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The currently available quantum computers fall into the NISQ (Noisy Intermediate Scale Quantum) regime. These enable variational algorithms with a relatively small number of free parameters. We are now entering the FTQC (Fault Tolerant Quantum Computer)  regime where gate fidelities are high enough that error-correction schemes are effective. The UK Quantum Missions include the target for a FTQC device that can perform a million operations by 2028, and a trillion operations by 2035.

This talk will present the outcomes from assessments of  two quantum linear equation solvers for FTQCs– the Harrow–Hassidim–Lloyd (HHL) and the Quantum Singular Value Transform (QSVT) algorithms. These have used sample matrices from a Computational Fluid Dynamics (CFD) testcase. The quantum solvers have also been embedded with an outer non-linear solver to judge their impact on convergence. The analysis uses circuit emulation and is used to judge the FTQC requirements to deliver quantum utility.

Our visual perception of the world heavily relies on sophisticated and delicate biological mechanisms, and any disruption to these mechanisms negatively impacts our lives. Age-related macular degeneration (AMD) affects the central field of vision and has become increasingly common in our society, thereby generating a surge of academic and clinical interest. I will present some recent developments in the mathematical modeling of the retinal pigment epithelium (RPE) in the retina in the context of AMD; the RPE cell layer supports photoreceptor survival by providing nutrients and participating in the visual cycle and “cellular maintenance". Our objectives include modeling the aging and degeneration of the RPE with a mechanistic approach, as well as predicting the progression of atrophic lesions in the epithelial tissue. This is a joint work with the research team of Prof. M. Paques at Hôpital National des Quinze-Vingts.

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We are going to study the Ginzburg-Landau energy for two specific geometries, related to the very experiments on fermionic condensates: annuli and strips 

The specific geometry of a strip provides connections between solitons and vortices, called solitonic vortices, which are vortices with a solitonic behaviour in the infinite direction of the strip. Therefore, they are very different from classical vortices which have an algebraic decay at infinity. We show that there exist stationary solutions to the Gross-Pitaevskii equation with k vortices on a transverse line, which bifurcate from the soliton solution as the width of the strip is increased. This is motivated by recent experiments on the instability of solitons by imposing a phase shift in an elongated condensate for bosonic or fermionic atoms.

For annuli, we prescribe a very large degree on the outer boundary and find that either there is a transition from a giant vortex to vortices also in the bulk but tending to the outer boundary.

This is joint work with Ph. Gravejat and E.Sandier for solitonice vortices and Remy Rodiac for annuli.
 

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We investigate pattern formation for a 2D PDE-ODE bulk-cell model, where one or more bulk diffusing species are coupled to nonlinear intracellular
reactions that are confined within a disjoint collection of small compartments. The bulk species are coupled to the spatially segregated
intracellular reactions through Robin conditions across the cell boundaries. For this compartmental-reaction diffusion system, we show that
symmetry-breaking bifurcations leading to stable asymmetric steady-state patterns, as regulated by a membrane binding rate ratio, occur even when
two bulk species have equal bulk diffusivities. This result is in distinct contrast to the usual, and often biologically unrealistic, large
differential diffusivity ratio requirement for Turing pattern formation from a spatially uniform state. Secondly, for the case of one-bulk
diffusing species in R^2, we derive a new memory-dependent ODE integro-differential system that characterizes how intracellular
oscillations in the collection of cells are coupled through the PDE bulk-diffusion field. By using a fast numerical approach relying on the
``sum-of-exponentials'' method to derive a time-marching scheme for this nonlocal system, diffusion induced synchrony is examined for various
spatial arrangements of cells using the Kuramoto order parameter. This theoretical modeling framework, relevant when spatially localized nonlinear
oscillators are coupled through a PDE diffusion field, is distinct from the traditional Kuramoto paradigm for studying oscillator synchronization on
networks or graphs. (Joint work with Merlin Pelz, UBC and UMinnesota).

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The hydrodynamic description for emergent behavior of interacting agents is governed by Euler alignment equations, driven by different protocols of pairwise communication kernels. A main question of interest is how short- vs. long-range interactions dictate the large-crowd, long-time dynamics. 

The equations lack closure for the pressure away thermal equilibrium. We identify a distinctive feature of Euler alignment -- a reversed direction of entropy. We discuss the role of a reversed entropy inequality in selecting mono-kinetic closure for emergence of strong solutions, prove the existence of such solutions, and characterize their related invariants which extend the 1-D notion of an “e” quantity.