Forthcoming events in this series


Thu, 19 Jun 2025

16:00 - 17:00
C1

Unusual transport in odd-diffusive systems

Erik Kalz
(University of Potsdam)
Further Information

Erik Kalz is a PhD student at U Potsdam in the group of Ralf Metzler. The group focuses on nonequilibrium statistical physics and anomalous stochastic processes, with applications to biological and soft matter systems.

Abstract

Odd systems, characterised by broken time-reversal or parity symmetry, 
exhibit striking transport phenomena due to transverse responses. In this 
talk, I will introduce the concept of odd diffusion, a generalisation of 
diffusion in two-dimensional systems that incorporates antisymmetric tensor 
components. Focusing on systems of interacting particles, I adapt a 
geometric approach to derive effective transport equations and show how 
interactions give rise to unusual transport in odd systems. I present 
effects like enhanced self-diffusion, reversed Hall drift and even absolute 
negative mobility that solely originate in odd diffusion. These results 
reveal how microscopic symmetry-breaking gives rise to emergent, equilibrium 
and non-equilibrium transport, with implications for soft matter, chiral 
active systems, and topological materials.

 

Wed, 18 Jun 2025

12:00 - 13:00
L3

Structures and Stability: Battling Beams, Kirigami Computing, and Eye Morphogenesis

Douglas Holmes
(Boston University College of Engineering)
Further Information

Short Bio
Douglas Holmes is a Professor in the Department of Mechanical Engineering at Boston University. He received degrees in Chemistry from the University of New Hampshire (B.S. 2004), Polymer Science & Engineering from the University of Massachusetts, Amherst (M.S. 2005, Ph.D. 2009), and was a postdoctoral researcher in Mechanical & Aerospace Engineering at Princeton University. Prior to joining Boston University, he was an Assistant Professor of Engineering Science & Mechanics at Virginia Tech. His research group specializes in the mechanics of slender structures, with a focus on understanding and controlling how objects change shape. His work has been recognized by the NSF CAREER Award, the ASEE Ferdinand P. Beer and E. Russell Johnston Jr. Outstanding New Mechanics Educator Award, and the Theo de Winter Distinguished Faculty Fellowship.

Abstract

Structural mechanics plays a crucial role in soft matter physics, mechanobiology, metamaterials, pattern formation, active matter, and soft robotics. What unites these seemingly disparate topics is the natural balance that emerges between elasticity, geometry, and stability. This seminar will serve as a high-level overview of our work on several problems concerning the stability of structures. I will cover three topics: (1) shapeshifting shells; (2) mechanical metamaterials; and (3) elastogranular mechanics.


I will begin by discussing our development of a generalized, stimuli-responsive shell theory. (1) Non-mechanical stimuli including heat, swelling, and growth further complicate the nonlinear mechanics of shells, as simultaneously solving multiple field equations to capture multiphysics phenomena requires significant computational expense. We present a general shell theory to account for non-mechanical stimuli, in which the effects of the stimuli are
generalized into three forms: those that add mass to the shell, those that increase the area of the shell through the natural stretch, and those that change the curvature of the shell through the natural curvature. I will show how this model can capture the morphogenesis of the optic cup, the snapping of the Venus flytrap, leaf growth, and the buckling of electrically active polymer plates. (2) I will then discuss how cutting thin sheets and shells, a process
inspired by the art of kirigami, enables the design of functional mechanical metamaterials. We create linear actuators, artificial muscles, soft robotic grippers, and mechanical logic units by systematically cutting and stretching thin sheets. (3) Finally, if time permits, I will introduce our work on the interactions between elastic and granular matter, which we refer to as elastogranular mechanics. Such interactions occur across all lengths, from morphogenesis, to root growth, to stabilizing soil against erosion. We show how combining rocks and string in the absence of any adhesive we can create large, load bearing structures like columns, beams, and arches. I will finish with a general phase diagram for elastogranular behavior.

