Eleonora Agostinelli

My research focuses on combining structured population models, asymptotic techniques and a multiphase framework to understand the dynamics of macrophages and their interactions with extracellular material in early atherosclerotic plaque. I am currently working on discrete-to-continuum approximations of structured mathematical models using asymptotic methods. I use boundary layer analysis to understand various asymptotic regions of the state space that appear degenerate. My focus is particularly on models that include cell proliferation, and I am interested in investigating how and under what conditions different proliferation distributions upscale to the same leading order continuum model.