16:00
Recasting Selmer Schemes
Abstract
The Chabauty-Kim method is an effective algorithm for finding the $S$-integral points of hyperbolic curves by directly using the hyperbolicity in group-cohomological arguments. Central objects in the theory are affine spaces known as a Selmer schemes. We'll introduce the CK method and Selmer schemes, and demonstrate some additional structures possessed by Selmer schemes which can aid in implementing the CK method.
15:30
Simple homotopy types of 4-manifolds
Abstract
Two CW-complexes are simple homotopy equivalent if they are related by a sequence of collapses and expansions of cells. It implies homotopy equivalent as is implied by homeomorphic. This notion proved extremely useful in manifold topology and is central to the classification of non-simply connected manifolds up to homeomorphism. I will present the first examples of two 4-manifolds which are homotopy equivalent but not simple homotopy equivalent, as well as in all higher even dimensions. The examples are constructed using surgery theory and the s-cobordism theorem, and are distinguished using methods from algebraic number theory and algebraic K-theory. I will also discuss a number of new directions including progress on classifying the possible fundamental groups for which examples exist. This is joint work with Csaba Nagy and Mark Powell.
Edwards-Wilkinson fluctuations for the Anisotropic KPZ in the weak coupling regime
Abstract
In this talk, we present recent results on an anisotropic variant of the Kardar-Parisi-Zhang equation, the Anisotropic KPZ equation (AKPZ), in the critical spatial dimension d=2. This is a singular SPDE which is conjectured to capture the behaviour of the fluctuations of a large family of random surface growth phenomena but whose analysis falls outside of the scope not only of classical stochastic calculus but also of the theory of Regularity Structures and paracontrolled calculus. We first consider a regularised version of the AKPZ equation which preserves the invariant measure and prove the conjecture made in [Cannizzaro, Erhard, Toninelli, "The AKPZ equation at stationarity: logarithmic superdiffusivity"], i.e. we show that, at large scales, the correlation length grows like t1/2 (log t)1/4 up to lower order correction. Second, we prove that in the so-called weak coupling regime, i.e. the equation regularised at scale N and the coefficient of the nonlinearity tuned down by a factor (log N)-1/2, the AKPZ equation converges to a linear stochastic heat equation with renormalised coefficients. Time allowing, we will comment on how some of the techniques introduced can be applied to other SPDEs and physical systems at and above criticality.
14:15
Hitchin representations and minimal surfaces in symmetric spaces
Abstract
Labourie proved that every Hitchin representation into PSL(n,R) gives rise to an equivariant minimal surface in the corresponding symmetric space. He conjectured that uniqueness holds as well (this was known for n=2,3), and explained that if true, then the Hitchin component admits a mapping class group equivariant parametrization as a holomorphic vector bundle over Teichmüller space.
In this talk, we will define Hitchin representations, Higgs bundles, and minimal surfaces, and give the background for the Labourie conjecture. We will then explain that the conjecture fails for n at least 4, and point to some future questions and conjectures.
Going All Round the Houses: Mathematics, Horoscopes and History before 1600
Abstract
To be a mathematicus in 15th- and 16th-century Europe often meant practising as an astrologer. Far from being an unwelcome obligation, or simply a means of paying the rent, astrology frequently represented a genuine form of mathematical engagement. This is most clearly seen by examining changing definitions of one of the key elements of horoscope construction: the astrological houses. These twelve houses are divisions of the zodiac circle and their character fundamentally affects the significance of the planets which occupy them at any particular moment in time. While there were a number of competing systems for defining the houses, one system was standard throughout medieval Europe. However, the 16th-century witnessed what John North referred to as a “minor revolution”, as a different technique first developed in the Islamic world but adopted and promoted by Johannes Regiomontanus became increasingly prevalent. My paper reviews this shift in astrological practice and investigates the mathematical values it represents – from aesthetics and geometrical representation to efficiency and computational convenience.
13:00
Decomposition and condensation defects in 3d
Abstract
Quantum field theories (QFTs) in d dimensions that posses a (d-1)-form symmetry are conjectured to decompose into disjoint “universes”, each of which is itself a (local and unitary) QFT. I will give an overview of our current understanding of decomposition, and then discuss how this phenomenon occurs in the fusion of condensation defects of certain 3d QFTs. This gives a “microscopic” explanation of why in these instances, the fusion coefficient can be taken as an integer rather than a general TQFT.