 

 

Thu, 12 Jun 2025

12:00 - 13:00
L3

Microfluidic model of haemodynamics in complex media

Anne Juel
(University of Manchester)
Further Information

Short Bio
Anna Juel is a physicist whose research explores the complex dynamics of material systems, particularly in two-phase flows and wetting phenomena. Her group focuses on microfluidics, fluid-structure interactions, and complex fluid flows, with applications ranging from chocolate moulding to airway reopening and flexible displays. Based at the Manchester Centre for Nonlinear Dynamics, her experimental work often uncovers surprising behaviour, driving new insights through combined experimentation and modelling.

Abstract
The flow of red blood cells (RBCs) in heterogeneous biological porous tissues such as the human placenta, remains poorly understood despite the essential role the microvasculature plays in maintaining overall health and functionality of tissues, blood flow and transport mechanisms. This is in great part because the usual description of blood as a simple fluid breaks down when the size of RBCs is similar to that of the vessel. In this study, we use a bespoke suspension of ultra-soft microcapsules with a poroelastic membrane, which have been previously shown to mimic the motion and large deformations of RBCs in simple conduits [1], in order to explore soft suspension flows in planar porous media. Our planar porous devices are Hele-Shaw channels, where the capsules are slightly confined within the channel depth, and in which we increase confinement by adding regular or disordered arrays of pillars. We perform experiments that relate the global resistance of the suspension flow through the porous media to the local distributions of capsule concentration and velocity as a function of volume fraction, capillary number Ca, the ratio of viscous to elastic forces, and geometry. We find that the flow patterns in Hele-Shaw channels and ordered porous media differ significantly from those in disordered porous media, where the presence of capsules promotes preferential paths and supports anomalous capsule dispersion. In contrast, the flows in ordered geometries develop intriguing shear-banding patterns as the volume fraction increases. Despite the complex microscopic dynamics of the suspension flow, we observe the emergence of similar scaling laws for the global flow resistance in both regular and disordered porous media as a function of Ca. We find that the scaling exponent decreases with increasing volume fraction because of cooperative capsule mechanisms, which yield relative stiffening of the system for increasing Ca.
 
[1] Chen et al. Soft Matter 19, 5249- 5261.
 
Thu, 05 Jun 2025

12:00 - 13:00
L3

Constitutive Modeling of the Microstructure of Arterial Walls Including Collagen Cross-Linking

Gerhard Holzapfel
(TU Graz)
Further Information

Extended Bio
Gerhard A. Holzapfel is a world-leading figure in biomechanics, currently serving as Professor and Head of the Institute of Biomechanics at Graz University of Technology (TUG), Austria. He also holds appointments as Adjunct Professor at the Norwegian University of Science and Technology (NTNU) in Trondheim and Visiting Professor at the University of Glasgow. From 2004 to 2013, he was Professor of Biomechanics at the Royal Institute of Technology (KTH) in Stockholm.

Following a PhD in Mechanical Engineering from Graz, Professor Holzapfel was awarded an Erwin Schrödinger Scholarship, enabling him to conduct research at Stanford University. He achieved his Habilitation at TU Vienna in 1996 and was the recipient of Austria’s prestigious START Award in 1997. Over subsequent decades, he has led pioneering work in computational biomechanics, including as Head of the Computational Biomechanics research group at TUG (1998–2004).

Professor Holzapfel has received numerous accolades, including the Erwin Schrödinger Prize of the Austrian Academy of Sciences (2011), listings among “The World’s Most Influential Scientific Minds” (Thomson Reuters, 2014), the William Prager Medal and Warner T. Koiter Medal (2021), an honorary doctorate from École des Mines de Saint-Étienne (2024), and election to the U.S. National Academy of Engineering (2025). In 2024, he was awarded a prestigious Synergy Grant from the European Research Council (ERC).

His research spans experimental and computational biomechanics and mechanobiology, with a particular focus on soft biological tissues and the cardiovascular system in both health and disease. His expertise includes nonlinear continuum mechanics, constitutive modelling, growth and remodeling, imaging and image-based modeling, and the mechanics of therapeutic interventions such as angioplasty and stenting.

Professor Holzapfel is the author of the widely adopted graduate textbook Nonlinear Solid Mechanics (Wiley), has co-edited seven additional books, and contributed chapters to over 30 volumes. He has published more than 300 peer-reviewed journal articles. He is also the co-founder and co-editor of the journal Biomechanics and Modeling in Mechanobiology (Springer). His work has been funded by numerous national and international agencies, including the Austrian Science Fund, NIH, the European Commission, and industry collaborators.

