Past

Please see http://www.cs.ox.ac.uk/seminars/CompBioPublicSeminars/

The optimal function spaces for the local-in-time well-posedness theory of the Navier-Stokes equations are closely related to the scaling symmetry of the equations. This might appear to be tied to particular methods used in the proofs, but in this talk we will raise the possibility that the equations are actually ill-posed for finite-energy initial data just at the borderline of some of the most benign scale-invariant spaces. This is related to debates about the adequacy of the Leray-Hopf weak solutions for predicting the time evolution of the system. (Joint work with Hao Jia.)

• Fabian Spill - Stochastic and continuum modelling of angiogenesis
• Matt Saxton - Modelling the contact-line dynamics of an evaporating drop
• Almut Eisentraeger - Water purification by (high gradient) magnetic separation

Note early start to avoid a clash with the OCCAM group meeting.

Sela showed that the theory of the non abelian free groups is stable. In a joint work with Sklinos, we give some characterization of the forking independence relation between elements of the free group F over a set of parameters A in terms of the Grushko and cyclic JSJ decomposition of F relative to A. The cyclic JSJ decomposition of F relative to A is a geometric group theory tool that encodes all the splittings of F as an amalgamated product (or HNN extension) over cyclic subgroups in which A lies in one of the factors.

So far, the circle method has been a very useful tool to prove
many cases of Manin's conjecture. Work of B. Birch back in 1961 establishes
this for smooth complete intersections in projective space as soon as the
number of variables is large enough depending on the degree and number of
equations. In this talk we are interested in subvarieties of biprojective
space. There is not much known so far, unless the underlying polynomials are
of bidegree (1,1). In this talk we present recent work which combines the
circle method with the generalised hyperbola method developed by V. Blomer
and J. Bruedern. This allows us to verify Manin's conjecture for certain
smooth hypersurfaces in biprojective space of general bidegree.

Lattice rules are equal-weight quadrature/cubature rules for the approximation of multivariate integrals which use lattice points as the cubature nodes. The quality of such cubature rules is directly related to the discrepancy between the uniform distribution and the discrete distribution of these points in the unit cube, and so, they are a kind of low-discrepancy sampling points. As low-discrepancy based cubature rules look like Monte Carlo rules, except that they use cleverly chosen deterministic points, they are sometimes called quasi-Monte Carlo rules.

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The talk starts by motivating the usage of Monte Carlo and then quasi-Monte Carlo methods after which some more recent developments are discussed. Topics include: worst-case errors in reproducing kernel Hilbert spaces, weighted spaces and the construction of lattice rules and sequences.

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In the minds of many, quasi-Monte Carlo methods seem to share the bad stanza of the Monte Carlo method: a brute force method of last resort with slow order of convergence, i.e., $O(N^{-1/2})$. This is not so.

While the standard rate of convergence for quasi-Monte Carlo is rather slow, being $O(N^{-1})$, the theory shows that these methods achieve the optimal rate of convergence in many interesting function spaces.

E.g., in function spaces with higher smoothness one can have $O(N^{-\alpha})$, $\alpha > 1$. This will be illustrated by numerical examples.

More than half of the world's financial markets use a limit order book

mechanism to facilitate trade. For markets where trade is conducted

through a central counterparty, trading platforms disseminate the same

information about the limit order book to all market participants in

real time, and all market participants are able to trade with all

others. By contrast, in markets that operate under bilateral trade

agreements, market participants are only able to view the limit order

book activity from their bilateral trading partners, and are unable to

trade with the market participants with whom they do not possess a

bilateral trade agreement. In this talk, I discuss the implications

of such a market structure for price formation. I then introduce a

simple model of such a market, which is able to reproduce several

important empirical properties of traded price series. By identifying and

matching several robust moment conditions to the empirical data, I make

model-based inference about the network of bilateral trade partnerships

in the market. I discuss the implications of these findings for market

stability and suggest how the regulator might improve market conditions

by implementing simple restrictions on how market participants form their

bilateral trade agreements.

Symplectic reflection algebras are an important class of algebras related to an incredibly high number of different topics such as combinatorics, noncommutative geometry and resolutions of singularities and have themselves a rich representation theory. We will recall their definition and classification coming from symplectic reflection groups and outline some of the results that have characterised their representation theory over the last decade, focusing on the link with representations of quivers.

We review the theory of $E_n$-algebras (roughly, algebras with $n$ compatible multiplications) and discuss $E_n$-deformation theory in the sense of Lurie. We then describe, to the best of our ability, the use of $E_n$-deformation theory in the on-going work of Calaque, Pantev, Toen, Vezzosi, and Vaquie about deformation quantization of derived stacks with shifted Poisson structure.