Maintaining your mental fitness as a graduate student or postdoc
Abstract
Academic research can be challenging and can bring with it difficulties in maintaining good mental health. This session will be led by Rebecca Reed, Mental Health First Aid (MHFA) Instructor, Meditation & Yoga Teacher and Personal Development Coach and owner of wellbeing company Siendo. Rebecca will talk about how we can maintain good mental fitness, recognizing good practices to ensure we avoid mental-health difficulties before they begin. We have deliberately set this session to be at the beginning of the academic year in this spirit. We will also talk about maintaining good mental health specifically in the academic community.
16:00
Selected aspects of the dynamical Kirchberg-Phillips theorem
Abstract
I will start this talk with a brief introduction and summary of the outcome of a joint work with James Gabe. An important special case of the main result is that for any countable discrete amenable group G, any two outer G-actions on stable Kirchberg algebras are cocycle conjugate precisely when they are equivariantly KK-equivalent. In the main body of the talk, I will outline the key arguments toward a special case of the 'uniqueness theorem', which is one of the fundamental ingredients in our theory: Suppose we have two G-actions on A and B such that B is a stable Kirchberg algebra and the action on B is outer and equivariantly O_2-absorbing. Then any two cocycle embeddings from A to B are approximately unitarily equivalent. If time permits, I will provide a (very rough) sketch of how this leads to the dynamical O_2-embedding theorem, which implies that such cocycle embeddings always exist in the first place.
Kan Extensions and Kan Ensembles in Machine Learning
Abstract
A common problem in data science is "use this function defined over this small set to generate predictions over that larger set." Extrapolation, interpolation, statistical inference and forecasting all reduce to this problem. The Kan extension is a powerful tool in category theory that generalizes this notion. In this work we explore several applications of Kan extensions to data science. We begin by deriving simple classification and clustering algorithms as Kan extensions and experimenting with these algorithms on real data. Next, we build more complex and resilient algorithms from these simple parts.
Right now Dan works as the Head of Machine Learning at Abnormal Security. Previously. He led the Web Ads Machine Learning team at Twitter. Before that he worked as a Staff ML Engineer at Twitter Cortex and a Senior Data Scientist at TrueMotion.
His PhD research at the University of Oxford focused on applications of Category Theory to Machine Learning (advised by Jeremy Gibbons and Cezar Ionescu). Before that he worked as a Computer Vision Researcher at the Serre Lab.
You can find out more about Dan here: https://danshiebler.com/
Module categories for $\text{Tilt}(SL_{2k+1})$ from $\tilde{A}_{n-1}$-buildings
Abstract
We show that the category of vector bundles over the vertices of a locally finite $\tilde{A}_{n-1}$ building $\Delta$, $Vec(\Delta)$, has the structure of a $Tilt(SL_{2k+1})$ module category. This module category is the $q$-analogue of the $Tilt(SL_{2k+1})$ action on vector bundles over the $sl_n$ weight lattice. Our construction of the $Tilt(SL_{2k+1})$ action on $Vec(\Delta)$ extends to $Vec(\Delta)^{G}$, its equivariantization, which gives us a class of non-standard $Tilt(SL_{2k+1})$ module categories. When $G$ acts simply transitively, this recovers the fiber functors of Jones.
We will be streaming this seminar in L6 but feel free to join online.
The mechanics of alluvial rivers
Abstract
Rivers choose their size and shape, and spontaneously organize into ramified networks. Yet, they are essentially a channelized flow of water that carries sediment. Based on laboratory experiments, field measurements and simple theory, we will investigate the basic mechanisms by which rivers form themselves, and carve the landscapes that surround us.
Systematic elucidation of genetic mechanisms underlying cholesterol uptake
Abstract
The overall goal of the Sherwood lab is to advance genomic and precision medicine applications through high-throughput, multi-disciplinary science. In this talk, I will review a suite of high-throughput genomic and cellular perturbation platforms using CRISPR-based genome editing that the lab has developed to improve our understanding of genetic disease, gene regulation, and genome editing outcomes.
This talk will focus on recent efforts using combined analysis of rare coding variants from the UK Biobank and genome-scale CRISPR-Cas9 knockout and activation screening to improve the identification of genes, coding variants, and non-coding variants whose alteration impacts serum LDL cholesterol (LDL-C) levels. Through these efforts, we show that dysfunction of the RAB10 vesicle transport pathway leads to hypercholesterolemia in humans and mice by impairing surface LDL receptor levels. Further, we demonstrate that loss of function of OTX2 leads to robust reduction in serum LDL-C levels in mice and humans by increasing cellular LDL-C uptake. Finally, we unveil an activity-normalized base editing screening framework to better understand the impacts of coding and non-coding variation on serum LDL-C levels, altogether providing a roadmap for further efforts to dissect complex human disease genetics.