Abstract

Nowadays, the 3D ultrastructure of a fibrous tissue can be reconstructed in order to visualize the complex nanoscale arrangement of collagen fibrils including neighboring proteoglycans even in the stretched loaded state [1]. In particular, experimental data of collagen fibers in human artery layers have shown that the f ibers are not symmetrically dispersed [2]. In addition, it is known that collagen f ibers are cross-linked and the density of cross-links in arterial tissues has a stiffening effect on the associated mechanical response. A first attempt to characterize this effect on the elastic response is presented and the influence of the cross-link density on the mechanical behavior in uniaxial tension is shown [3]. A recently developed extension of the model that accounts for dispersed fibers connected by randomly distributed cross-links is outlined [4]. A simple shear test focusing on the sign of the normal stress perpendicular to the shear planes (Poynting effect) is analyzed. In [5] it was experimentally observed that, in contrast to rubber, semi-flexible biopolymer gels show a tendency to approach the top and bottom faces under simple shear. This so-called negative Poynting effect and its connection with the cross-links as well as the fiber and crosslink dispersion is also examined. 

References 

[1]A. Pukaluk et al.: An ultrastructural 3D reconstruction method for observing the arrangement of collagen fibrils and proteoglycans in the human aortic wall under mechanical load. Acta Biomaterialia, 141:300-314, 2022. 

 [2] G.A. Holzapfel et al.: Modelling non-symmetric collagen fibre dispersion in arterial walls. Journal of the Royal Society Interface, 12:20150188, 2015. 

 [3] G.A. Holzapfel and R.W. Ogden: An arterial constitutive model accounting for collagen content and cross-linking. Journal of the Mechanics and Physics of Solids, 136:103682, 2020. 

 [4] S. Teichtmeister and G.A. Holzapfel: A constitutive model for fibrous tissues with cross-linked collagen fibers including dispersion – with an analysis of the Poynting effect. Journal of the Mechanics and Physics of Solids, 164:104911, 2022. 

[5] P.A. Janmey et al.: Negative normal stress in semiflexible biopolymer gels. Nature Materials, 6:48–51, 2007.

 

Thu, 29 May 2025

12:00 - 13:00
L3

Pressure-driven fracture in elastic continuum materials

Peter Stewart
(University of Glasgow)
Further Information

Short Bio
Peter S. Stewart is a Professor of Applied Mathematics at the University of Glasgow. His research applies continuum mechanics to physiological and industrial problems. He previously held postdoctoral positions at the University of Oxford and Northwestern University, and earned his PhD from the University of Nottingham with a thesis on flows in flexible channels and airways. http://www.maths.gla.ac.uk/~pstewart

Abstract
Experiments indicate that a monolayer of gas-liquid foam confined within a Hele-Shaw cell can exhibit brittle fracture when subject to an applied driving pressure. In this talk we characterise this brittle fracture mode by considering the propagation of an internally pressurised crack though a slab of elastic continuum material with low resistance to shear, extending the classical description of pressure-driven fracture in a linearly elastic material to a slab of finite-width. We employ a novel matched eigenfunction expansion approach to formulate the stress field, incorporating a global penalty term which we isolate by solving a Fredholm integral equation. We recover the well-known stress singularity in the neighbourhood of the crack tip, but demonstrate that the spatial extent of this stress field in the direction of the crack is set by the domain width irrespective of the shear modulus of the material. The versatility of this approach allows for considerable modifications in the physical properties of the fracturing material, including those characteristic of foams, where out-of-plane deflection of the structural elements and accompanying viscous resistance to motion over the plates of the Hele-Shaw cell are important. These modifications facilitate a solution of the continuum model in the limit of zero shear modulus, where the stress singularity is entirely absent and the lengthscale of the stress-field in the direction of the crack is instead set by the dissipation coefficients. We exploit this mis-match in lengthscales to construct an asymptotic description for a slender domain, analytically characterising the critical conditions for crack propagation as a function of the driving pressure and the domain width. Furthermore, we show that this outer asymptotic solution can be extended to describe materials with low but finite shear modulus, where the accompanying stress singularity around the crack tip is confined within a boundary layer adjacent to the crack surface.
 
