Prof. Eamonn Gaffney | Mathematical Institute

Prof. Eamonn Gaffney

Status:

Academic Faculty

Contact form

Personal website:

http://people.maths.ox.ac.uk/gaffney/

+44 1865 283876

ORCID iD:

https://orcid.org/0000-0002-6888-4362

Research groups:

Mathematical Biology

Address

Mathematical Institute
University of Oxford
Andrew Wiles Building
Radcliffe Observatory Quarter
Woodstock Road
Oxford
OX2 6GG

Highlighted Publications:

The influence of receptor-mediated interactions on reaction-diffusion mechanisms of cellular self-organisation.

The influence of receptor-mediated interactions on reaction-diffusion mechanisms of cellular self-organisation.
Klika, V; Baker, R; Headon, D; Gaffney, E
Bull Math Biol issue 4 volume 74 page 935-957 (April 2012) Full text available

Nonlinear instability in flagellar dynamics: a novel modulation mechanism in sperm migration?

Nonlinear instability in flagellar dynamics: a novel modulation mechanism in sperm migration?
Gadêlha, H; Gaffney, E; Smith, D; Kirkman-Brown, J
J R Soc Interface issue 53 volume 7 page 1689-1697 (6 December 2010) Full text available

Modelling bacterial behaviour close to a no-slip plane boundary: The influence of bacterial geometry

Modelling bacterial behaviour close to a no-slip plane boundary: The influence of bacterial geometry
Shum, H; Gaffney, E; Smith, D
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences issue 2118 volume 466 page 1725-1748 (8 June 2010)

Human sperm accumulation near surfaces: A simulation study

Human sperm accumulation near surfaces: A simulation study
Smith, D; Gaffney, E; Blake, J; Kirkman-Brown, J
Journal of Fluid Mechanics volume 621 page 289-320 (26 May 2009)

A mass action model of a Fibroblast Growth Factor signaling pathway and its simplification.

A mass action model of a Fibroblast Growth Factor signaling pathway and its simplification.
Gaffney, E; Heath, J; Kwiatkowska, M
Bull Math Biol issue 8 volume 70 page 2229-2263 (November 2008) Full text available

Recent Publications:

The combined impact of tissue heterogeneity and fixed charge for models of cartilage: the one-dimensional biphasic swelling model revisited.

The combined impact of tissue heterogeneity and fixed charge for models of cartilage: the one-dimensional biphasic swelling model revisited.
Klika, V; Whiteley, J; Brown, C; Gaffney, E
Biomechanics and modeling in mechanobiology issue 4 volume 18 page 953-968 (August 2019)

Systems-level analysis of monocyte responses in inflammatory bowel disease identifies IL-10 and IL-1 cytokine networks that regulate IL-23

Systems-level analysis of monocyte responses in inflammatory bowel disease identifies IL-10 and IL-1 cytokine networks that regulate IL-23
ASCHENBRENNER, D; Quaranta, M; BANERJEE, S; ILOTT, N; Jansen, J; Steere, B; Chen, Y; Ho, S; Cox, K; ARANCIBIA, C; COLES, M; GAFFNEY, E; Travis, S; Denson, L; Kugathasan, S; Schmitz, J; POWRIE, F; SANSOM, S; UHLIG, H
(31 July 2019)

Flagellar ultrastructure suppresses buckling instabilities and enables mammalian sperm navigation in high-viscosity media.

Flagellar ultrastructure suppresses buckling instabilities and enables mammalian sperm navigation in high-viscosity media.
Gadêlha, H; Gaffney, E
Journal of the Royal Society Interface issue 152 volume 16 page 20180668- (March 2019)

Integrated method for quantitative morphometry and oxygen transport modeling in striated muscle.

Integrated method for quantitative morphometry and oxygen transport modeling in striated muscle.
Al-Shammari, A; Kissane, R; Holbek, S; Mackey, A; Andersen, T; Gaffney, E; Kjaer, M; Egginton, S
Journal of applied physiology (Bethesda, Md. : 1985) issue 3 volume 126 page 544-557 (March 2019)

Feather arrays are patterned by interacting signalling and cell density waves.

Feather arrays are patterned by interacting signalling and cell density waves.
Ho, W; Freem, L; Zhao, D; Painter, K; Woolley, T; Gaffney, E; McGrew, M; Tzika, A; Milinkovitch, M; Schneider, P; Drusko, A; Matthäus, F; Glover, J; Wells, K; Johansson, J; Davey, M; Sang, H; Clinton, M; Headon, D
PLoS biology issue 2 volume 17 page e3000132- (21 February 2019)

gaffney@maths.ox.ac.uk

Research interests:

My research objectives are typically to extract the macroscale consequences of mechanisms operating at much smaller scales, usually the microbiological level, for instance how cells interact and signal, together with the associated biophysics of reaction, diffusion, deformation and flow. This requires detailed mathematical modelling, combined with mathematical analyses, asymptotics, computation and model interpretation within numerous application areas of the life and biomedical sciences. The application areas include cell motility, especially flagellated cell swimming, bacterial dynamics, ecological invasions and mechanisms of biological self-organisation together with the modelling of select processes in physiological transport and solid tumour development.

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