16:00
Understanding the Defect via Ramification Theory
Abstract
Classical ramification theory deals with complete discrete valuation fields k((X)) with perfect residue fields k. Invariants such as the Swan conductor capture important information about extensions of these fields. Many fascinating complications arise when we allow non-discrete valuations and imperfect residue fields k. Particularly in positive residue characteristic, we encounter the mysterious phenomenon of the defect (or ramification deficiency). The occurrence of a non-trivial defect is one of the main obstacles to long-standing problems, such as obtaining resolution of singularities in positive characteristic.
Degree p extensions of valuation fields are building blocks of the general case. In this talk, we will present a generalization of ramification invariants for such extensions and discuss how this leads to a better understanding of the defect. If time permits, we will briefly discuss their connection with some recent work (joint with K. Kato) on upper ramification groups.
An unbounded version of Zarankiewicz's problem
Abstract
Zarankiewicz's problem for hypergraphs asks for upper bounds on the number of edges of a hypergraph that has no complete sub-hypergraphs of a given size. Let M be an o-minimal structure. Basit-Chernikov-Starchenko-Tao-Tran (2021) proved that the following are equivalent:
(1) "linear Zarankiewicz's bounds" hold for hypergraphs whose edge relation is induced by a fixed relation definable in M
(2) M does not define an infinite field.
We prove that the following are equivalent:
(1') linear Zarankiewicz bounds hold for sufficiently "distant" hypergraphs whose edge relation is induced by a fixed relation definable in M
(2') M does not define a full field (that is, one whose domain is the whole universe of M).
This is joint work (in progress) with Aris Papadopoulos.
14:00
A tale of 2-groups: Dp(USp(2N)) theories
Note: we would recommend to join the meeting using the Zoom client for best user experience.
Abstract
After a brief introduction, I elucidate a technique, dubbed "bootstrap'', which generates an infinite family of D_p(G) theories, where for a given arbitrary group G and a parameter b, each theory in the same family has the same number of mass parameters, same number of marginal deformations, same 1-form symmetry, and same 2-group structure. This technique is utilized to establish the presence or absence of the 2-group symmetries in several classes of D_p(G) theories. I, then, argue that we found the presence of 2-group symmetries in a class of Argyres-Douglas theories, called D_p(USp(2N)), which can be realized by Z_2-twisted compactification of the 6d N=(2,0) of the D-type on a sphere with an irregular twisted puncture and a regular twisted full puncture. I will also discuss the 3d mirror theories of general D_p(USp(2N)) theories that serve as an important tool to study their flavor symmetry and Higgs branch.
It is possible to join online via Zoom.
Twenty examples of AAA approximation
Abstract
For the first time, a method has become available for fast computation of near-best rational approximations on arbitrary sets in the real line or complex plane: the AAA algorithm (Nakatsukasa-Sète-T. 2018). After a brief presentation of the algorithm this talk will focus on twenty demonstrations of the kinds of things we can do, all across applied mathematics, with a black-box rational approximation tool.
Analysis and Numerical Approximation of Stationary Second-order Mean Field Game Partial Differential Inclusions
Abstract
The formulation of Mean Field Games (MFG) via partial differential equations typically requires continuous differentiability of the Hamiltonian in order to determine the advective term in the Kolmogorov--Fokker--Planck equation for the density of players. However, in many cases of practical interest, the underlying optimal control problem may exhibit bang-bang controls, which typically lead to nondifferentiable Hamiltonians. In this talk we will present results on the analysis and numerical approximation of stationary second-order MFG systems for the general case of convex, Lipschitz, but possibly nondifferentiable Hamiltonians. In particular, we will propose a generalization of the MFG system as a Partial Differential Inclusion (PDI) based on interpreting the derivative of the Hamiltonian in terms of subdifferentials of convex functions. We present results that guarantee the existence of unique weak solutions to the stationary MFG PDI under a monotonicity condition similar to one that has been considered previously by Lasry and Lions. Moreover, we will propose a monotone finite element discretization of the weak formulation of the MFG PDI, and present results that confirm the strong H^1-norm convergence of the approximations to the value function and strong L^q-norm convergence of the approximations to the density function. The performance of the numerical method will be illustrated in experiments featuring nonsmooth solutions. This talk is based on joint work with my supervisor Iain Smears.