 
 
 
Thu, 22 May 2025

12:00 - 13:00
L3

Accelerating Predictions of Turbulent Combustion and Nonequilibrium Flows Using Solver-Embedded Deep Learning

Jonathan MacArt
(Univ. of Notre Dame)
Further Information

Short Bio
Jonathan MacArt leads the Reacting Turbulence Lab, where he and his team develop high-performance computational tools to study how flow physics interact with phenomena like chemical heat release and plasma kinetics. Their work includes large-scale DNS, LES, RANS simulations, and physics-informed machine learning, with applications ranging from gas turbines to hypersonic propulsion systems.

Abstract

Predictions of complex flows remain a significant challenge for engineering systems. Computationally affordable predictions of turbulent flows generally require Reynolds-Averaged Navier–Stokes (RANS) simulations and Large-Eddy Simulation (LES), the predictive accuracy of which can be insufficient due to non-Boussinesq turbulence and/or unresolved multiphysics that preclude qualitative fidelity in certain regimes. For example, in turbulent combustion, flame–turbulence interactions can lead to inverse-cascade energy transfer, which violates the assumptions of many RANS and LES closures. We present an adjoint-based, solver-embedded data assimilation method to augment the RANS and LES equations using trusted data. This is accomplished using Python-native flow solvers that leverage differentiable programming techniques to construct the adjoint equations needed for optimization. We present applications to shock-tube ignition delay predictions, turbulent premixed jet flames, and shock-dominated nonequilibrium flows and discuss the potential of adjoint-based approaches for future machine learning applications.

 

Thu, 08 May 2025

12:00 - 13:00
L3

Low-rank methods for discovering structure in data tensors in neuroscience

Alex Cayco-Gajic
(École Normale Supérieure Paris)
Further Information

Short Bio

Alex Cayco Gajic is a Junior Professor in the Department of Cognitive Studies at ENS, with a background in applied mathematics and a PhD from the University of Washington. Her research bridges computational modelling and data analysis to study cerebellar function, exploring its roles beyond motor control in collaboration with experimental neuroscientists.

Abstract

A fundamental question in neuroscience is to understand how information is represented in the activity of  tens of thousands of neurons in the brain. Towards this end, low-rank matrix and tensor decompositions are commonly used to identify correlates of behavior in high-dimensional neural data. In this talk I will first present a novel tensor decomposition based on the slice rank which is able to disentangle mixed modes of covarying patterns in data tensors. Second, to compliment this statistical approach, I will present our recent dynamical systems modelling of neural activity over learning. Rather than factorizing data tensors themselves, we instead fit a dynamical system to the data, while constraining the tensor of parameters to be low rank. Together these projects highlight how applications in neural data can inspire new classes of low-rank models.

Thu, 01 May 2025

12:00 - 13:00
L3

Do Plants Know Math?: Adventures of a Mathematician in Science Writing

Christophe Golé
(Smith College)
Further Information

Short Bio
Christophe Golé is a mathematician originally from France, with academic positions held at institutions including ETH Zurich and UC Santa Cruz. He is the author of Symplectic Twist Maps, a book on dynamical systems, and coined the term “ghost tori” in this context. His recent work focuses on mathematical biology, particularly plant pattern formation (phyllotaxis) and the occurrence of Fibonacci numbers in nature. He co-founded the NSF-funded 4 College Biomath Consortium, which led to the Five College Biomathematical Sciences Certificate Program.

Abstract

"Do Plants Know Math?" is the title of a book I co-authored with physicist Stéphane Douady, biologist Jacques Dumais, and writer Nancy Pick. Written for a general audience with a historical perspective, the book primarily explores phyllotaxis—the arrangement of leaves and other organs around plant stems—while also examining plant fractals, kirigami models of leaf formation, and related phenomena.

To our knowledge, phyllotaxis represents the first historical intersection of biological and mathematical research. Delving into its history uncovers remarkable treasures: phyllotaxis studies led to the first formulation of renormalization (van Iterson, 1907) and inspired one of the earliest computer programs (developed by Turing in the last years of his life).

