamical simulation study of filament and spermatozoan swimming driven by internal couples
IMA Journal of Applied Mathematics (Institute of Mathematics and Its Applications)
issue 4
volume 83
page 655-679
(25 July 2018)
Research Interests:
My research objectives are typically to extract the macroscale consequences of mechanisms operating at much smaller scales, usually the microbiological level, for instance how cells interact and signal, together with the associated biophysics of reaction, diffusion, deformation and flow. This requires detailed mathematical modelling, combined with mathematical analyses, asymptotics, computation and model interpretation within numerous application areas of the life and biomedical sciences. The application areas include cell motility, especially flagellated cell swimming, bacterial dynamics, ecological invasions and mechanisms of biological self-organisation together with the modelling of select processes in physiological transport and solid tumour development.