Revisiting Two Classic Surface Tension Problems: Rough Capillary Rise and Fluctuations of Cellular Droplets
Abstract
In this talk I will discuss our recent work on two problems. The first problem concerns with capillary rise between rough structures, a fundamental wetting phenomenon that is functionalised in biological organisms and prevalent in geological or man-made materials. Predicting the liquid rise height is more complex than currently considered in the literature because it is necessary to couple two wetting phenomena: capillary rise and hemiwicking. Experiments, simulations and analytic theory demonstrate how this coupling challenges our conventional understanding and intuitions of wetting and roughness. For example, the critical contact angle for hemiwicking becomes separation-dependent so that hemiwicking can vanish for even highly wetting liquids. The rise heights for perfectly wetting liquids can also be different in smooth and rough systems. The second problem concerns with droplets (or condensates) formed via a liquid-liquid phase separation process in biological cells. Despite the widespread importance of surface tension for the interactions between these droplets and other cellular components, there is currently no reliable technique for their measurement in live cells. To address this, we develop a high-throughput flicker spectroscopy technique. Applying it to a class of cellular droplets known as stress granules, we find their interface fluctuations cannot be described by surface tension alone. It is necessary to consider elastic bending deformation and a non-spherical base shape, suggesting that stress granules are viscoelastic droplets with a structured interface, rather than simple Newtonian liquids. Moreover, given the broad distributions of surface tension and bending rigidity observed, different types of stress granules can only be differentiated via large-scale surveys, which was not possible previously and our technique now enables.
Prof Halim Kusumaatmaja is currently a Professor of Physics at Durham University and he also holds an EPSRC Fellowship in Engineering. Prof Kusumaatmaja graduated with a Master of Physics from the University of Leicester in 2004 and a PhD in Physics from the University of Oxford in 2008. He worked as a Postdoctoral Research Associate at the Max Planck Institute of Colloids and Interfaces (2008-2011) and at the University of Cambridge (2011-2013), before moving to Durham University and rising through the ranks from Assistant Professor (2013-2017) to Associate Professor (2017-2020) and Full Professor (2020-now). Prof Kusumaatmaja leads an interdisciplinary research group in the area of Soft Matter and Biophysics. Current research interests include wetting and interfacial phenomena, bio-inspired materials, liquid-liquid phase separation in biology, multistable elastic structures, colloidal and molecular self-assembly, and high performance computing.
OMI: Artificial Intelligence and Financial Markets workshop - 20th & 21st October 2022
Schedule, titles, abstracts, and bios can be found here.
16:00
$\ell^2$-invariants and generalisations in positive characteristic
Abstract
We survey the theory of $\ell^2$-invariants, their applications in group theory and topology, and introduce a positive characteristic version of $\ell^2$-theory. We also discuss the Atiyah and Lück approximation conjectures, two of the central problems in this area.
16:00
Equivariant Jiang-Su stability
Abstract
Equivariant Jiang-Su stability is an important regularity property for group actions on C*-algebras. In this talk, I will explain this property and how it arises naturally in the context of the classification of C*-algebras and their actions. Depending on the time, I will then explain a bit more about the nature of equivariant Jiang- Su stability and the kind of techniques that are used to study it, including a recent result of Gábor Szabó and myself establishing an equivalence with equivariant property Gamma under certain conditions.
Universal characteristics of deep neural network loss surfaces from random matrix theory
Abstract
Neural networks are the most practically successful class of models in modern machine learning, but there are considerable gaps in the current theoretical understanding of their properties and success. Several authors have applied models and tools from random matrix theory to shed light on a variety of aspects of neural network theory, however the genuine applicability and relevance of these results is in question. Most works rely on modelling assumptions to reduce large, complex matrices (such as the Hessians of neural networks) to something close to a well-understood canonical RMT ensemble to which all the sophisticated machinery of RMT can be applied to yield insights and results. There is experimental work, however, that appears to contradict these assumptions. In this talk, we will explore what can be derived about neural networks starting from RMT assumptions that are much more general than considered by prior work. Our main results start from justifiable assumptions on the local statistics of neural network Hessians and make predictions about their spectra than we can test experimentally on real-world neural networks. Overall, we will argue that familiar ideas from RMT universality are at work in the background, producing practical consequences for modern deep neural networks.