We review the theory of $E_n$-algebras (roughly, algebras with $n$ compatible multiplications) and discuss $E_n$-deformation theory in

the sense of Lurie. We then describe, to the best of our ability, the use of $E_n$-deformation theory in the on-going work of Calaque, Pantev, Toen,

Vezzosi, and Vaquie about deformation quantization of derived stacks with shifted Poisson structure.

***** PLEASE NOTE THAT THIS WILL TAKE PLACE ON TUESDAY 11TH JUNE ****

Signal transduction pathways are sophisticated information processing machinery in the cell that is arguably taking advantage of highly non-idealistic natures of intracellular environments for its optimum operations. In this study, we focused on effects of intracellular macromolecular crowding on signal transduction pathways using single-particle simulations. We have previously shown that rebinding of kinases to substrates can remarkably increase processivity of dual-phosphorylation reactions and change both steady-state and transient responses of the reaction network. We found that molecular crowding drastically enhances the rebinding effect, and it shows nonlinear time dependency although kinetics at the macroscopic level still follows the conventional model in dilute media. We applied the rate law revised on the basis of these calculations to MEK-ERK system and compared it with experimental measurements.

***** PLEASE NOTE THAT THIS WILL TAKE PLACE ON TUESDAY 11TH JUNE ****

The class of sofic groups was introduced by Gromov in 1999. It
includes all residually finite and all amenable groups. In fact, no group has been proved
not to be sofic, so it remains possible that all groups are sofic. Their
defining property is that, roughly speaking, for any finite subset F of
the group G, there is a map from G to a finite symmetric group, which is
approximates to an injective homomorphism on F. The widespread interest in
these group results partly from their connections with other branches of
mathematics, including dynamical systems. In the talk, we will concentrate
on their definition and algebraic properties.

In this talk, we consider the setting: a random realization of an evolving dynamical system, and explain how, using notions common in the theory of rough paths, such as the signature, and shuffle product, one can provide a new united approach to the fundamental problem of predicting the conditional distribution of the near future given the past. We will explain how the problem can be reduced to a linear regression and least squaresanalysis. The approach is clean and systematic and provides a clear gradation of finite dimensional approximations. The approach is also non-parametric and very general but still presents itself in computationally tractable and flexible restricted forms for concrete problems. Popular techniques in time series analysis such as GARCH can be seen to be restricted special cases of our approach but it is not clear they are always the best or most informative choices. Some numerical examples will be shown in order to compare our approach and standard time series models.

This talk is based on a joint work with Céline Labart. We are interested in this paper in the numerical simulation of solutions to Backward Stochastic Differential Equations. There are several existing methods to handle this problem and one of the main difficulty is always to compute conditional expectations.

Even though our approach can also be applied in the case of the dynamic programmation equation, our starting point is the use of Picard's iterations that we write in a forward way

In order to compute the conditional expectations, we use Wiener Chaos expansions of the underlying random variables. From a practical point of view, we keep only a finite number of terms in the expansions and we get explicit formulas.

We will present numerical experiments and results on the error analysis.

"We introduce some type of generalized Poisson formula which is equivalent 
to Langlands' automorphic transfer from an arbitrary reductive group over a 
global field to a general linear group."

The martingale optimal transportation problem is motivated by

model-independent bounds for the pricing and hedging exotic options in

financial mathematics.

In the simplest one-period model, the dual formulation of the robust

superhedging cost differs from the standard optimal transport problem by

the presence of a martingale constraint on the set of coupling measures.

The one-dimensional Brenier theorem has a natural extension. However, in

the present martingale version, the optimal coupling measure is

concentrated on a pair of graphs which can be obtained in explicit form.

These explicit extremal probability measures are also characterized as

the unique left and right monotone martingale transference plans, and

induce an optimal solution of the kantorovitch dual, which coincides

with our original robust hedging problem.

By iterating the above construction over n steps, we define a Markov

process whose distribution is optimal for the n-periods martingale

transport problem corresponding to a convenient class of cost functions.

Similarly, the optimal solution of the corresponding robust hedging

problem is deduced in explicit form. Finally, by sending the time step

to zero, this leads to a continuous-time version of the one-dimensional

Brenier theorem in the present martingale context, thus providing a new

remarkable example of Peacock, i.e. Processus Croissant pour l'Ordre

Convexe. Here again, the corresponding robust hedging strategy is

obtained in explicit form.