In this talk, I will highlight several of these hidden historical gems while discussing the productive symbiosis between our scientific research on phyllotaxis and the creation of our book.

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Thu, 13 Mar 2025

12:00 - 13:00
L3

Some methods for finding vortex equilibria

Robb McDonald
(UCL)
Further Information

Robb McDonald is a Professor in the Department of Mathematics. His research falls into two areas: 

(i) geophysical fluid dynamics, including rotating stratified flows, rotating hydraulics, coastal outflows, geophysical vortices and topographic effects on geophysical flows.
(ii) complex variable methods applied to 2D free-boundary problems. This includes vortex dynamics, Loewner evolution, Hele-Shaw flows and Laplacian growth, industrial coating problems, and pattern formation in nature.

 

Abstract

Determining stationary compact configurations of vorticity described by the 2D Euler equations is a classic problem dating back to the late 19th century. The aim is to find equilibrium distributions of vorticity, in the form  of point vortices, vortex sheets, vortex patches, and hollow vortices. This endeavour has driven the development of mathematical and numerical techniques such as Hamiltonian vortex dynamics and contour dynamics.

In the case of vortex sheets, methods and results are presented for finding rotating equilibria, some in the presence of point vortices. To begin, a numerical approach based on that recently developed by Trefethen, Costa, Baddoo, and others for solving Laplace's equation in the complex plane by series and rational approximation is described. The method successfully reproduces the exact vortex sheet solutions found by O'Neil (2018) and Protas & Sakajo (2020). Some new solutions are found.

The numerical approach suggests an analytical method based on conformal mapping for finding exact closed-form vortex sheet equilibria. Examples are presented.

Finally, new numerical solutions are computed for steady, doubly-connected vortex layers of uniform vorticity surrounding a solid object such that the fluid velocity vanishes on the outer free boundary. While dynamically unrelated, these solutions have mathematical analogy and application to the industrial free boundary problem arising in the dip-coating of objects by a viscous fluid.

 

Thu, 27 Feb 2025

12:00 - 13:00
L2

Coarse-grained models for schooling swimmers in fast flows

Anand Oza
(New Jersey Institute of Technology)
Further Information

Anand Oza is Associate Professor in the Department of Mathematical Sciences as a part of the Complex Flows and Soft Matter (CFSM) Group. He is interested in fluid mechanics and nonlinear dynamics, with applications to soft matter physics and biology. His research utilizes a combination of analytical techniques and numerical simulations, collaborating with experimentalists whenever possible.

Abstract

The beautiful displays exhibited by fish schools and bird flocks have long fascinated scientists, but the role of their complex behavior remains largely unknown. In particular, the influence of hydrodynamic interactions on schooling and flocking has been the subject of debate in the scientific literature. I will present a model for flapping wings that interact hydrodynamically in an inviscid fluid, wherein each wing is represented as a plate that executes a prescribed time-periodic kinematics. The model generalizes and extends thin-airfoil theory by assuming that the flapping amplitude is small, and permits consideration of multiple wings through the use of conformal maps and multiply-connected function theory. We find that the model predictions agree well with experimental data on freely-translating, flapping wings in a water tank. The results are then used to motivate a reduced-order model for the temporally nonlocal interactions between schooling wings, which consists of a system of nonlinear delay-differential equations. We obtain a PDE as the mean-field limit of these equations, which we find supports traveling wave solutions. Generally, our results indicate how hydrodynamics may mediate schooling and flocking behavior in biological contexts.

 

Thu, 20 Feb 2025

12:00 - 13:00
L3

Advanced Effective Models in Elasticity

Claire Lestringant
(Sorbonne University)
Further Information

Dr Claire Lestringant explores new models for understanding the mechanics of thin structures under large deformations, used for example to understand morphogenesis in biological systems or for the design of multi-stable, reconfigurable space structures. She received a PhD in Mechanics from Université Pierre et Marie Curie in 2017 and worked as a post-doc in D. Kochmann’s group at ETH Zurich in Switzerland.