15:00
Random character varieties
Abstract
Consider a random group $\Gamma$ with $k$ generators and $r$ random relators of large length $N$. We study the geometry of the character variety of $\Gamma$ with values in $\SL(2,\C)$ or more generally any semisimple Lie group $G$. This is the moduli space of group homomorphisms from $\Gamma$ to $G$ up to conjugation. We are in particular able to determine its dimension, number of components and Galois group, with an excellent control on the probability of exceptions. The proofs use effective Chebotarev type theorems as well as new spectral gap bounds for Cayley graphs of finite simple groups. They are also conditional on GRH. Joint work with Peter Varju and Oren Becker.
Improved bounds for 1-independent percolation on $\mathbb{Z}^n$
Abstract
A 1-independent bond percolation model on a graph $G$ is a probability distribution on the spanning subgraphs of $G$ in which, for all vertex-disjoint sets of edges $S_1$ and $S_2$, the states (i.e. present or not present) of the edges in $S_1$ are independent of the states of the edges in $S_2$. Such models typically arise in renormalisation arguments applied to independent percolation models, or percolation models with finite range dependencies. A 1-independent model is said to percolate if the random subgraph has an infinite component with positive probability. In 2012 Balister and Bollobás defined $p_{\textrm{max}}(G)$ to be the supremum of those $p$ for which there exists a 1-independent bond percolation model on $G$ in which each edge is present in the random subgraph with probability at least $p$ but which does not percolate. A fundamental and challenging problem in this area is to determine, or give good bounds on, the value of $p_{\textrm{max}}(G)$ when $G$ is the lattice graph $\mathbb{Z}^2$. Since $p_{\textrm{max}}(\mathbb{Z}^n)\leq p_{\textrm{max}}(\mathbb{Z}^{n-1})$, it is also of interest to establish the value of $\lim_{n\to\infty}p_{\textrm{max}}(\mathbb{Z}^n)$.
In this talk we will present a significantly improved upper bound for this limit as well as improved upper and lower bounds for $p_{\textrm{max}}(\mathbb{Z}^2)$. We will also show that with high confidence we have $p_{\textrm{max}}(\mathbb{Z}^n)<p_{\textrm{max}}(\mathbb{Z}^2)$ for large $n$ and discuss some open problems concerning 1-independent models on other graphs.
This is joint work with Tom Johnston and Alex Scott.
14:00
The local Langlands correspondence and unitary representations of GL(n)
Abstract
Harish-Chandra's Lefschetz principle suggests that representations of real and p-adic split reductive groups are closely related, even though the methods used to study these groups are quite different. The local Langlands correspondence (as formulated by Vogan) indicates that these representation theoretic relationships stem from geometric relationships between real and p-adic Langlands parameters. In this talk we will discuss how the geometric structure of real and p-adic Langlands parameters lead to functorial relationships between representations of real and p-adic groups. I will describe work in progress which applies this functoriality to the study of unitary representations and signatures of invariant hermitian forms for GL(n). The main result expresses signatures of invariant hermitian forms on graded affine Hecke algebra modules in terms of signature characters of Harish-Chandra modules, which are computable via the unitary algorithm for real reductive groups by Adams-van Leeuwen-Trapa-Vogan.
12:30
Recovering scattering distributions from covariance-map images of product distributions
Abstract
Molecules can be broken apart with a high-powered laser or an electron beam. The position of charged fragments can then be detected on a screen. From the mass to charge ratio, the identity of the fragments can be determined. The covariance of two fragments then gives us the projection of a distribution related to the initial scattering distribution. We formulate the mathematical transformation from the scattering distribution to the covariance distribution obtained from experiments. We expand the scattering distribution in terms of basis functions to obtain a linear system for the coefficients, which we use to solve the inverse problem. Finally, we show the result of our method on three examples of test data, and also with experimental data.
16:30
A unified theory of lower Ricci curvature bounds for Riemannian and sub-Riemannian structures
Abstract
The synthetic theory of Ricci curvature lower bounds introduced more than 15 years ago by Lott-Sturm-Villani has been largely succesful in describing the geometry of metric measure spaces. However, this theory fails to include sub-Riemannian manifolds (an important class of metric spaces, the simplest example being the so-called Heisenberg group). Motivated by Villani's ``great unification'' program, in this talk we propose an extension of Lott-Sturm-Villani's theory, which includes sub-Riemannian geometry. This is a joint work with Barilari (Padua) and Mondino (Oxford). The talk is intended for a general audience, no previous knowledge of optimal transport or sub-Riemannian geometry is required.
