Our recent CDT alumna Milena Vuletic has been awarded  the 6th PLEXUS Award for AI in the Financial Sector for her DPhil thesis on Multi-asset financial markets: mathematical modelling and data-driven approaches.

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Fri, 16 Oct 2026

11:00 - 12:00
L4

Emergent phenomena in protein complexes out of equilibrium: from topologically-protected states to computation

Dr Jaime Agudo-Canalejo
(Dept of Physics & Astronomy UCL)
Abstract
Protein complexes, typically made up of a small number of identical subunits, are very common in biology. These subunits can additionally undergo post-translational modifications, such as phosphorylation and dephosphorylation, resulting in a high dimensional state space for the protein complex. Importantly, such modifications are catalyzed by enzymes that are driven out of equilibrium by the consumption of a fuel such as ATP. I will discuss, from a theoretical perspective, how very simple enzyme-catalyzed operations at the single subunit level can result in emergent behaviour at the level of the entire protein complex. First, I will discuss how topologically-protected edge currents emerge and become enhanced in arbitrarily high-dimensional stochastic systems representing the state of the complex, extending previous results for two-dimensional stochastic systems [1]. Second, I will discuss how enzymes that act on a subunit in a context-dependent manner provide a molecular implementation of stochastic cellular automata,  that can be exploited to engineer molecular-scale computing devices, such as an error-tolerant memory or a finite-state machine [2].
 
[1] E. Tang, J. Agudo-Canalejo, and R. Golestanian, Phys. Rev. X 11, 031015 (2021)
[2] J. Kocka, K. Husain, and J. Agudo-Canalejo, PRX Life 4, 013036 (2026)
Interest rate models in decentralised lending protocols
Cohen, S Sanchez Betancourt, L Szpruch, L Digital Finance
Fri, 19 Jun 2026
13:00
L4

Simplicial Novikov Homology

Vidit Nanda
Abstract

I will describe a circle-valued Morse theory for simplicial complexes. The central objects of study are partial matchings which admit certain zigzag cycles; these cyclic matchings lift canonically to acyclic matchings on the infinite cyclic cover of the underlying simplicial complex. From the lifted acyclic matchings, we obtain a finitely generated Morse chain complex defined over the Novikov ring, which consists of power series in one variable with finite negative support. We then establish a quasi-isomorphism between this Morse-Novikov complex and the simplicial chain complex of the cyclic cover, duly completed over the Novikov ring. As a pleasant consequence, we can define new computable invariants to detect (obstructions to) the fiberedness of tame knots.

Graded unitarity in the SCFT/VOA correspondence
Ardehali, A Beem, C Lemos, M Rastelli, L Journal of High Energy Physics volume 2026 issue 6 (05 Jun 2026)
Thu, 18 Jun 2026
11:00
C3

Model theory of limits II

Leo Gitin
(Oxford University)
Abstract

I will give an update on a proposed model theory for directed limits and colimits of first-order structures, originally motivated by applications to commutative algebra and the model theory of valued fields. To illustrate the usefulness of the formalism, I will prove a new general AKE theorem in mixed characteristic in a language with a cross-section of the value group and a lift of the residue field.

I will also discuss connections with other approaches to this topic, including pro- and ind-definable sets, infinitary logic, Feferman's local functors, accessible functors, and ultraproducts, some of which I have not discussed previously.

Matrix-Product State Skeletons in Onsager-Integrable Quantum Chains
Camp, I Jones, N Journal of Statistical Physics volume 193 issue 6 (15 Jun 2026)
Thu, 18 Jun 2026
17:00
L3

Unprovability Results in Complexity Theory

Rahul Santhanaam
(Oxford University)
Abstract
Several of the central conjectures in complexity theory, including the celebrated P vs NP question, remain wide open despite several decades of effort. It has been speculated that the difficulties in their resolution might have connections to incompleteness phenomena in logic. I will describe the framework of bounded arithmetic, which studies fragments of Peano Arithmetic where attention is limited to statements and reasoning of bounded complexity. I will briefly survey unprovability results in this area, and explain some challenges in extending these results to questions like P vs NP.

In 2022 Fantasy Premier League winner Josh Bull made his World Cup predictions. They were okay, but no cigar. However, in the intervening four years he has really honed his mathematical skills. Now he is 100% confident he's found the secret sauce.

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