Abstract

I will discuss two classes of effective, macroscopic models in elasticity: (i) 1D models applicable to thin structures, and (ii) homogenized 2D or 3D continua applicable to materials with a periodic microstructure. In both systems, the separation of scales calls for the definition of macroscopic models that slave fine-scale fluctuations to an effective, macroscopic deformation field. I will show how such models can be established in a systematic and rigorous way based on a two-scale expansion that accounts for nonlinear and higher-order (i.e. deformation gradient) effects. I will further demonstrate that the resulting models accurately predict nonlinear effects, finite size effects and localization for a set of examples. Finally, I will discuss two challenges that arise when solving these effective models: (1) missed boundary layer effects and (2) negative stiffness associated with higher-order terms.

Thu, 13 Feb 2025

12:00 - 13:00
L3

Various

Various Speakers from OCIAM Year 2 Graduates
(Mathematical Institute)
Thu, 13 Feb 2025
12:00
L3

OCIAM TBC

OCIAM TBC
Thu, 06 Feb 2025

12:00 - 13:00
L3

Modelling flying formations and vortex ring motions

Christiana Mavroyiakoumou
( Courant Institute of Mathematical Sciences)
Further Information

Christiana is an Assistant Professor at the Courant Institute of Mathematical Sciences (New York University) working in the Applied Math Lab, primarily with Leif Ristroph and Jun Zhang. Her interests are in using modeling, numerical simulations, and experiments to study fluid dynamical problems, with an emphasis on fluid-structure interactions.

Currently Christiana is working on understanding the role of flow interactions in flying bird formations and the hydrodynamics of swimming fish.

Abstract

We consider two problems in fluid dynamics: the collective locomotion of flying animals and the interaction of vortex rings with fluid interfaces. First, we present a model of formation flight, viewing the group as a material whose properties arise from the flow-mediated interactions among its members. This aerodynamic model explains how flapping flyers produce vortex wakes and how they are influenced by the wakes of others. Long in-line arrays show that the group behaves as a soft, excitable "crystal" with regularly ordered member "atoms" whose positioning is susceptible to deformations and dynamical instabilities. Second, we delve into the phenomenon of vortex ring reflections at water-air interfaces. Experimental observations reveal reflections analogous to total internal reflection of a light beam. We present a vortex-pair--vortex-sheet model to simulate this phenomenon, offering insights into the fundamental interactions of vortex rings with free surfaces.

Thu, 30 Jan 2025

12:00 - 13:00
L3

Spontaneous shape transformations of active surfaces

Alexander Mietke
(Department of Physics)
Further Information

Alexander Mietke is a theoretical physicist working on active and living matter. He frequently collaborates with experimentalists who study processes at the cell, tissue and organism scale to identify minimal physical principles that guide these processes. This often inspires new theoretical work on topics in non-equilibrium soft matter physics, more broadly in the self-organization of mechanical and chemical patterns in active matter, the emergent shape dynamics of membranes and active surfaces, liquid crystals in complex geometries, chirality in active systems, as well as in developing coarse-graining and inference approaches that are directly applicable to experimental data. 

Abstract

Biological matter has the fascinating ability to autonomously generate material deformations via intrinsic active forces, where the latter are often present within effectively two-dimensional structures. The dynamics of such “active surfaces” inevitably entails a complex, self-organized interplay between geometry of a surface and its mechanical interactions with the surrounding. The impact of these factors on the self-organization capacity of surfaces made of an active material, and how related effects are exploited in biological systems, is largely unknown.

In this talk, I will first discuss general numerical challenges in analysing self-organising active surfaces and the bifurcation structure of emergent shape spaces. I will then focus on active surfaces with broken up-down symmetry, of which the eukaryotic cell cortex and epithelial tissues are highly abundant biological examples. In such surfaces, a natural interplay arises between active stresses and surface curvature. We demonstrate that this interplay leads to a comprehensive library of spontaneous shape transformations that resemble stereotypical morphogenetic processes. These include cell-division-like invaginations and the autonomous formation of tubular surfaces of arbitrary length, both of which robustly overcome well-known shape instabilities that would arise in analogue passive systems.

 

 

Thu, 23 Jan 2025

12:00 - 13:00
L3

Optimal design of odd active solids

Anton Souslov
(University of Cambridge)
Further Information

Anton Souslov is an Associate Professor of Theoretical Statistical Physics working on the theory of soft materials, including mechanical metamaterials, active matter, topological states, and polymer physics.