16:00
On the Balog-Szemerédi-Gowers theorem
Abstract
The Balog-Szemerédi-Gowers theorem is a powerful tool in additive combinatorics, that allows one to roughly convert any “large energy” estimate into a “small sumset” estimate. This has found applications in a lot of results in additive combinatorics and other areas. In this talk, we will provide a friendly introduction and overview of this result, and then discuss some proof ideas. No hardcore additive combinatorics pre-requisites will be assumed.
15:30
4-manifolds with infinite cyclic fundamental group and knotted surfaces
Abstract
I will present classification results for 4-manifolds with boundary and infinite cyclic fundamental group, obtained in joint work with Anthony Conway and with Conway and Lisa Piccirillo. Time permitting, I will describe applications to knotted surfaces in simply connected 4-manifolds, and to investigating the difference between the relations of homotopy equivalence and stable homeomorphism. These will also draw on work with Patrick Orson and with Conway, Diarmuid Crowley, and Joerg Sixt.
Regularisation of differential equations by multiplicative fractional noises
Abstract
In this talk, we consider differential equations perturbed by multiplicative fractional Brownian noise. Depending on the value of the Hurst parameter $H$, the resulting equation is pathwise viewed as an ordinary ($H>1$), Young ($H \in (1/2, 1)$) or rough ($H \in (1/3, 1/2)$) differential equation. In all three regimes we show regularisation by noise phenomena by proving the strongest kind of well-posedness for equations with irregular drifts: strong existence and path-by-path uniqueness. In the Young and smooth regime $H>1/2$ the condition on the drift coefficient is optimal in the sense that it agrees with the one known for the additive case.
In the rough regime $H\in(1/3,1/2)$ we assume positive but arbitrarily small drift regularity for strong
well-posedness, while for distributional drift we obtain weak existence.
This is a joint work with Máté Gerencsér.
14:15
On the inverse problem for isometry groups of norms
Abstract
We study the problem of determining when a compact group can be realized as the group of isometries of a norm on a finite dimensional real vector space. This problem turns out to be difficult to solve in full generality, but we manage to understand the connected groups that arise as connected components of isometry groups. The classification we obtain is related to transitive actions on spheres (Borel, Montgomery-Samelson) on the one hand and to prehomogeneous spaces (Vinberg, Sato-Kimura) on the other. (joint work with Martin Liebeck, Assaf Naor and Aluna Rizzoli)
13:00
Semiclassics for Large Quantum Numbers
Abstract
According to the correspondence principle, classical physics emerges in the limit of large quantum numbers. We examine three examples of the semiclassical description of conformal field theory data: large charge boundary operators in the O(2) model, large spin impurities in the free triplet scalar field theory and large charge Wilson lines in QED. By simultaneously taking the coupling to zero and quantum numbers to infinity, we can connect the microscopic to the emergent classical description smoothly.
Meet and Greet Event
Abstract
Abstract:
Welcome (back) to Fridays@4! To start the new academic year in this session we’ll introduce what Fridays@4 is for our new students and colleagues. This session will be a chance to meet current students and ECRs from across Maths and Stats who will share their hints and tips on conducting successful research in Oxford. There will be lots of time for questions, discussions and generally meeting more people across the two departments – everyone is welcome!
Applied Topology for Discrete Structures
Abstract
Discrete structures have a long history of use in applied mathematics. Graphs and hypergraphs provide models of social networks, biological systems, academic collaborations, and much more. Network science, and more recently hypernetwork science, have been used to great effect in analyzing these types of discrete structures. Separately, the field of applied topology has gathered many successes through the development of persistent homology, mapper, sheaves, and other concepts. Recent work by our group has focused on the convergence of these two areas, developing and applying topological concepts to study discrete structures that model real data.
This talk will survey our body of work in this area showing our work in both the theoretical and applied spaces. Theory topics will include an introduction to hypernetwork science and its relation to traditional network science, topological interpretations of graphs and hypergraphs, and dynamics of topology and network structures. I will show examples of how we are applying each of these concepts to real data sets.
