Personal Website:
+44 1865 283876
Address
University of Oxford
Andrew Wiles Building
Radcliffe Observatory Quarter
Woodstock Road
Oxford
OX2 6GG
Highlighted Publications:
The influence of receptor-mediated interactions on reaction-diffusion mechanisms of cellular self-organisation.
Bull Math Biol
issue 4
volume 74
page 935-957
(April 2012)
Full text available
Nonlinear instability in flagellar dynamics: a novel modulation mechanism in sperm migration?
J R Soc Interface
issue 53
volume 7
page 1689-1697
(6 December 2010)
Full text available
Modelling bacterial behaviour close to a no-slip plane boundary: The influence of bacterial geometry
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences
issue 2118
volume 466
page 1725-1748
(8 June 2010)
Human sperm accumulation near surfaces: A simulation study
Journal of Fluid Mechanics
volume 621
page 289-320
(26 May 2009)
A mass action model of a Fibroblast Growth Factor signaling pathway and its simplification.
Bull Math Biol
issue 8
volume 70
page 2229-2263
(November 2008)
Full text available
Recent Publications:
Theoretical Insights into the Retinal Dynamics of Vascular Endothelial Growth Factor in Patients Treated with Ranibizumab, Based on an Ocular Pharmacokinetic/Pharmacodynamic Model.
Molecular pharmaceutics
issue 7
volume 15
page 2770-2784
(July 2018)
Changes in the retreatment radiation tolerance of the spinal cord with time after the initial treatment.
International journal of radiation biology
issue 6
volume 94
page 515-531
(June 2018)
Human sperm swimming in a high viscosity mucus analogue.
Journal of theoretical biology
volume 446
page 1-10
(June 2018)
The mechanics of phantom Mikado networks
Journal of Physics Communications
(14 May 2018)
Basal Tear Osmolarity as a metric to estimate body hydration and dry eye severity.
Progress in retinal and eye research
volume 64
page 56-64
(May 2018)
Research Interests:
My research objectives are typically to extract the macroscale consequences of mechanisms operating at much smaller scales, usually the microbiological level, for instance how cells interact and signal, together with the associated biophysics of reaction, diffusion, deformation and flow. This requires detailed mathematical modelling, combined with mathematical analyses, asymptotics, computation and model interpretation within numerous application areas of the life and biomedical sciences. The application areas include cell motility, especially flagellated cell swimming, bacterial dynamics, ecological invasions and mechanisms of biological self-organisation together with the modelling of select processes in physiological transport and solid tumour development.