Abstract

Active solids consume energy to allow for actuation and shape change not possible in equilibrium. I will first introduce active solids in comparison with their active fluid counterparts. I will then focus on active solids composed of non-reciprocal springs and show how so-called odd elastic moduli arise in these materials. Odd active solids have counter-intuitive elastic properties and require new design principles for optimal response. For example, in floppy lattices, zero modes couple to microscopic non-reciprocity, which destroys odd moduli entirely in a phenomenon reminiscent of rigidity percolation. Instead, an optimal odd lattice will be sufficiently soft to activate elastic deformations, but not too soft. These results provide a theoretical underpinning for recent experiments and point to the design of novel soft machines.

 

 

Thu, 05 Dec 2024

12:00 - 13:00
L3

Chaotic flows in polymer solutions: what’s new?

Prof. Rich Kerswell
(University of Cambridge)
Further Information

Rich Kerswell is a professor in the Department of Applied Mathematics and Theoretical Physics (DAMTP) at the University of Cambridge. His research focuses on fluid dynamics, particularly in the transition to turbulence, geophysical fluid flows, and nonlinear dynamics. Kerswell is known for studying how simple fluid systems can exhibit complex, chaotic behavior and has contributed to understanding turbulence's onset and sustainment in various contexts, including pipes and planetary atmospheres. His work integrates mathematical modeling, theoretical analysis, and computational simulations to explore instabilities and the fundamental mechanisms governing fluid behavior in nature and industry.

Abstract

It is well known that adding even small amounts of  long chain polymers (e.g. few parts per million) to Newtonian solvents can drastically change the flow behaviour by introducing elasticity. In particular,  two decades ago, experiments in curved geometries  demonstrated  that polymer flows can be  chaotic even at vanishingly small Reynolds numbers. The situation in `straight’ flows  such as pressure-driven flow down a channel is less clear  and hence an area of current focus. I will discuss recent progress.

Thu, 21 Nov 2024

12:00 - 13:00
L3

Tension-induced giant actuation in elastic sheets (Marc Sune) Deciphering Alzheimer's Disease: A Modelling Framework for In Silico Drug Trials (Georgia Brennan)

Dr Marc Suñé & Dr Georgia Brennan
(Mathematical Institute)
Abstract

Tension-induced giant actuation in elastic sheets

Dr. Marc Suñé

Buckling is normally associated with a compressive load applied to a slender structure; from railway tracks in extreme heat to microtubules in cytoplasm, axial compression is relieved by out-of-plane buckling. However, recent studies have demonstrated that tension applied to structured thin sheets leads to transverse motion that may be harnessed for novel applications, such as kirigami grippers, multi-stable `groovy-sheets', and elastic ribbed sheets that close into tubes. Qualitatively similar behaviour has also been observed in simulations of thermalized graphene sheets, where clamping along one edge leads to tilting in the transverse direction. I will discuss how this counter-intuitive behaviour is, in fact, generic for thin sheets that have a relatively low stretching modulus compared to the bending modulus, which allows `giant actuation' with moderate strain.

Thu, 07 Nov 2024

12:00 - 13:00
L3

Translational Applications of Mathematical and Computational Modeling in Respiratory and Critical Care Medicine

Prof. Samir Ghadiali
((Imperial College)
Further Information

Samir Ghadiali is Professor and Chair/Head of the Department of Biomedical Engineering at the Ohio State University (OSU) and a Professor of Pulmonary and Critical Care Medicine at the OSU Wexner Medical Center. Dr. Ghadiali is a Fellow of the American Institute of Medical and Biological Engineering, the Biomedical Engineering Society and is a Parker B. Francis Fellow in Pulmonary Research. He is a member of the Davis Heart & Lung Research Institute and the Biophysics Graduate Program at OSU, and his internationally recognized research program uses biomedical engineering tools to develop novel diagnostic platforms and drug/gene therapies for cardiovascular and respiratory disorders. His research has been funded by the National Science Foundation, National Institutes of Health, the American Heart Association, and the United States Department of Defense and he has mentored over 35 pre-doctoral and post-doctoral trainees who have gone on to successful academic, industrial and research careers. 