(From PNNL website)
Emilie's academic background is in pure mathematics, with a BS from University of Wisconsin - Madison and a PhD from Rutgers University, her research since joining PNNL in 2011 has focused on applications of combinatorics and computational topology together with theoretical advances needed to support the applications. Over her time at PNNL, Purvine has served as both a primary investigator and technical staff member on several projects in applications ranging from computational chemistry and biology to cybersecurity and power grid modeling. She has authored over 40 technical publications and is currently an associate editor for the Notices of the American Mathematical Society. Purvine also coordinates PNNL’s Postgraduate Organization which plans career development seminars, an annual research symposium, and promotes networking and mentorship for PNNL’s post bachelors, post masters, and post doctorate research associates.
14:00
Stochastic dynamics of cell fate decisions and the gene regulatory networks that underlie them
Abstract
Cell fate decision-making is responsible for development and homeostasis, and is dysregulated in disease. Despite great promise, we are yet to harness the high-resolution cell state information that is offered by single-cell genomics data to understand cell fate decision-making as it is controlled by gene regulatory networks. We describe how we leveraged joint dynamics + genomics measurements in single cells to develop a new framework for single-cell-informed Bayesian parameter inference of Ca2+ pathway dynamics in single cells. This work reveals a mapping from transcriptional state to dynamic cell fate. But no cell is an island: cell-internal gene regulatory dynamics act in concert with external signals to control cell fate. We developed a multiscale model to study the effects of cell-cell communication on gene regulatory network dynamics controlling cell fates in hematopoiesis. Specifically, we couple cell-internal ODE models with a cell signaling model defined by a Poisson process. We discovered a profound role for cell-cell communication in controlling the fates of single cells, and show how our results resolve a controversy in the literature regarding hematopoietic stem cell differentiation. Overall, we argue for the need to consider single-cell-resolved models to understand and predict the fates of cells.
16:00
The irrationality of a divisor function series of Erdös and Kac
Abstract
For positive integers $k$ and $n$ let $\sigma_k(n)$ denote the sum of the $k$th powers of the divisors of $n$. Erd\H{o}s and Kac conjectured that, for every $k$, the number $\alpha_k = \sum_{n\geq 1} \frac{\sigma_k(n)}{n!}$ is irrational. This is known conditionally for all $k$ assuming difficult conjectures like the Hardy-Littlewood prime $k$-tuples conjecture. Before our work it was known unconditionally that $\alpha_k$ is irrational if $k\leq 3$. We discuss some of the ideas in our recent proof that $\alpha_4$ is irrational. The proof involves sieve methods and exponential sum estimates.
MF-OMO: An Optimization Formulation of Mean-Field Games
Abstract
Theory of mean-field games (MFGs) has recently experienced an exponential growth. Existing analytical approaches to find Nash equilibrium (NE) solutions for MFGs are, however, by and large restricted to contractive or monotone settings, or rely on the uniqueness of the NE. We propose a new mathematical paradigm to analyze discrete-time MFGs without any of these restrictions. The key idea is to reformulate the problem of finding NE solutions in MFGs as solving an equivalent optimization problem, called MF-OMO (Mean-Field Occupation Measure Optimization), with bounded variables and trivial convex constraints. It is built on the classical work of reformulating a Markov decision process as a linear program, and by adding the consistency constraint for MFGs in terms of occupation measures, and by exploiting the complementarity structure of the linear program. This equivalence framework enables finding multiple (and possibly all) NE solutions of MFGs by standard algorithms such as projected gradient descent, and with convergence guarantees under appropriate conditions. In particular, analyzing MFGs with linear rewards and with mean-field independent dynamics is reduced to solving a finite number of linear programs, hence solvable in finite time. This optimization reformulation of MFGs can be extended to variants of MFGs such as personalized MFGs.
The definable (p,q) theorem for NIP theories
Abstract
I will discuss the following statement, a definable version of the (p,q) theorem of Jiří Matoušek from combinatorics, conjectured by Chernikov and Simon:
Suppose that T is NIP and that phi(x,b) does not fork over a model M. Then there is some formula psi(y) in tp(b/M) such that the partial type {phi(x,b’) : psi(b’)} is consistent.
14:00
1-form symmetry versus large N QCD
Note: we would recommend to join the meeting using the Zoom client for best user experience.
Abstract
It has long been appreciated that in QCD-like theories without fundamental matter, confinement can be given a sharp characterization in terms of symmetry. More recently, such symmetries have been identified as 1-form symmetries, which fit into the broader category of generalized global symmetries. In this talk I will discuss obstructions to the existence of a 1-form symmetry in large N QCD, where confinement is a sharp notion. I give general arguments for this disconnect between 1-form symmetries and confinement, and use 2d scalar QCD on the lattice as an explicit example.
It is possible to join online via Zoom.
Introduction to the Discrete De Rham complex
Abstract
Hilbert complexes are chains of spaces linked by operators, with properties that are crucial to establishing the well-posedness of certain systems of partial differential equations. Designing stable numerical schemes for such systems, without resorting to nonphysical stabilisation processes, requires reproducing the complex properties at the discrete level. Finite-element complexes have been extensively developed since the late 2000's, in particular by Arnold, Falk, Winther and collaborators. These are however limited to certain types of meshes (mostly, tetrahedral and hexahedral meshes), which limits options for, e.g., local mesh refinement.
In this talk we will introduce the Discrete De Rham complex, a discrete version of one of the most popular complexes of differential operators (involving the gradient, curl and divergence), that can be applied on meshes consisting of generic polytopes. We will use a simple magnetostatic model to motivate the need for (continuous and discrete) complexes, then give a presentation of the lowest-order version of the complex and sketch its links with the CW cochain complex on the mesh. We will then briefly explain how this lowest-order version is naturally extended to an arbitrary-order version, and briefly present the associated properties (Poincaré inequalities, primal and adjoint consistency, commutation properties, etc.) that enable the analysis of schemes based on this complex.
Mathematrix Meet and Greet
Abstract
Come along for free pizza and to hear about the Mathematrix events this term.
Thematic recommendations on knowledge graphs using multilayer networks
Abstract
We present a framework to generate and evaluate thematic recommendations based on multilayer network representations of knowledge graphs (KGs). We represent the relative importance of different types of connections (e.g., Directing/acting) with an intuitive salience matrix that can be learnt from data, tuned to incorporate domain knowledge, address different use cases, or respect business logic. We apply an adaptation of the personalised PageRank algorithm to multilayer network models of KGs to generate item-item recommendations. These recommendations reflect the knowledge we hold about the content, and are suitable for thematic or cold-start settings.
Evaluating thematic recommendations from user data presents unique challenges. Our method only recommends items that are 'thematically' related; that is, easily reachable following connections in the KG. We develop a variant of the widely-used Normalised Discounted Cumulative Gain (NDCG) to evaluate recommendations based on user-item ratings, respecting their thematic nature.
We apply our methods to a KG of the movie industry and MovieLens ratings and in an internal AB test. We learn the salience matrix and demonstrate that our approach outperforms existing thematic recommendation methods and is competitive with collaborative filtering approaches.
16:00
Profinite Rigidity
Abstract
Profinite rigidity is essentially the study of which groups can be distinguished from each other by their finite quotients. This talk is meant to give a gentle introduction to the area - I will explain which questions are the right ones to ask and give an overview of some of the main results in the field. I will assume knowledge of what a group presentation is.
16:00
Quantum limits
Abstract
In this talk, I will discuss the notion of quantum limits from different viewpoints: Cordes' work on the Gelfand theory for pseudo-differential operators dating from the 70’s as well as the micro-local defect measures and semi-classical measures of the 90’s. I will also explain my motivation and strategy to obtain similar notions in subRiemannian or subelliptic settings.
Analysis of solitonic interactions and random matrix theory
Abstract
I will describe the interaction between a single soliton and a gas of solitons, providing for the first time a mathematical justification for the kinetic theory as posited by Zakharov in the 1970s. Then I will explain how to use random matrix theory to introduce randomness into a large collection of solitons.
The Farrell-Jones Conjecture for the Hecke algebras of reductive p-adic groups
Abstract
We formulate and sketch the proof of the K-theoretic Farrell-Jones Conjecture for
for the Hecke algebras of reductive p-adic groups. This is the first time that
a version of the farrell-Jones Conjecture for topological groups is formulated. It implies that
the reductive projective class group of the Hecke algebra of a reductive p-adic group
is the colimit of these for all compact open subgroups. This has been proved rationally by
Bernstein and Dat using representation theory. The main applications of our result
will concern the theory of smooth representations
In particular we will prove a conjecture of Dat.
The proof is much more involved than the one for instance for discrete CAT(0)-groups.
We will only give a very brief sketch of it and the new problems occurring in the setting of
totally disconnected groups. Most of the talk will be devoted
an introduction to the Farrell-Jones Conjecture and the theory of
smooth representations of reductive p-adic groups, and
discussion of applications.
This is a joint project with Arthur Bartels.