Abstract

The global COVID19 pandemic has highlighted the lethality and morbidity associated with infectious respiratory diseases. These diseases can lead to devastating syndrome known as the acute respiratory distress syndrome (ARDS) where bacterial/viral infections cause excessive lung inflammation, pulmonary edema, and severe hypoxemia (shortness of breath). Although ARDS patients require artificial mechanical ventilation, the complex biofluid and biomechanical forces generated by the ventilator exacerbates lung injury leading to high mortality. My group has used mathematical and computational modeling to both characterize the complex mechanics of lung injury during ventilation and to identify novel ways to prevent injury at the cellular level. We have used in-vitro and in-vivo studies to validate our mathematical predictions and have used engineering tools to understand the biological consequences of the mechanical forces generated during ventilation. In this talk I will specifically describe how our mathematical/computational approach has led to novel cytoskeletal based therapies and how coupling mathematics and molecular biology has led to the discovery of a gene regulatory mechanisms that can minimize ventilation induced lung injury. I will also describe how we are currently using nanotechnology and gene/drug delivery systems to enhance the lung’s native regulatory responses and thereby prevent lung injury during ARDS.

Thu, 31 Oct 2024

12:00 - 13:00
L3

Volcanic fissure localisation and lava delta formation: Modelling of volcanic flows undergoing rheological evolution

Jesse Taylor-West
(University of Bristol)
Abstract
In this talk, I will present two volcanologically motivated modelling problems.  In the first, I will detail how thermoviscous localisation of volcanic eruptions is influenced by the irregular geometry of natural volcanic fissures. Fissure eruptions typically start with the opening of a linear fissure that erupts along its entire length, following which activity localises to one or more isolated vents within a few hours or days. Previous work has proposed that localisation can arise through a thermoviscous fingering instability driven by the strongly temperature dependent viscosity of the rising magma. I will show that, even for relatively modest variations of the fissure width, a non-planar geometry supports strongly localised steady states, in which the wider parts of the fissure host faster, hotter flow, and the narrower parts of the fissure host slower, cooler flow. This geometrically-driven localisation is different from, and typically more potent than, the thermoviscous fingering localisation observed in planar geometries.  
 
The second problem concerns lava delta formation. A lava delta arises when a volcanic lava flow enters a body of water, extending the pre-eruption shoreline via the creation of new, flat land. A combination of cooling induced rheological changes and the reduction in gravitational driving forces controls the morphology and evolution of the delta. I will present shallow-layer continuum models for this process, highlighting how different modes of delta formation manifest in different late-time behaviours.
Thu, 24 Oct 2024

12:00 - 13:00
L3

Effective elasticity and dynamics of helical filaments under distributed loads

Michael Gomez
(Kings College London)
Abstract

Slender elastic filaments with intrinsic helical geometry are encountered in a wide range of physical and biological settings, ranging from coil springs in engineering to bacteria flagellar filaments. The equilibrium configurations of helical filaments under a variety of loading types have been well studied in the framework of the Kirchhoff rod equations. These equations are geometrically nonlinear and so can account for large, global displacements of the rod. This geometric nonlinearity also makes a mathematical analysis of the rod equations extremely difficult, so that much is still unknown about the dynamic behaviour of helical rods under external loading.

An important class of simplified models consists of 'equivalent-column' theories. These model the helical filament as a naturally-straight beam (aligned with the helix axis) for which the extensional and torsional deformations are coupled. Such theories have long been used in engineering to describe the free vibrations of helical coil springs, though their validity remains unclear, particularly when distributed forces and moments are present. In this talk, we show how such an effective theory can be derived systematically from the Kirchhoff rod equations using the method of multiple scales. Importantly, our analysis is asymptotically exact in the small-wavelength limit and can account for large, unsteady displacements. We then illustrate our theory with two loading scenarios: (i) a heavy helical rod deforming under its own weight; and (ii) axial rotation (twirling) in viscous fluid, which may be considered as a simple model for a bacteria flagellar filament. More broadly, our analysis provides a framework to develop reduced models of helical rods in a wide variety of physical and biological settings, as well as yielding analytical insight into their tensile instabilities.